Supporting Staff
Dr Aaron XU
Senior Scientific Officer
BSc (PolyU), PhD (HKU)
- ST815
- 3400 3468
- cheng-aaron.xu@polyu.edu.hk
Biography
Dr XU received his BSc in Biology from The Hong Kong Polytechnic University and his PhD from The University of Hong Kong. Prior to joining the Department of Rehabilitation Sciences at The Hong Kong Polytechnic University, he worked in Shenzhen University and The University of Hong Kong and participated in a number of research projects funded by the NSFC and HMRF. He works in the field of ageing, diabetes and cardiovascular disease especially in mitochondria ageing, adipose ageing, haematopoietic stem cells ageing. He has substantial experience in animal experiments, project management, research grant proposals and research paper preparation.
Education and Academic Qualifications
- PhD, The University of Hong Kong
- Bachelor of Applied Biology with Biotechnology, The Hong Kong Polytechnic University
Research Interests
Research Output
- Liu Z., Qian M., Tang X., Hu W., Sun S., Li G., Zhang S., Meng F., Cao X., Sun J., Xu C., Tan B., Pang Q., Zhao B., Wang Z., Guan Y., Ruan X. and Liu B. (2019). SIRT7 couples light-driven body temperature cues to hepatic circadian phase coherence and gluconeogenesis. Nature Metabolism 1:1141-1156
- Hampe, L., Xu, C., Harris, P.W.R., Chen, J., Liu, M., Middleditch, M., Radjainia, M., Wang, Y., and Mitra, A.K. (2017). Synthetic peptides designed to modulate adiponectin assembly improve obesity-related metabolic disorders. British Journal of Pharmacology 174, 4478-4492.
- Xu, C., Cai, Y., Fan, P., Bai, B., Chen, J., Deng, H.B., Che, C.M., Xu, A., Vanhoutte, P.M., and Wang, Y. (2015). Calorie Restriction Prevents Metabolic Aging Caused by Abnormal SIRT1 Function in Adipose Tissues. Diabetes 64, 1576-1590.
- Xu, C., Bai, B., Fan, P., Cai, Y., Huang, B., Law, I.K., Liu, L., Xu, A., Tung, C., Li, X., et al. (2013). Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in mice. American journal of translational research 5, 412-426.
- Wang, Y., Xu, C., Liang, Y., and Vanhoutte, P.M. (2012). SIRT1 in metabolic syndrome: where to target matters. Pharmacology & therapeutics 136, 305-318.
