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New ULS Equipment - ThermoFisher Krios G4 300 kV Cryo-TEM System

26 Sep 2023

Equipment update

The University Research Facility in Life Sciences (ULS) is excited to announce that our ThermoFisher Krios G4 300 kV Cryogenic Transmission Electron Microscope (Cryo-TEM) is now open to users. The Krios G4 is a highly stable 300 kV cryo-TEM platform with the Selectris energy filter that allows researchers to examine biological specimens at near-atomic resolution. As the final and most crucial step in the cryo-EM workflow, the Krios G4 enables data collection for subsequent structural analysis of challenging biological targets, such as large complexes, flexible species and membrane proteins, as well as cryo-electron tomography (cryo-ET) analysis for determination of 3D biological structures in their near-native states. The exceptionally high performance of the system will substantially improve and accelerate data collection, and as a result the development of potential therapeutics.


If you have any enquiries about the Krios G4 300 kV Cryo-TEM or the cryo-EM technique, please do not hesitate to contact Mr Sirui Li or Dr Harvey Chan of the ULS.


Thank you for your attention. May we wish you a delightful mid-autumn festival.

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