Research Assistant Professor
- ST525
- +852 2766 4340
- hui-shirley.zhang@polyu.edu.hk
- Healthy Aging and Gerontology
ORCID ID
SCOPUS IDBiography
Dr Hui Zhang (Shirley) received a Bachelor of Engineering degree in Electronic Information Science and Technology from Zhengzhou University in 2012 ,and obtained her postgraduate qualifications in Master of Biomedical Engineering from Peking University in 2015 and a PhD in neuroscience from Hong Kong University in 2019. She underwent postdoctoral fellowship at the HKU Li Ka Shing Faculty of Medicine from 2019 to 2022.
Research by Dr Zhang focused on brain changes in different diseases or during the rehabilitation process using different MRI techniques. Her research includes evaluating the effects on the brain after intranasal insulin administration in Type-2 diabetic patients, small world networks and their relationship with hippocampal Glutamate concentration in healthy adults with the high-risk APOE4 gene, and brain changes in long COVID patients with olfactory dysfunction.
Dr Zhang currently intends to combine multi-modal MRI techniques, such as diffusion tensor imaging (DTI), functional MRI (fMRI) and Positron emission tomography (PET), with artificial intelligence and big data analysis, or other advanced algorithmic techniques to provide insights into the potentially accurate diagnosis and therapy development.
Education and Academic Qualifications
- Bachelor of engineering, Zhengzhou University
- Master of biomedical engineering, Peking University
- Doctor of Philosophy, The Hong Kong University
Research Interests
Research Output
- Hui Zhang, Tom Wai-Hin Chung, Fergus Kai-Chuen Wong, Ivan Fan-Ngai Hung, Henry Ka-Fung Mak. Changes in the intranetwork and internetwork connectivity of the default mode network and olfactory network in patients with covid-19 and olfactory dysfunction. Brain sciences 12.4 (2022): 511.
- Hui Zhang, Pui Wai Chiu, Isaac Ip, Tianyin Liu, Gloria Hoi Yan Wong, You-Qiang Song, Savio Wai Ho Wong, Karl Herrup, Henry Ka Fung Mak. Small-world networks and their relationship with hippocampal glutamine/glutamate (Glx) concentration in healthy adults with varying genetic risk for Alzheimer’s disease. Journal of Magnetic Resonance Imaging 54.3 (2021): 952-961.
- Hui Zhang, Edward S. Hui, Peng Cao, and Henry K.F. Mak. Relationship between amyloid-β deposition and the coupling between structural and functional brain networks in mild cognitive impairment and Alzheimer’s disease patients. Brain Sciences 11.11 (2021): 1535.
- Hui Zhang, Pui Wai Chiu, Isaac Ip, Tianyin Liu, Gloria Hoi Yan Wong, You-Qiang Song, Savio Wai Ho Wong, Karl Herrup, Henry Ka Fung Mak. Asymmetric left-right hippocampal glutamatergic modulation of cognitive control in APOE-isoform subjects is not related to neuroinflammation. European Journal of Neuroscience 54.4 (2021): 5310-5326.
- Hui Zhang & Tom Wai-Hin Chung, Fergus Kai-Chuen Wong, Siddharth Sridhar, Kwok-Hung Chan, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Ivan Fan-Ngai Hung, Henry Ka-Fung Mak. Neurosensory rehabilitation and olfactory network recovery in COVID-19-related olfactory dysfunction. Brain sciences 11.6 (2021): 686.
- Zhou, Diange, Shijie Zhang, Hui Zhang, Long Jiang, Jue Zhang, and Jing Fang. A novel method of evaluating knee joint stability of patients with knee osteoarthritis: multiscale entropy analysis with a knee-aiming task. Scientific reports 7, no. 1 (2017): 354.
- Hui Zhang, Ying Hao, Bradley Manor, Peter Novak, William Milberg, Jue Zhang, Jing Fang, and Vera Novak. Intranasal insulin enhanced resting-state functional connectivity of hippocampal regions of in type 2 diabetes. Diabetes. 64.3 (2015): 1025-1034.
