Academic Staff
- TU326
- +852 3400 8840
- fsnxu.chen@polyu.edu.hk
ORCID ID
SCOPUS IDResearch Overview
Dr. Chen’s research is mainly focused on the epidemiology, mechanism, and lifestyle intervention of cardiometabolic diseases, especially metabolic dysfunction-associated steatotic liver disease (MASLD).
Education and Academic Qualifications
- Bachelor of Medicine, Sun Yat-sen University
- Doctor of Medicine, Sun Yat-sen University
Research Interests
Achievements
(* Corresponding author; # Co-first author)
- Xue H#, Wang L#, Sun D, Wu Y, Yu C, Huang Y, Chan SO, Ling W, Lv J, Li L, Chen X *, Pang Y *, Yu C *. Associations of Alcohol Consumption and Genetic Predisposition to Hepatic Steatosis With Liver-Related Events: Results From Large Population-Based Cohort Studies. Gastroenterology. 2025 May 14:S0016-5085(25)00712-7.
- Xue H, Wang L, Wu Y, Liu X, Jiang J, Chan SO, Chen X *, Ling W *, Yu C *. Association of moderate alcohol intake with the risks of cirrhosis and steatotic liver disease: Results from a large population-based cohort study. Clin Nutr. 2024 Dec;43(12):75-83.
- Chen X#, Chen S#, Pang J#, Huang R, You Y, Zhang H, Xiao J, Xue H*, Ling W*. Hepatic steatosis aggravates atherosclerosis via small extracellular vesicle-mediated inhibition of cellular cholesterol efflux. J Hepatol. 2023 Sep 5; S0168-8278(23)05077-8.
- Chen S#, Pang J#, Huang R#, You Y, Zhang H, Xue H*, Chen X*. Associations of Macronutrients Intake with MRI-Determined Hepatic Fat Content, Hepatic Fibro-inflammation, and NAFLD. J Clin Endocrinol Metab. 2023 Jun 8; dgad346.
- Chen S, Pang J, Huang R, Xue H*, Chen X*. Association of MAFLD with end-stage kidney disease: a prospective study of 337,783 UK Biobank participants. Hepatol Int. 2023 Jun;17(3):595-605.
- Zhang P, Chen K, He T, Guo H*, Chen X*. Coenzyme Q10 supplementation improves adipokine profile in dyslipidemic individuals: a randomized controlled trial. Nutr Metab (Lond). 2022 Mar 3;19(1):13.
- Xue H#, Chen X#, Yu C, Deng Y, Zhang Y, Chen S, Chen X, Chen K, Yang Y*, Ling W*. Gut Microbially Produced Indole-3-Propionic Acid Inhibits Atherosclerosis by Promoting Reverse Cholesterol Transport and Its Deficiency Is Causally Related to Atherosclerotic Cardiovascular Disease. Circ Res. 2022 Aug 19;131(5):404-420.
- Chen X, Chen S, Pang J, Tang Y, Ling W*. Are the different MAFLD subtypes based on the inclusion criteria correlated with all-cause mortality? J Hepatol. 2021 Jun 18:S0168-8278(21)00421-9.
- Chen X, Sun X, Shen T, Chen Q, Chen S, Pang J, Mi J, Tang Y, You Y, Xu H, Ling W*. Lower adropin expression is associated with oxidative stress and severity of nonalcoholic fatty liver disease. Free Radic Biol Med. 2020 Nov 20; 160:191-198
- Chen X#, Xue H#, Fang W, Chen K, Chen S, Yang W, Shen T, Chen X, Zhang P, Ling W*. Adropin protects against liver injury in nonalcoholic steatohepatitis via the Nrf2 mediated antioxidant capacity. Redox Biol. 2019 Feb; 21:101068.
