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ULS Equipment Upgrade - Abberior STED Super-resolution Microcsope

18 Sep 2023

Equipment update

The University Research Facility in Life Sciences (ULS) is pleased to announce that our Abberior STED Super-resolution Microscope has completed an upgrade in Germany and is now re-open to users. The new MATRIX detector on our STED system is an array-type avalanche photodiode detector (APD) consisting of more than 20 single-photon-counting APDs in a hexagonal arrangement. The array of APDs can simultaneously image the sample from different angles, and identify and subtract background signals in STED images using physical principles instead of image postprocessing, substantially improving the sign-to-noise ratio.


In addition, the new detector will enable researchers to perform fluorescence lifetime imaging microscopy (FLIM) in combination with STED (i.e., STED-FLIM) or confocal microscopy. These would make the STED system the most powerful and versatile fluorescence microscope the ULS has to offer.


If you have any enquiries about the STED system, please do not hesitate to contact Dr Michael Yuen.


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