Publications

The interplay of UBE2T and Mule in regulating Wntβ-catenin activation to promote hepatocellular carcinoma progression. Cell Death and Disease (2021) 12:148.

Ho NPY, Leung CON, Wong TL, Lau EYT, Lei MML, Mok EHK, Leung HW, Tong M, Ng, IOL, Yun JP, Ma S, Lee TKW (2021)

Cryo-Electron Microscopy

Fluorescence Microscopy

Small Animal Research Platform

Genomics and Molecular Biology

ABCT

Selective Estrogen Receptor Modulator-Like Activities of Herba epimedii Extract and its Interactions With Tamoxifen and Raloxifene in Bone Cells and Tissues. Frontiers in Pharmacology 2021, 11, 571598. doi: 10.3389/fphar.2020.571598

Zhou, L.; Wong, K. Y.; Yu, X.; Poon, C. C. W.; Xiao, H. H.; Chan, C. O.; Mok, D. K. W.; Zhang, Y.; Wong, M. S., (2021)

Mass Spectrometry

ABCT

Synthesis of 1,3,4-trisubstituted pyrrolidines as meropenem adjuvants targeting New Delhi metallo-β-lactamase. New Journal of Chemistry 2021, 45, 7, 3515-3534.

Jin, W.B.; Xu, C.; Qi, X. L.; Zheng, P.; Gao, W.; Lai, K. H.; Chiou, J.; Chan, E. W. C.; Leung, Y. C.; Chan, T. H.; Wong, K. Y.; Chen, S., (2021)

Mass Spectrometry

ABCT

Quantitative Analysis of Blended Oils by Matrix-assisted Laser Desorption/Ionization Mass Spectrometry and Partial Least Squares Regression. Food Chem. 2021, 334, 127601.

Li, S. Y.; Ng, T. T.; Yao, Z. P., (2021)

Mass Spectrometry

ABCT

Multifunctional Nanotheranostic Gold Nanocage/Selenium Core-Shell for PAI-Guided Chemo-Photothermal Synergistic Therapy in vivo. Int J Nanomedicine. 2020; 15: 10271–10284.

Fang X, Lui KH, Li S, Lo WS, Li X, Gu Y, Wong WT (2020)

Small Animal Research Platform

ABCT

Icariin ameliorates estrogen-deficiency induced bone loss by enhancing IGF-I signaling via its crosstalk with non-genomic ERα signaling. Phytomedicine 2021,82:153413. doi: 10.1016/j.phymed.2020.153413

Zhou, L.; Poon, C. C. W.; Wong, K. Y.; Cao, S.; Dong, X.; Zhang, Y.; Wong, M. S., (2021)

Fluorescence Microscopy

ABCT

Hydrogen-Deuterium Exchange Mass Spectrometry for Probing Changes in Conformation and Dynamics of Proteins. Methods Mol Biol . 2021;2199:159-173.

So PK

Mass Spectrometry

Fluid Shear Stress Induces EMT of Circulating Tumor Cells via JNK Signaling in Favor of Their Survival during Hematogenous Dissemination. Int. J. Mol. Sci. 2020, 21(21), 8115.

Xin Y, Li K, Yang M, Tan Y (2020)

Cryo-Electron Microscopy

Fluorescence Microscopy

BME

The adaptor protein APPL2 controls glucose-stimulated insulin secretion via F-actin remodeling in pancreatic β-cells. PNAS. 2020 Nov; 117 (45) 28307-28315

Wang B, Lin H, Li X, Lu W, Kim JB, Xu A, Cheng KKY (2020)

Fluorescence Microscopy

HTI

Quantitative characterization of the colorectal cancer in a rabbit model using high-frequency endoscopic ultrasound. Ultrasonics 110 (2021) 106289.

Liu C, Yang Y, Qiu W, Chen Y, Dai J, Sun L (2021)

Small Animal Research Platform

BME