Academic Staff
- TU318
- +852 3400 8678
- yuyan.zhu@polyu.edu.hk
- Personal Website
ORCID ID
SCOPUS IDResearch Overview
We are studying the role of functional food components/nutrients in ameliorating lipid metabolism disorders, such as obesity and its associated metabolic syndromes, with the focus on adipose tissue.
Education and Academic Qualifications
- Bachelor of Science, Zhejiang University
- Doctor of Philosophy, Purdue University
Academic and Professional Experience
- Editorial Board Member, Journal of Future Foods (2021-present)
- Youth Council member in Society for Metabolic Biology, Biophysical Society of China. (2023-present)
- Review Editor on the Editorial Board of RNA (specialty section of Frontiers in Genetics and Frontiers in Molecular Biosciences)
- Scientific consultant, EFIL Bioscience Incorporation (2021-present)
- Member of Biophysical Society of China
- Member of Physiology Society of China
- Member of American Society for Biochemistry and Molecular Biology
Research Interests
Achievements
- Young Investigator Award (1st place in poster Presentation), 20th diabetes and cardiovascular risk factors - East Meets West Symposium (2018)
- The Bilsland Dissertation Fellowship, Purdue University, USA (2015-2016)
- Purdue Research Foundation Graduate Fellowship, Purdue University, USA (2014)
- National Scholarship, Minister of Education, China (2007)
- Kee-Hong Kim; Yuyan Zhu; US-12274681-B2; Compositions and methods for reducing skin fat (April 2025)
- Kee-Hong Kim; Yuyan Zhu; US-12274682-B2; Compositions and methods for controlling food intake of animal (April 2025)
- Kee-Hong Kim; Yuyan Zhu; US-12257217-B2; Compositions and methods for treating hyperphagia in prader-willi syndrome (March 2025)
- Kee-Hong Kim; Yuyan Zhu; US-11872198-B2; Compositions and methods for regulating body weight and metabolic syndromes (January 2024)
- Kee-Hong Kim; Yuyan Zhu; KR102502031B1; 체중및대사증후군을조절하기위한 조성물및방법 (Febuary 2023)
- Kee-Hong Kim; Yuyan Zhu; US-11065216-B2; compositions and methods for regulating body weight and metabolic syndromes (July 2021)
- Qing Liu∗, Xiaolin Wu∗, Wei Duan, Xiaohan Pan, Martin Wabitsch, Ming Lu, Jing Li, Li-Hao Huang, Zhangsen Zhou, Yuyan Zhu# (2024) “ACAT1/SOAT1 maintains adipogenic ability in preadipocytes by regulating cholesterol homeostasis” Journal of Lipid Research, 65(12), 100680
- Jiang, Haowu and Cui, Huan and Chen, Mengyu and Li, Fengxian and Shen, Xiaolei and Guo, Changxiong Jeff and Hoekel, George E. and Zhu, Yuyan and Han, Liang and Wu, Kangyun and Holtzman, Michael J. and Liu, Qin# (2024) “Divergent Sensory Pathways of Sneezing and Coughing” Cell, ISSN 0092-8674.
- Ming Yang, Qiong Wang, Yuyan Zhu, Kuichuan Sheng, Ning Xiang#, Ximing Zhang# (2023) “Cell culture medium cycling in cultured meat: Key factors and potential strategies” Trends in Food Science & Technology, Volume 138, 564-576.
- Li Su, Quan Xiong, Yuyan Zhu#, and Yunlong Zi# (2022) “A Liquid-Solid Contact Electrification based All-Optical Liquid Flow Sensor for Microfluidic Analysis in Biomedical Applications“. Adv. Funct. Mater. 2022, 2207096.
- Ho Ting Shiu*, Xiaohan Pan*, Qing Liu, KeKao Long, Kenneth King Yip Cheng, Ben Chi-Bun Ko, James Kar-Hei Fang, Yuyan Zhu# (2022) “Dietary exposure to polystyrene nanoplastics impairs fasting-induced lipolysis in adipose tissue from high-fat diet fed mice“. Journal of Hazardous Materials, 440, 2022, 129698, ISSN 0304-3894
- Jung Yeon Kwon*, Jonathan Kershaw*, Chih-Yu Chen, Susan M. Komanetsky, Yuyan Zhu, Xiaoxuan Guo, Phillip R. Myer, Bruce Applegate, Kee-Hong Kim# (2022) “Piceatannol Antagonizes Lipolysis by Promoting Autophagy-Lysosome-Dependent Degradation of Lipolytic Protein Clusters in Adipocytes” Journal of Nutritional Biochemistry,105:108998.
- Yuyan Zhu#, Sora Q. Kim, Yuan Zhang, Qing Liu, Kee-Hong Kim# (2021) “Pharmacological inhibition of acyl-coenzyme A: cholesterol acyltransferase alleviates obesity and insulin resistance in diet-induced obese mice by regulating food intake”. Metabolism: Clinical and Experimental,123:154861.
- HR Steele, Y Xing, Y Zhu, HB Hilley, K Lawson, Y Nho, T Niehoff, L Han# (2021) “MrgprC11+ sensory neurons mediate glabrous skin itch”. Proceedings of the National Academy of Sciences 118 (15) e2022874118.
- Xia, Xin*, Liu, Qing*, Zhu, Yuyan#; Zi, Yunlong# (2020) “Recent advances of triboelectric nanogenerator based applications in biomedical systems“, EcoMat. 2 (4) e12049.
- Zhu, Y., Chen, C.Y., Li, J., Chen, J.-X., Jang, M., Kim, K.-H.# (2018) “In vitro exploration of ACAT contributions to lipid droplet formation during adipogenesis”. Journal of Lipid Research 59(5):820-829.
- Zhu, Y., Hanson, C.E., Liu, Q., and Han, L.# (2017) “Mrgprs activation is required for chronic itch conditions in mice”. Itch 2 (3):9.
- Kim, C.Y.*, Zhu, Y.*, Buhman, K.K., Kim, K.-H.# (2015) “Dietary selenate attenuates adiposity and improves insulin sensitivity in high-fat diet-induced obese mice“. Journal of Functional Foods 17:33-42. (* co-first author).
