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PolyU develops portable nucleic acid testing device for COVID-19 to enable fast and accurate results on-site

Over the past two years, the COVID-19 pandemic has imposed a tremendous impact on society as well as on the daily lives of individuals. In the “post-pandemic” era, it is important to strengthen efforts in research and development of drug and vaccine, while also continuing to uphold high standards of personal and environmental hygiene management. Therefore, an accurate and convenient COVID-19 testing method could certainly help ease the stress of post-pandemic life.

13 Apr, 2022

2nd round MOOC

The second run of self-paced MOOC on Interdisciplinary Innovations for Population Ageing

Population ageing is a global phenomenon profoundly affecting the well-being of communities. Disciplines such as Social Sciences, Design, and Engineering offer unique, insightful innovations for ageing societies. Along with providing solutions catering to their professional niche, these disciplines achieve creative and practical innovations through interdisciplinary collaboration. This course intends to explore and examine the process of incubating innovations in these three disciplines and help the learners to appreciate the synergy created when working toward innovations by adopting an interdisciplinary approach.    Welcome to the world of active ageing! The second run of the course has already started on 1 Apr, 2022. Learn more about this course and get enroll by checking the links below.   Register NOW, and get your 100% off coupon by contacting us at innovage.mooc@polyu.edu.hk. (50 coupons are available on a first-come, first-serve basis)   Second Run of the MOOC will last from 1 Apr to 31 Aug, 2022 (Due date for enrollment and upgrade: 27 May 2022, HKT 12:00 p.m.)   Course Enrollment: https://www.edx.org/course/interdisciplinary-innovations-for-population-aging   Course Trailer: https://drive.google.com/file/d/12U0bgpqufY8VtW-6kEVvRMtz45CEsBQj/view?usp=sharing

11 Apr, 2022

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Outstanding Alumni Award of PolyU Department of Biomedical Engineering

We are pleased to present the “Outstanding Alumni Award of PolyU Department of Biomedical Engineering 2022” to two distinguished graduates in recognition of their Professional Achievement and significant contributions to the Department, PolyU and the community. Their remarkable achievements and valuable contributions have earned them the well-deserved honour. Congratulations to the following awardees!   “Outstanding Alumni Award in Professional Achievement of PolyU, Department of Biomedical Engineering” Mr. WONG Kai Yuen, Billy  Master of Science in Health Care (Healthcare Technology) / 2008 The Hong Kong Polytechnic University   “Outstanding Young Alumni Award in Professional Achievement of PolyU, Department of Biomedical Engineering” Ir. LEUNG Cristina  Bachelor of Science in Biomedical Engineering / 2007 The Hong Kong Polytechnic University  

25 Mar, 2022

123 (2)

Dr Youhua TAN and Dr Chunyi WEN received the Faculty of Engineering (FENG) Research Grant Achievement Award for 2020

We are proud to announce that our Professors, Dr. Chunyi Wen & Dr. Youhua Tan received the Faculty of Engineering (FENG) Research Grant Achievement Award for 2020 in recognition of their great efforts and contributions in securing external competitive research grants. All of them have led and participated in a number of multidisciplinary research projects in recent years. We have conducted an interview to let you know more about their achievements and research.  Dr. Chunyi Wen “During the tough period in COVID-19, you should never give up pursuing your dream in science advances and technical innovations. Now we can see the light at the other end of the tunnel to get through this pandemic. Meanwhile, we shall prepare and equip ourselves with knowledge and capability to battle for the next disaster and pandemic in near future.” Dr. Chunyi Wen Associate professor Department of Biomedical Engineering   Q: Dr. Wen, congratulations on your achievements in the research field and outstanding performance in securing research grants. Could you tell us your feelings about applying for these funds, is it tough? A: The research grant application is highly competitive in Hong Kong. We are so lucky to receive the support from RGC, HMRF and ITF. It is our honor but also our responsibility to deliver what we have proposed. Q: To let our students know more about your research field, could you please briefly introduce the research areas of your group? A: We are targeting the ageing and age-related diseases as a whole, and we chose osteoarthritis as a point of breakthrough because it occurs at the early stage of ageing and link with many other age-related diseases in late life. It might provide us a new insight to understand ageing process. Q: Could you simply share something with us that made you so interested in osteoarthritic? A: My research centers are about ageing and age-related diseases, particularly skeletal ageing including osteoarthritis and osteoporosis. What I and my team are interested in is not a single disease, osteoarthritis. We deploy cutting-edge technologies including human organoid, single-cell sequencing, live-cell imaging empowered by machine learning-empowered computing vision to probe and map ageing process, at its onset and its early stage. Q: You are also doing research related to COVID-19, what is your view on the current fifth wave of COVID-19? A: Our knowledge about COVID-19 is growing and our arsenal combating SARS-Cov-2 is enriching including vaccine and anti-virus drugs. Also, there is a growing body of interest in how to mitigate the severe cases of COVID-19. We are working on this direction together with the HKU microbiology team. Also, we are paying attention to long COVID symptoms affecting bone and joint.  Q: Finally, do you have any advice or guidance for our students? A: During the tough period in COVID, we should never give up pursuing our dream in science advances and technical innovations. Now we can see the light at the other end of the tunnel to get through this pandemic. Meanwhile, we shall prepare and equip ourselves with knowledge and capability to battle for the next disaster and pandemic in near future. Dr. Youhua Tan “I hope that all of our BME students have an inclusive mindset so that they can look at the same problem from different perspectives, such as, studying a disease from the engineering point of view. This could be one unique advantage of our BME students over others. I also wish all BME students to be healthy and optimistic during the current pandemic.” Dr. Youhua Tan Associate professor Programme Coordinator (MSc in BME) Department of Biomedical Engineering   Q: Dr. Tan, firstly, congratulations on your achievements in the research field and securing external competitive research grants. Do you have any unforgettable things in applying for the grants? A: To push the boundary of the relevant research field, all researchers are required to propose new ideas/hypotheses and explore new things, which need financial support from the funding bodies. The application of research grants in Hong Kong is always competitive, therefore we need to keep trying to apply for new research grants. So far, we have received support from RGC, NSFC, HMRF, and Shenzhen Government. Q: Could you please briefly introduce the research topics of your group? A: My research group mainly focuses on investigating the roles of mechanics in tumor metastasis, including tumor cell mechanics and malignancy, mechanically heterogeneous tumor tissue and preferential metastasis, and tumor cell stiffness for mechanotargeting. Recent advance in the mechanobiology tools has been utilized to tackle these key problems, such as atomic force microscope, tumor organoid, traction force microscope, ultrasound elastography, etc. Q: As you are the expert in mechanobiology and tumors, are you interested in studying sars-cov-2? A: Recent evidence has shown the involvement and significance of mechanics in various diseases, including cancer, aging, malaria, etc. We believe that mechanical force may also play important role in COVID. We are interested in this currently prevalent disease but have not started to investigate it yet.Q: This year (2022) will be the 10th anniversary of BME. As programme coordinator (MSc in BME), could you tell us about your expectations for the future development of BME, and some good points of our MSc programme? A: Since the nature of BME is multidisciplinary, I expect that more and more new fields and directions will emerge by combining engineering and other disciplines, especially those related to healthcare. To keep up with the pace of the new development, we have recently proposed two new specialisms into our MSc programme: Rehabilitation Engineering and Digital Health, which are pending for approval by the University. We believe the addition of these new specialisms will push the further development of our MSc programme and the department. Q: Finally, do you have any advices or guidances for our students? A: I hope that all of our BME students have an inclusive mindset so that they can look at the same problem from different perspectives, such as, studying a disease from the engineering point of view. This could be one unique advantage of our BME students over others. I also wish all BME students to be healthy and optimistic during the current pandemic. Credit to: Jun LIU (Postgraduate in Biomedical Engineering)  

11 Mar, 2022

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Ir Prof. Yongping ZHENG Honoured with President’s Awards 2021

We are pleased to announce Ir Prof. Yongping Zheng, Chair Professor of Biomedical Engineering has been awarded the Individual Award – Knowledge Transfer: Industry under the President’s Awards 2021 for his outstanding achievement in knowledge transfer. The University recognises the distinguished accomplishments and contributions of staff members through the President’s Awards for Outstanding Achievement. To know more about Prof. Zheng: https://polyu.hk/haHND 

10 Feb, 2022

lab visit

Lab visit and Meeting with Double Medical Technology Inc

The co-founder/owner of 大博医疗 (Double Medical Technology Inc, www.double-medical.com), Dr. LIN Zhijun(林志軍)visited our labs and department on 28 Jan 2022. Dr. Lin is interested in investing or collaborating on new research and development that leads to translation in healthcare, especially those related to bones, biomechanics, and rehabilitation.

4 Feb, 2022

Msc banner

Application Now Open:Master of Science in Biomedical Engineering

26 Jan, 2022

xin and mo

Prof YANG Mo and Dr ZHAO Xin received RGC Collaborative Research Fund 2021/22

Our warmest congratulations to Prof YANG Mo and Dr ZHAO Xin who receive RGC Collaborative Research Fund in 2021/22. Name Proposal Title RGC Amount Awarded Prof YANG Mo An upright multiphoton microscope for intravital imaging and optogenetic studies HKD 3,910,000 Dr ZHAO Xin Development of high-resolution 3D scaffolds with biomimetic triply periodic minimal surface structure for bone tissue repair HKD 4,185,000               In this Exercise, PolyU submitted 50 CRF preliminary proposals with PolyU staff as PC. After a long and rigorous selection procedure, 5 proposals (including 3 Research Equipment Grant and 2 Research Project Grant) were supported by RGC with a total amount of awarded funding of $24.109 million. About the projects Prof YANG Mo - An upright multiphoton microscope for intravital imaging and optogenetic studies An upright multiphoton microscopy system will be established with intravital imaging and optogenetic stimulation function. An interdisciplinary team with background in neuroscience, visual science, neural rehabilitation and nanobiotechnology will collaborate together. The proposed equipment will help the development of new engineering approaches based on novel functional bioprobes to realise simultaneous deep-brain imaging and optogenetic studies, which can be used to study the fundamental problems in neuroscience, visual science and neuro-rehabilitation, enable deeper understanding of neuronal behaviour in vivo, elucidate the cellular and molecular mechanisms underlying a broad spectrum of neuronal diseases, and tackle human health-related challenges. Dr ZHAO Xin - Development of high-resolution 3D scaffolds with biomimetic triply periodic minimal surface structure for bone tissue repair Surface topology has demonstrated significant influence on regulating stem cell behaviors, functions and regenerating bone tissues. Notably, the hyperboloid structure is one that many species around the globe (e.g., coral calcification, leaves’ photosynthesis, mammalian trabecular bone) have adopted due to evolutionary advantages related to their amplified surface area, curvature, and energy dissipation. To recapitulate the architectural marvel of the hyperboloid structure, we propose a three-dimensional (3D) Triply Periodic Minimal Surface (TPMS) scaffolds with varying Gaussian curvatures to embody a trabecular bone mimicking hyperboloidal topography. TPMS is a crystallographic symmetric and lattice-based structure in three directions, with excellent surface area, porosity and interconnectivity for both mesenchymal stem cell (MSC) adhesion/migration and vascular infiltration, effectively achieving osteogenesis-angiogenesis coupling through activation of many cell signaling pathways. Ultrahigh resolution of 3D scaffolds with TPMS structure can be achieved through digital light processing (DLP) printing of β-tricalcium phosphate (β-TCP) slurry alongside addition of various metal ions for modulation of bone mineralization and covering with therapeutic gas nitric oxide generating coatings for enhanced angiogenesis. The resultant TPMS scaffolds will undergo (1) mechanical assessment and characterization to ensure high resolution printing and prevention of stress shielding, (2) in vitro assays for assessment of osteogenic and angiogenic capabilities, and study of underlying molecular mechanisms, and (3) in vivo models to assess the clinical relevancy of the resultant TPMS scaffolds in terms of new bone formation and neovascularization. With diverse talents and rich experience in fabrication of TPMS scaffolds, functionalized surfaces and coatings for osteogenic-angiogenic coupling, the team well demonstrates their capability and previous knowledge to complete the research project. The cell-/growth factor-free nature of the TPMS scaffolds will facilitate clinical translation as it is much closer towards a safe bone graft than implanted alternatives. The successful implementation of the TPMS bone scaffolds will not only benefit patients struggling to recover from long-term bone diseases and fractures, but also initiate the evolution of a revolutionary regeneration concept in biomaterials, i.e., direction of the cell behaviors/functions and tissue formation exclusively through tuning the physical cues, without additional exogenous growth factors, drugs or cytokines. In the long term, commercialization of this project will also reinforce the status quo of the Greater Bay Area as a technological innovative sector, and alleviate the social problems (e.g., growing population with bone diseases/fractures) arising from the aging population of surrounding regions. About RGC CRF For more information about the CRF, please visit https://www.ugc.edu.hk/eng/rgc/funding_opport/crf/ For the full list of funded projects in 2021/22 CRF Exercise, please visit https://www.ugc.edu.hk/eng/rgc/funding_opport/crf/funded%20research/21-22.html

17 Jan, 2022

TSA2122A

Best Teaching Assistant Award for 2021/22 Sem1

The Department is pleased to announce the recipients of the “Best Teaching Assistant Award" in 2021/22 Semester 1:   Awardee List for the Best TA Award for Sem1 of 2021/22 No. Subject Code Subject Title Teaching Assistant(s) for Sem 1 21/22 Subject Leader Supervisor Name Nominated by 1 BME5115 APPLIED BIOSIGNAL PROCESSING JIANG Yizhou Dr. SUN Lei Dr. SUN Lei Teacher and students 2 BME5124 BIOMATERIALS AND TISSUE ENGINEERING ZHANG Cunyu Dr. TAN Youhua Dr. TAN Youhua Teacher and students 3 BME5127 NANOBIOTECHNOLOGY BEI Ho Pan Dr. ZHAO Xin & Dr. WONG Dexter Dr. ZHAO Xin Teacher and students 4 BME5130 ADVANCED PROSTHETICS AND ORTHOTICS LIU Shan Dr. WONG Man Sang Dr. WONG Man Sang Teacher and students 5 BME5155 RESEARCH METHODS & BIOSTATISTICS ZOU Zhou Dr. WEN Chunyi Dr. WEN Chunyi Teacher and students 6 BME21120 FUNDAMENTALS OF BIOMEDICAL INSTRUMENTATION I HO Kwun Hei Willis Prof. YANG Mo Prof. YANG Mo Teacher and students 7 BME21111 BIOMEDICAL ENGINEERING RESEARCH & DESIGN STUDIES I ZHANG Ruolin Dr. LAU Hin Chung Prof. YANG Mo Students 8 BME6050 RESEARCH METHODOLOGY IN BIOENGINEERING AND HEALTHCARE ZHANG Guoxin Dr. WONG Wai Chi Duo Prof. ZHANG Ming Students 9 BME1D02 WEARABLE HEALTHCARE AND FITNESS DEVICES FOR EVERYONE YANG De Prof. ZHENG Yongping & Dr. CHEUNG James Prof. ZHENG Yongping Teacher 10 BME1D02 WEARABLE HEALTHCARE AND FITNESS DEVICES FOR EVERYONE TAM Yiu Chau Prof. ZHENG Yongping & Dr. CHEUNG James Dr. CHEUNG Wai Chung James Teacher 11 BME1D02 WEARABLE HEALTHCARE AND FITNESS DEVICES FOR EVERYONE THARU Niraj Singh Prof. ZHENG Yongping & Dr. CHEUNG James Prof. ZHENG Yongping Teacher 12 BME1D03 TECHNOLOGIES FOR SMART AGEING ZHANG Yuqi Dr. WEN Chunyi Dr. WEN Chunyi Teacher 13 BME1D04 SKIN-CARE TECHNOLOGIES: PRINCIPLES, APPLICATIONS AND SAFETY LYU Shang Dr. ZHAO Xin & Dr. WONG Dexter Dr. ZHAO Xin Teacher 14 BME1D04 SKIN-CARE TECHNOLOGIES: PRINCIPLES, APPLICATIONS AND SAFETY RAO Jingdong Dr. ZHAO Xin & Dr. WONG Dexter Dr. ZHAO Xin Teacher 15 BME31116 BIOSIGNAL PROCESSING CHENG Shengfu Dr. LAI Puxiang Dr. LAI Puxiang Teacher 16 BME31125 BIOMECHANICS CHEN Fei Prof. ZHANG Ming & Dr. WANG Annie Prof. ZHANG Ming Teacher 17 BME32104 BELOW-KNEE PROSTHETICS HU Mingyu Dr. KOBAYASHI Toshiki Dr. KOBAYASHI Toshiki Teacher 18 BME32115 BIOSENSORS: THEORIES AND BIOMEDICAL APPLICATIONS TAN Xiaoxuan Dr. LEE Thomas Dr. LEE Thomas Teacher 19 BME32140 CLINICAL ENGINEERING HUANG Yingying Prof. POON Albert Prof. YANG Mo Teacher 20 BME3S02 ASSISTIVE TECHNOLOGIES: SERVICE LEARNING TOWARDS THE ELDERLY AND DISABLED ZHU Tanglong Dr. MA Zonghao Dr. MA Zonghao Teacher 21 BME3S02 ASSISTIVE TECHNOLOGIES: SERVICE LEARNING TOWARDS THE ELDERLY AND DISABLED ZUO Jingjing Dr. MA Zonghao Dr. MA Zonghao Teacher 22 BME42129 NEUROENGINEERING ZHOU Sa Dr. HU Xiaoling Dr. HU Xiaoling Teacher

13 Jan, 2022

faculty award

Faculty Awards for Outstanding Achievement 2021

Congratulations to the following staff members on receiving the Faculty Awards for Outstanding Achievement 2021. Our hearty congratulations to them for their achievements! Category of Award Category of Award Category of Award Individual Awards - Services Outstanding Awards Prof. Yongping ZHENG Team Awards - Services Outstanding Awards Dr. Hin Chung LAU Individual Awards - Teaching Merit Awards Dr. WONG Man Sang Individual Awards - Research and Scholarly Activities: Outstanding Researcher Merit Awards Dr. WEN Chunyi Individual Awards - Research and Scholarly Activities: Outstanding Young Researcher Merit Awards Dr. Youhua TAN

21 Dec, 2021

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