Academic Staff
- Y817-03
- +852 3400 8668
- xiaoli.dong@polyu.edu.hk
Research Overview
My research interests include pathogenic mechanism studies of neurodegenerative diseases (Parkinson’s disease in particular); novel therapy (especially food-based therapies) development for treatment of neurodegenerative diseases and medicinal/functional food development for mental health.
Education and Academic Qualifications
- Bachelor of Medicine, Jining Medical College
- Master of Medicine, Qingdao University Medical College
- Doctor of Philosophy, The Hong Kong Polytechnic University
Research Interests
Achievements
- 黄家兴,董晓莉,都中蕊,刘鑫。功能化纳米硒水溶胶及其治疗神经退行性疾病的应用。中国专利,申请号:202211032665.1
- 黄家兴,董晓莉,陆家谦。一种功能化纳米硒水溶胶于抗肿瘤方面的应用。中国专利,申请号:202210637693.X
- 黄家兴,董晓莉,陆家谦,张兆滔。一种纳米硒水溶胶及其制备方法与应用。中国专利,已授权,专利号:ZL 2019 1 1215358.5
- 黄文秀,董晓莉,于文轩。维生素D补充制剂及其应用。中国专利,已授权,专利号:ZL 2019 1 0764988.1
- 黄文秀,董晓莉,曹思思,王奕。齐敦果酸和熊果酸在制备调节维生素D3代谢酶活性的药物中的应用。中国专利,已授权 专利号:ZL 2017 1 1061004.0
- 黄文秀,姚新生,邱佐成,董晓莉,戴毅。异戊烯基二氢黄酮类化合物在防治骨疾病领域的应用 中国专利,已授权 专利号:ZL 2016 1 0102211.5
- 李小花,董晓莉,赵清,张焕。三萜类化合物在制备治疗帕金森药物中的应用。中国专利,已授权 专利号:ZL 2015 1 0673284.5
- Li YH, Jiang ZX, Xu Q, Jin TT, Huang JF, Luan X, Li C, Chen XY, Wong KH*, Dong XL*, Sun XR*. Inhibition of calcium-sensing receptor by its antagonist promotes gastrointestinal motility in a Parkinson’s disease mouse model. Biomedicine & Pharmacotherapy, 2024, 174, 116518 (IF: 7.5; JCR Q1)
- Cao X, Du ZR, Liu X, Wang X, Li C, Zhou SN, Liu JR, Xu PY, Ye JL, Zhao Q, Zhao F, Wong KH*, Dong XL*. Low and high doses of oral maslinic acid protect against Parkinson’s disease via distinct gut microbiota-related mechanisms. Biomedicine & Pharmacotherapy, 2023, 165, 115100. (IF: 7.5; JCR Q1)
- Sun CC, Du ZR, Liu X, Yang Y, Zhou SN, Li C, Cao X, Zhao Q, Wong KH, Chen WF*, Dong XL*. Selenium forms and dosages determined their biological actions in mouse models of Parkinson’s Disease. Nutrients, 2023, 15: 11 (IF: 5.9; JCR Q1)
- Liu X, Du ZR, Wang X, Sun XR, Zhao Q, Zhao F, Wong WT, Wong KH*, Dong XL*. Polymannuronic acid prebiotic plus Lacticaseibacillus rhamnosus GG probiotic as a novel synbiotic promoted their separate neuroprotection against Parkinson’s disease. Food Research International, 2022, 155: 111067 (IF: 8.1; JCR Q1)
- Du ZR, Wang X, Cao X, Liu X, Zhou SN, Zhang H, Yang RL, Wong KH, Tang QJ*, Dong XL*. Alginate and its two components acted differently against dopaminergic neuronal loss in Parkinson's Disease mice model. Molecular Nutrition & Food Research, 2022, 66(2): e2100739 (IF: 5.2; JCR Q1)
- Liu X, Du ZR, Wang X, Luk KH, Chan CH, Cao X, Zhao Q, Zhao F, Wong WT, Wong KH*, Dong XL*. Colonic dopaminergic neurons changed reversely with those in the midbrain via gut microbiota-mediated autophagy in a chronic Parkinson’s disease mice model. Frontiers in Aging Neuroscience, 2021, 13: 649627 (IF: 4.8; JCR Q2)
- Dong XL, Wang X, Liu F, Liu X, Du ZR, Li RW, Xue CH, Wong KH, Wong WT, Zhao Q, Tang QJ. Polymannuronic acid prevents dopaminergic neuronal loss via brain-gut-microbiota axis in Parkinson’s disease model. International Journal of Biological Macromolecules, 2020, 164: 994-1005 (IF: 8.2; JCR Q1)