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The Transcranial Focused Ultrasound Stimulation (tFUS) System is a state-of-the-art, non-invasive technology designed to precisely modulate brain activity by delivering focused ultrasound waves to targeted neural regions. With millimeter-level accuracy, tFUS supports both research and therapeutic interventions for neurological disorders, enabling deep brain stimulation without the need for surgical procedures. This MRI-compatible system operates at frequencies ranging from 250 kHz to 1000 kHz and achieves focal depths of 60 to 125 mm.

Specifications:

  • Real-time targeting visualization with Brainsight neuronavigation
  • GUI for planning and executing protocols; integrates with k-Plan
  • MRI-compatible package; works with MRI environments
  • Modality compatibility: TMS, EEG, NIRS
  • Multi-planar targeting with two 4-channel transducers (CTX 250/CTX 500, DPX 500)
  • Frequency 250 kHz to 1000 kHz; focal depths 60–125 mm
  • Real-time per-channel power monitoring; automatic air-sonication shutdown
  • Transducer health checks with hydrophone-based QA
  • 100+ pre-loaded protocols; standardized reporting; history and auto-generated report 

 

Applications:

  • Neuromodulation for epilepsy
  • Modulation of movement disorders (Parkinson’s disease, dystonia, essential tremor)
  • Psychiatry and mood disorders (depression, anxiety, PTSD)
  • Chronic pain management
  • Neurorehabilitation after stroke or traumatic brain injury
  • Sleep and circadian research
  • Basic neuroscience and brain mapping
  • Closed-loop stimulation approaches
  • Targeting and monitoring with imaging or recording (EEG, fMRI, etc.)
  • Varied stimulation patterns to study plasticity and network dynamics

Location: ZB218

Charging rate:

PolyU Users (per session): $90

External Users (UGC-funded) (per session): $180

Other External Users (per session): $450

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To use, please go to the URFMS

Equipment in-charge: Dr. Eliza SUN

 

 

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