Academic Staff
- TU515a
- +852 3400 2675
- fang9.zhang@polyu.edu.hk
- Personal Website
ORCID ID
SCOPUS IDResearch Overview
Fang Zhang’s research bridges biosensor innovation, food safety, and public health, with a strong emphasis on Cas/Ago-based diagnostics, nanomaterials, and functional nucleic acids aiming for rapid, simple, field-deployable detection.
Academic and Professional Experience
Research Fellow, City University of Hong Kong (2023–2025)
Postdoc, University of Waterloo (2019–2020)
Postdoc, University of Waterloo (2019–2020)
Research Interests
Research Output
- Zhang F*, Liew SW, Lam SY, Kwok CK*. Nucleic acid-guided protein-empowered aquatic contaminants sensing. Trends in Chemistry. 2025,7(12) 853-868.
- Zhong, H., X. Huang, G. Chen, T. Zhang, D. Mao, Z. Lin and F. Zhang (2025). "Self-assembled DNAzyme based on the nicking enzyme amplification reaction for microRNA detection." Anal Methods 17(35): 7026-7032.
- Zhang, Z., C. Wu, L. Bai, K. Guo, T. Wang, D. Liu, M. Zhu, F. Qian, F. Zhang and R. Wang (2025). "MVPCR: Multiplex Visual Detection Strategy Based on Ultrafast PCR for Point-of-Care Pathogens Detection Within 10 Min." Phenomics 5(3): 239-251.
- Chencheng Wei, Handong Wang, Gaozheng Li, Jianhua Li, Fang Zhang, Yuezhong Wu*, Zuquan Weng*. Multiplex detection methods for mycotoxins in agricultural products: a systematic review. Food Control 2024, 158, 110207.
- Lanmei Gao, Houbing Zheng, Yuanlong Hu, Yi Zhon, Linhai Jian, Yuanzi Wu, Fen Ya, Da Huang, Jianhua Li, Fang Zhang*, Zhenyu Lin, Meishui Wang*, Zuquan Weng*. Fluorescent biosensor based on MB-APT combined with Pt NPs for the detection of infectious bacteria in mouse and human wounds. Sensors and Actuators B: Chemical, 2023, 393: 134318.
- Ganghui Chen1,2, Dongsheng Mao1, Xuan Wang1, Jingqi Chen1, Chao Gu1, Shuqin Huang2, Yu Yang1*, Fang Zhang2* and Weihong Tan. Aptamer-based self-assembled nanomicelle enables efficient and targeted drug delivery. Journal of Nanobiotechnology 2023, 21,415.
- Liu Wang a d e 1, Linlin Bai a b c 1, Hongmei Wang a, Kaiyu He a, Rui Wang b, Qiang Wang*a, Fang Zhang*c, Xiahong Xu*a, Graphene oxide assisting the visual detection of Salmonella by CRISPR/Cas12a. Microchemical Journal 2023,191,108870.
- Huan Zeng, Shuqin Huang, Yunong Chen, Minshi Chen, Kaiyu He, Caili Fu, Qiang Wang, Fang Zhang*, Liu Wang*, Xiahong Xu. Label-Free Sequence-Specific Visualization of LAMP Amplified Salmonella via DNA Machine Produces G-Quadruplex DNAzyme. Biosensors 13(5), 2023, 503.
- Fang Zhang*, Ganghui Chen, Chenshan Gao, Shuqin Huang, Yishan Mahu, Fang Luo, Lixin Wang*, Zhenyu Lin*. Updated toolkits for nucleic acid-based biosensors. Trends in Analytical Chemistry,159,2023,116943.
- Liu Wang, Fang He, Xueyun Chen, Kaiyu He, Linlin Bai, Qiang Wang, Fang Zhang*, Xiahong Xu*. A CRISPR/Cas12a-based label-free fluorescent method for visual signal output. Sensors and Actuators B: Chemical, 370, 2022, 132368.
- Linlin Bai, Liu Wang, Shuqin Huang, Rong Bai, Xucong Lv, Liping Sun, Fang Zhang*, Xiahong Xu*. Rapid, Visual, and Sequence-Specific Detection of Salmonella in Egg Liquid with vis-NEAA, a CRISPR/Cas12 Empowered New Strategy. Journal of Agricultural and Food Chemistry, 2022.
- Fang Zhang, Chenshan Gao, Linlin Bai, Yiquan Chen, Shuying Liang, Xucong Lv, Jinyuan Sun, Shaoyun Wang*. Dual-color blending based visual LAMP for food allergen detection: A strategy with enlarged color variation range and contrast. Food Chemistry: X, 2022, 13: 100201.
- Xueyun Chen, Liu Wang, Fang He, Ganghui Chen, Linlin Bai, Kaiyu He, Fang Zhang*, and Xiahong Xu*. Label-Free Colorimetric Method for Detection of Vibrio parahaemolyticus by Trimming the G-Quadruplex DNAzyme with CRISPR/Cas12a. Analytical Chemistry, 93 (4)2,14300-14306 (2021)
- Fang Zhang, Juewen Liu*. Interactions of the Cocaine and Quinine Aptamer with Gold Nanoparticles under the Dilute Biosensor and Concentrated NMR Conditions, Langmuir,2021, 37(40):11939-11947
- Fang Zhang, Juewen Liu*. Label‐Free Colorimetric Biosensors Based on Aptamers and Gold Nanoparticles: A Critical Review. Analysis & Sensing,1,30-43 (2021)
- Fang Zhang, Po-Jung Jimmy Huang and Juewen Liu*. Sensing Adenosine and ATP by Aptamers and Gold Nanoparticles: Opposite Trends of Color Change from Domination of Target Adsorption Instead of Aptamer Binding. ACS Sensors, 5, 2885–2893 (2020)
- Fang Zhang, Xixi Cai, Lan Ding, Shaoyun Wang*. Effect of pH, ionic strength, chitosan deacetylation on the stability and rheological properties of O/W emulsions formulated with chitosan/casein complexes. Food Hydrocolloids, 111, 106211 (2021)
- Xixia Liu, Fan He, Fang Zhang, Zijie Zhang, Zhicheng Huang and Juewen Liu*. Dopamine and Melamine Binding to Gold Nanoparticles Dominates Their Aptamer-based Label-free Colorimetric Sensing. Analytical Chemistry, 92, 9370–9378 (2020)
- Po-Jung Jimmy Huang, Jeffy Yang, Kellie Chong, Qianyi Ma, Miao Li, Fang Zhang, Woohyun J. Moon, Guomei Zhang and Juewen Liu*. Good’s buffers have various affinities on gold nanoparticles regulating fluorescent and colorimetric DNA sensing. Chemical Science, 11, 6795-6804 (2020)
- Fang Zhang, Biwu Liu, Anand Lopez, Shaoyun Wang* and Juewen Liu*. Opposite salt-dependent stability of i-motif and duplex reflected in a single DNA hairpin nanomachine. Nanotechnology, 31, 195503 (2020)
