- Y821
- +852 3400 8680
- ga-lai.law@polyu.edu.hk
ORCID ID
SCOPUS IDResearch Overview
The distinctive electronic properties of f-elements, particularly lanthanides, has enabled the design and development of advanced luminescent materials and molecular probes for cutting-edge imaging and sensing applications. Recent advancements on molecular f-element chemistry in our group has focus on the development of chiral supramolecular assemblies with unique topologies as well as chiral macrocyclic lanthanide complexes for circularly polarized luminescence (CPL) and multimodal imaging for diagnostics and theranostics.
Research Interests
Education and Academic Qualifications
- Master of Chemistry, The University of Manchester
- Doctor of Philosophy, The University of Hong Kong
Academic and Professional Experience
- Member, The Royal Society of Chemistry
- Member, American Chemical Society
Achievements
- Zhang, J.; Dai, L.; He, L.; Bhattarai, A.; Chan, C.-M.; Tai, W. C.-S.; Vardhanabhuti, V.; Law, G.-L. Design and synthesis of chiral DOTA-based MRI contrast agents with remarkable relaxivities. Communications Chemistry 2023, 6, 251. DOI: 10.1038/s42004-023-01050-w
- Zhang, J.; Dai, L.; Webster, A. M.; Chan, W. T. K.; Mackenzie, L. E.; Pal, R.; Cobb, S. L.; Law, G.-L. Unusual Magnetic Field Responsive Circularly Polarized Luminescence Probes with Highly Emissive Chiral Europium(III) Complexes. Angewandte Chemie International Edition 2021, 60, 1004–1010. DOI: https://doi.org/10.1002/anie.202012133
- Dai, L.; Zhang, J.; Wong, C. T.; Chan, W. T. K.; Ling, X.; Anderson, C. J.; Law, G.-L. Design of Functional Chiral Cyclen-Based Radiometal Chelators for Theranostics. Inorganic Chemistry 2021, 60, 7082–7088. DOI: 10.1021/acs.inorgchem.0c03734
- Wong, H.-Y.; Lo, W.-S.; Yim, K.-H.; Law, G.-L. Chirality and Chiroptics of Lanthanide Molecular and Supramolecular Assemblies. Chem 2019, 5, 3058–3095. DOI: https://doi.org/10.1016/j.chempr.2019.08.006
- Dai, L.; Jones, C. M.; Chan, W. T. K.; Pham, T. A.; Ling, X.; Gale, E. M.; Rotile, N. J.; Tai, W. C.-S.; Anderson, C. J.; Caravan, P.; Law, G.-L. Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications. Nature Communications 2018, 9, 857. DOI: 10.1038/s41467-018-03315-8
- Yeung, C.-T.; Yim, K.-H.; Wong, H.-Y.; Pal, R.; Lo, W.-S.; Yan, S.-C.; Yee-Man Wong, M.; Yufit, D.; Smiles, D. E.; McCormick, L. J.; Teat, S. J.; Shuh, D. K.; Wong, W.-T.; Law, G.-L. Chiral transcription in self-assembled tetrahedral Eu4L6 chiral cages displaying sizable circularly polarized luminescence. Nature Communications 2017, 8, 1128. DOI: 10.1038/s41467-017-01025-1
