Prof. Tse is an Associate Professor at the School of Optometry, The Hong Kong Polytechnic University (PolyU), with expertise in myopia control and retinal physiology. After earning my BSc in Optometry (2005) and PhD in Vision Science (2009) from PolyU, I pursued postdoctoral training in Australia (2009–2011) on a PolyU-University of Newcastle myopia project, followed by research at Baylor College of Medicine (2011–2014) under Prof. Samuel Wu on retinal circuitry and neuroscience. Returning to PolyU in 2014 as a Research Assistant Professor, I advanced to Assistant Professor (2016) and Associate Professor (2020). In the School of Optometry of PolyU, Dr Tse serves as the Director of the Clinical Trial Unit for Vision, and the Director of Research Postgraduate Studies.

Myopia. Prof. Tse’s research interest is to understand the physiological mechanisms that control eye growth, including optical signals, retinal circuitry, and biochemical signaling pathways. I commenced my investigations by characterizing the optical defocus signals that modulate eye growth, using animal models of chick, guinea pig, and monkey. I played a significant role in designing optical systems, writing patent applications, and supervising clinical trials to translate this Myopic Defocus Technology for human application. It has led to the commercialization of contact lenses and spectacle lenses that inhibit myopia progression in children, and these lenses are now available in more than 30 countries. Selected publications are listed below. His research has been supported by the Research Impact Fund and General Research Fund from the Research Grants Council of HK, the Innovation and Technology Support Programme, and the Health@InnoHK cluster from the Innovation and Technology Commission of HK.

Prof. Tse’s research focuses on understanding the mechanism of myopia and developing treatments for myopia by elucidating physiological mechanisms of eye growth—optical signals, retinal pathways, and biochemical cascades. Using animal models, I characterized optical defocus signals that regulate eye growth, laying the groundwork for the Myopic Defocus Technology. With over 50 peer-reviewed articles and a track record of commercialization, I currently lead clinical and basic research projects at PolyU to refine myopia interventions, leveraging my global training and collaborations.