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A mitochondria-targeting and G-quadruplex structure-binding ligand inducing calcium overload and ferroptosis in human cancer cells. Brit J Pharmacol 2025, 182 (16), 3923-3951. DOI: 10.1111/bph.70061.

Zheng, B. X.; Long, W.; Zeng, Y. X.; She, M. T.; Zheng, Y. Y.; Zheng, W. D.; Wang, Y. K.; Chan, K. H.; Leung, A. S. L.; Chan, C. M.; et al.

Biochemical Analysis

Cellular and Molecular Biology

Fluorescence Microscopy

General Research

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Epac1 Mediates Thermogenesis and Lipolysis in White Adipose Tissue via the P38γ-NFAT5 Axis in a PKA-Independent Manner. Clinical Science 2025, 139 (12), 649–665. https://doi.org/10.1042/CS20256710.

Wang, B.; Chen, C. Y.; Liu, J.; Wang, Q.; Zhang, W.; Liu, J.; Tai, A. C. P.; Kai, A.; Ko, B. C. B.; Xu, A.; Chung, S. K

Cellular and Molecular Biology

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Polypharmacology-Driven Discovery of ZAK-I-57: A Potent Multi-Targeted Benzoxazinone Small Molecule for Hepatocellular Carcinoma Therapy. Medcomm 2025, 6 (8).

Khan, S. A.; Yang, H. H.; Ying, F.; Chu, C. N.; Lee, T. K. W.

Mass Spectrometry

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Tetrandrine regulates NAADP-mediated calcium signaling through a LIMP-2-dependent and sphingosine-mediated mechanism. Nat Commun 2025, 16 (1). DOI: ARTN 630810.1038/s41467-025-61565-9.

Chan, W. C.; Zhao, Q.; Wong, K. H.; Tang, H. H.; Mok, D. K. W.; Pardeshi, L.; Ruan, Y. C.; Yang, Y.; Wong, C. M.; Wong, C. T. T.; et al.

Cellular and Molecular Biology

Fluorescence Microscopy

Mass Spectrometry

Preclinical Animal Research

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BME

FSN

HTI

Facilitating PET Imaging: Eco-Friendly Purification Using Solid-Phase Material for Labeling Metal-Based Radiopharmaceuticals. Jacs Au 2025, 5 (7), 3213- 3218.

Yeung, Y. H.; Zhang, L.; Kai, H. Y.; Lam, P. L.; Zhang, T.; Wu, Y.; Law, G. L.; Xie, C.; Wong, K. L.

Mass Spectrometry

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Supramolecular Interactions Determined Macroscopic Robotic Actuation Processes of Azobenzene Amphiphiles. Small 2025, e2503359. DOI: 10.1002/smll.202503359

Liu, B. B.; Zhang, H.; Wong, W. K.; Chau, M. H.; Cheung, L. H.; Kajitani, T.; Leung, F. K.

Biochemical Analysis

Mass Spectrometry

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Bioorthogonal Reaction of o-Quinone with Furan-2(3H)-One for Site Selective Tyrosine Conjugation and Construction of Bispecific Antibody Complexes. Adv Sci 2025, 12 (22). DOI: 10.1002/advs.202417260.

Chen, H. F.; Xu, Z. Y.; Bao, Y. S.; Shiri, F.; Yuan, D. D.; Hu, Y. K.; Li, B. Q.; Zeng, B.; Li, X. J.; Kong, H.; et al.

Cryo-Electron Microscopy

Fluorescence Microscopy

Mass Spectrometry

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External

Directionally Modulated Zinc Deposition by a Robust Zincophilic Cu-Phthalocyanine Protective Layer in Dendrite-Free Aqueous Zinc Ion Batteries. Adv. Mater. 37, no. 33 (2025): 37, 2503086.

Wang, Y. D.; Jiang, X. W.; Liang, W. H.; Tawiah, B.; Wang, Y.; Jia, H.; Wong, W. Y.

Mass Spectrometry

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Excited-State Engineering toward Accelerated Reverse Intersystem Crossing in Diindolocarbazole-Embedded Multiple-Resonance Emitters for High-Performance Blue OLEDs. Acs Appl Mater Inter 2025, 17 (21), 31192-31200.

Wang, S. X.; Zhou, J. P.; Jin, J. B.; Jiang, H.; Mai, M. Q.; Duan, L.; Zhang, X. P.; Wong, W. Y.

Mass Spectrometry

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Etching-Based Chiroplasmonic Sensing with Helicoid Au Nanocrystals for Anti-Interference Biochemical Detection. Small 2025, 21 (26), 2500888. https://doi.org/10.1002/smll.202500888.

Luan, X.; Wu, F.; Lv, X.; Li, F.; Tian, Y.; Xu, G.; Wang, X.; Zheng, G.; Wong, W.; Wong, K.; Niu, W.

Biochemical Analysis

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