Skip to main content Start main content

Departmental Academic Advisors

a166_2050x500
Prof. Lin Xihong

Prof. Lin Xihong

Departmental Academic Advisor

Biography

Professor Lin Xihong is Professor and former Chair of the Department of Biostatistics, Coordinating Director of the Program in Quantitative Genomics at the Harvard T. H. Chan School of Public Health, and Professor of the Department of Statistics at the Faculty of Arts and Sciences of Harvard University, and Associate Member of the Broad Institute of Harvard and MIT.

Professor Lin is an elected member of the National Academy of Medicine. She received the 2002 Mortimer Spiegelman Award from the American Public Health Association, and the 2006 Committee of Presidents of Statistical Societies (COPSS) Presidents’ Award and the 2017 COPSS FN David Award. She is an elected fellow of American Statistical Association (ASA), Institute of Mathematical Statistics, and International Statistical Institute.

Prof. Lin’s research interests lie in development and application of statistical and computational methods for analysis of massive data from genome, exposome and phenome, and scalable statistical inference and learning for big genomic, epidemiological and health data.  Examples include analytic methods and applications for large scale Whole Genome Sequencing studies, biobanks and electronic health records, whole genome variant functional annotations, genes and environment, multiple phenotype analysis, risk prediction, integrative analysis of different types of data, causal mediation analysis and causal inference, analysis of epidemiological and complex observational study data. Her theoretical and computational statistical research includes statistical methods for testing a large number of complex hypotheses, causal inference, statistical inference for large covariance matrices, prediction models using high-dimensional data, cloud-based statistical computing, and statistical methods for epidemiological studies.

Prof. Lin’s statistical methodological research has been supported by the MERIT Award (R37) (2007-2015) and the Outstanding Investigator Award (OIA) (R35) (2015-2022) from the National Cancer Institute (NCI). She is the contact PI of the Harvard Analysis Center of the Genome Sequencing Program of the National Human Genome Research Institute, and the multiple PI of the U19 grant on Integrative Analysis of Lung Cancer Etiology and Risk from NCI. She is also the contact PI of the T32 training grant on interdisciplinary training in statistical genetics and computational biology.  She is the former contact PI of the Program Project (PO1) on Statistical Informatics in Cancer Research from NCI.

Prof. Lin is the former Chair of the COPSS (2010-2012) and a former member of the Committee of Applied and Theoretical Statistics (CATS) of the National Academy of Science. She co-launched the new Section of Statistical Genetics and Genomics of the American Statistical Association and served as a former section chair. She is the former Coordinating Editor of Biometrics and the founding co-editor of Statistics in Biosciences.  She has served on a large number of committees of many statistical societies, and numerous NIH and NSF review panels.

Research Interests

  • High dimensional data
  • Statistical genetics and genomics
  • Pathway and network association analysis
  • Correlated data (clustered/longitudinal and spatial data)
  • Case-control and cohort data
  • Nonparametric and semiparametric regression
  • Estimating equations and mixed models
  • Measurement error
  • Causal inference

Your browser is not the latest version. If you continue to browse our website, Some pages may not function properly.

You are recommended to upgrade to a newer version or switch to a different browser. A list of the web browsers that we support can be found here