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許鈞量博士

郭氏集團老齡化及神經影像學青年學者,助理教授,Presidential Young Scholar

PhD (UBC), MSc (UBC), BSc (UBC)

簡歷

許博士於英屬哥倫比亞大學畢業獲得康復療科學博士學位。後,許博士取得加拿大衛生研究院(CIHR的研究獎學金,在享負名的哈佛醫學院Hinda and Arthur Marcus老齡化研究所接受博士後培訓。

博士主要利用磁共振成像來進行他的工作。他的研究興趣包括:1) 了解功能障礙的潛在神經基礎,及其與老年臨床人群認知和活動能力的關係;2) 識別評估與中樞神經系統相關的干預措施,藉此促進臨床人群的認知和活動能力。具體來說,博士結合使用先進的神經影像技術來檢查認知功能和活動能力受損的神經特徵,並研究如何通過特定的干預措施調節這些受損況。博士與各臨床人群作,包括患有中風、輕度認知障礙和行動不便的老人。

學歷

  • Doctor of Philosophy in Rehabilitation Sciences, University of British Columbia
  • Master of Science in Rehabilitation Sciences, University of British Columbia
  • Bachelor of Science, University of British Columbia

研究興趣

  • 老齡化
  • 認知障礙
  • 行動障礙
  • 神經影像
  • 磁共振成像

研究成果

    • Hsu CL, Best JR, Voss MW, Handy TC, Beauchet O, Lim C, Liu-Ambrose T. Functional neural correlates of slower gait among older adults with mild cognitive impairment. J Gerontol A Biol Sci Med Sci. 2018 Feb 17. doi: 10.1093/gerona.gly027
    • Hsu CL, Best JR, Davis JC, Nagamatsu LS, Wang S, Boyd LA, Hsiung RGY, Voss MW, Eng JJ, Liu-Ambrose T. Aerobic exercise promotes executive functions and impacts functional neural activity among older adults with vascular cognitive impairment. BJSM. 2017 Apr 21. pii: bjsports-2016-096846. doi: 10.1136/bjsports-2016-096846
    • Hsu CL, Best JR, Chui BK, Voss MW, Handy TC, Bolandzadeh N, Liu-Ambrose T. Structural neural correlates of falls status and subsequent decline in executive functions: A 12-month prospective study. Exp Geronto. 2016 Apr 11;80:27-35. doi: 10.1016/j.exger.2016.04.001
    • Falck RS, Hsu CL, Silva NCBS, Li LC, Best JR, Liu-Ambrose T. The independent associations of physical activity and sleep with neural activity during an inhibitory task: Cross-sectional results from the MONITOR-OA study. J Sleep Res. 2022 Jul 12:e13692. doi: 10.1111/jsr.13692
    • Boa Sorte Silva NC, Dao E, Hsu CL, Tam RC, Stein R, Alkeridy W, Laule C, Vavasour IM, Liu-Ambrose T. Myelin content and gait impairment in older adults with cerebral small vessel disease and mild cognitive impairment. Neurobiol Aging. 2022 Jul 20;119:56-66. doi: 10.1016/j.neurobiolaging.2022.03.020
    • Crockett RA, Falck RS, Dao E, Hsu CL, Tam R, Alkeridy W, Liu-Ambrose T. Sweat the fall stuff: Physical activity moderates the association of white matter hyperintensities with falls risk in older adults. Front Hum Neurosci. 2021 May 21;15:671464. doi: 10.3389/fnhum.2021.671464. PMID: 34093153; PMCID: PMC8175638.
    • Crockett RA, Hsu CL, Dao E, Tam R, Eng JJ, Handy TC, Liu-Ambrose T. Painting by lesions: White matter hyperintensities disrupt functional networks and global cognition. Neuroimage. 2021 Apr 18:118089. doi: 10.1016/j.neuroimage.2021.118089. Epub ahead of print. PMID: 33882347.
    • Ten Brinke LF, Hsu CL, Erickson KI, Handy TC, Liu-Ambrose T. Functional connectivity and response inhibition: Effects of an 8-week randomized controlled trial of computerized cognitive training. J Alzheimers Dis. 2021;80(4):1525-1537. doi: 10.3233/JAD-200844. PMID: 33720882.
    • Liu-Ambrose T, Davis JC, Best JR, Dian L, Madden K, Cook W, Hsu CL, Khan KM. Effect of a home-based exercise program on subsequent falls among community-dwelling high-risk older adults after a fall: A randomized clinical trial. JAMA. 2019 Jun 4;321(21):2092-2100. doi: 10.1001/jama.2019.5795

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