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Innovating for the future: Advancing toxicity testing technologies for urban health

25 Feb 2026

Research and Innovation

Air pollution is a leading global health risk, with PM₂.₅ fine particulate matter posing a particularly severe threat to public health. Prof. LI Xiangdong, Dean of Faculty of Construction and Environment, Chair Professor of Environmental Science and Technology and Ko Jan Ming Professor in Sustainable Urban Development of The Hong Kong Polytechnic University (PolyU) leads a team focused on identifying the key toxic components and emission sources of PM₂.₅. These fine particles are known to contribute to both acute and chronic health conditions, especially chronic obstructive pulmonary disease and ischemic heart disease, and pose long-term risks to vulnerable populations.

To foster cross-disciplinary collaboration, the team regularly organises workshops, bringing together local and international experts to discuss health issues related to PM₂.₅ and share the latest scientific findings and policy perspectives. Leveraging a global monitoring network and advanced analytical technologies, the team investigates the chemical composition, toxicity, formation, and emission pathways of PM₂.₅ in urban settings.

In terms of methodology, the PolyU researchers have developed a range of innovative toxicity testing techniques, including the use of cell lines, animal models, and epidemiological data from human populations. These approaches enable multi-scale assessments of health risks associated with PM₂.₅. This integrated research framework not only informs future directions of PM₂.₅ studies but also offers evidence-based recommendations to governments and international organisations to develop more effective air quality policies to safeguard public health.

 

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