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Light sheet fluorescence microscopy (LSFM), also termed selective plane illumination microscopy (SPIM), is a planar illumination technique in which fluorescence excitation and detection are decoupled into separate optical pathways. With this novel optical design, illumination using a thin laser light sheet provides an inherent optical sectioning capability without the need to adopt a pinhole, which significantly improves the efficiency of photon collection and imaging speed without compromising image quality. LSFM allows researchers to examine live, intact animal models, ex vivo tissue explants, 3-dimensional cell cultures and organoids, etc., at unprecedented speed with virtually no photobleaching or photocytotoxicity.

Discount for long-duration bookings:

  • Applicable to consecutive bookings of 8 hours or longer
  • A 50% discount will be applied to any segments that fall within non-office hours (i.e., from 6 pm to 9 am on weekdays, and the whole days on Saturdays, Sundays and public holidays)
  • Price adjustments, if any, will be made after the completion of the imaging session
  • The ULS reserves the right to interpret these terms


Dr. Michael Yuen

Senior Scientific Officer

Dr. Eva Lau

Scientific Officer

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