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Introduction:

Ion Mobility

 Waters Synapt G2-Si High Definition Ion Mobility Mass Spectrometer is a high resolution mass spectrometer coupled with an ion mobility separation for chemical analysis. It is particularly useful for the analysis of isomers, conformers and isobaric compounds. When the MS system is combined with the hydrogen deuterium exchange system, it enables the measurement of protein conformation, protein dynamics and protein ligand interactions.

Specifications:

Waters Synapt G2-Si High Definition Ion Mobility Mass Spectrometer

  • Ion Source:
    • Electrospray ionization (ESI)
    • nanoelectrospray ionization (nano ESI)
    • Matrix assisted laser desorption / ionization (MALDI) with imaging function
    • Desorption electrospray ionization (DESI) with imaging function
    • Direct analysis in real time (DART)
    • Atmospheric solid analysis probe (ASAP)
    • Atmospheric pressure chemical ionization (APCI)
    • Atmospheric pressure photoionization (APPI)
  • Scan modes:
    • Time-of-flight (TOF) mode
    • High definition (HD) MS mode (with ion mobility separation)
  • Fragmentation techniques in MS/MS:
    • Collision induced dissociation (CID)
    • Electron transfer dissociation (ETD)
  • Mass range:
    • m/z 20-100,000
  • Mass resolution: 60,000 FWHM at m/z 956
  • Ion mobility separation resolution: m/z 36
  • Mass accuracy:
    • Less than 1ppm RMS using internal lock mass correction

 

Notes to users:

Please refer to UCEA Charging Scheme for details of equipment utilization charge.

 

Charging:

Direct infusion: $100 / hr (internal users); $200 / hr (collaborators); $1000 / hr (external users)
LC/MS: $300 / 4hr (internal users); $600 / 4hr (collaborators); external users please enquiry
LC/MS: $500 / 8hr (internal users); $1000 / 8hr (collaborators); external users please enquiry
LC/MS: $1000 / 24hr (internal users); $2000 / 24hr (collaborators); external users please enquiry

 

Booking:

Please visit our University Research Facility Management System (URFMS) website for registration, training request and booking arrangement.

 

Contact Information:

Location: W711, Block W, The Hong Kong Polytechnic University
Equipment-in-charge: Dr. Sirius TSE (Office: U514)
Email: sirius.tse@polyu.edu.hk
Telephone: 3400 8878

 

User Fees:

Default Collaborators External User
Direct infusion
$100.00 / hr $200.00 / hr $ 1000.00 / hr

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