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Prof. Wing-tak Wong
Open Platform for University Scholars

Prof. Wong Wing-tak

Deputy President and Provost & Chair Professor of Chemical Technology

Education and Academic Qualifications

  • Bachelor of Science, The University of Hong Kong
  • Master of Philosophy, The University of Hong Kong
  • Doctor of Science, University of Cambridge
  • Doctor of Philosophy, University of Cambridge

Professional Qualifications

  • Fellow of Royal Society of Chemistry
  • Chartered Scientist
  • Chartered Chemist

Research Overview

My research areas mainly include the development of molecular probes for biological imaging and X-ray crystallography. A wide range of lanthanide-based materials have been developed for optical and magnetic resonance imaging applications while their fundamental properties are thoroughly investigated for performance optimization.

Research Interests

  • Lanthanide Complexes for MR Imaging
  • Molecular Probes for Chemical Imaging
  • Nanostructures for Ion Sensing
  • X-Ray Crystallography

Achievements

  • 2000                Doctor of Science, University of Cambridge, UK
  • 2001                Outstanding Young Researcher Award, HKU
  • 2002                Croucher Senior Research Fellowship, The Croucher Foundation
  • 2003                Outstanding Research Student Supervisor Award, HKU
  • 2008                Outstanding Researcher Award, HKU
  • 2012                Outstanding Achievement Award in Scientific Research for Institution of Higher Education of China
  • 2015                Gold Award, 43rd International Exhibition of Inventions of Geneva
  • 2020         Ministry of Education Higher Education Outstanding Scientific Research Output Award, Second-class Award in Natural Science
     
  • Wong WT, Chan WY "Optimized relaxivity and specificity hepatobiliary MRI contrast agent". U.S. Patent 7,767,196. 3 Aug 2010.
  • Yung KF, Wong WT, Kwong TL "Methods and catalysts for green biodiesel production from unrefined low grade feedstock". U.S. Patent 9,694,350. 4 Jul 2017.
  • Yung KF, Wong WT, Kwong TL "Methods and catalysts for green biodiesel production from unrefined low grade feedstock". European Patent 3274298. 9 Oct 2019.
  • Yung KF, Wong WT, Kwong TL, Lau PC "Catalyst and method for biodiesel production from unrefined low-grade oil and crude aqueous alcohols". U.S. Patent 20180265446A1. 
  1. Lui KH, Li S, Lo WS, Gu Y, Wong WT. In vivo photoacoustic imaging for monitoring treatment outcome of corneal neovascularization with metformin eye drops Biomedical Optics Express. 2021; 12(6): 3597-3606.
  2. Li S, Lui KH, Li X, Fang X, Lo WS, Gu Y, Wong WT. pH-triggered poly(ethylene glycol)-poly(lactic acid)/glycolic acid)/croconaine nanoparticles-assisted multiplexed photoacoustic imaging and enhanced photothermal cancer therapy ACS Applied Bio Material 2021; 4: 4152-4164.
  3. Fang X, Wu X, Li Z, Jiang L, Lo W, Chen G, Gu Y, Wong WT. Biomimetic anti-PD-1 peptide-loaded 2D FePSe3 nanosheets for efficient photothermal and enhanced immune therapy with multimodal MR/PA/thermal imaging. Advanced Science, 2020; 8(2): 2003041.
  4. Lai WF, Wong WT, Rogach AL. Development of copper nanoclusters for in vitro and in vivo theranostic applications Advanced Materials. 2020; 32: 1906872-1906893.
  5. Jiang L, LungHL , Huang T, Lan R, Zha S, Chan LS, Thor W, Tsoi TH, Chau HF Boreström C, Cobb SL, Tsao SW, Bian ZX, Law GL , Wong WT, Tai WCS, Chau WY, Du Y, Tang LHX, Chiang AKS, Middeldorp JM, Lo KW, Mak NK, Long NJ, Wong KL. Reactivation of epstein-barr virus by a dual-responsive fluorescent EBNA1-targeting agent with Zn2+-chelating function.Proceedings of the National Academy of Science. 2019;116(52): 26614-24.
  6. Tsang MK, Wong YT, Tsoi TH, Wong WT, Hao J. Upconversion luminescence sandwich assay for detection of influenza H7 subtype. Advanced Healthcare Materials. 2019; 8(18): 1900575-83.
  7. Dai L, Lo WS, Gu Y, Xiong Q,Wong KL, Kwok WM , Wong WT, Law GL. Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(III) luminescence and unprecedented two-photon excitation properties.
  8. Zhu L., Ma W,Zhang M,Lee MML, Wong WY, Chan BD, Yang Q, Wong WT, Tai WCS, Lee CS. Scalable synthesis enabling multilevel bio-evaluations of natural products for discovery of lead compounds. Nature Communications 2018; 9: 1283.
  9. Yeung CT, Yim KH, Wong HY, Pal R, Lo WS, Yan SC, Wong MYM, Yufit D, Smiles DE, McCormick LJ, Teat SJ, Shuh DK, Wong WT, Law GL. Chiral transcription in self-assembled tetrahedral Eu4L6 chiral cages displaying sizable circularly polarized luminescence. Nature Communications 2017; 8: 1128.
  10. Jiang LJ, LanRF, Huang T, Chan CF, Li HG, Lear S, Zong JY, Wong WY, Lee MML, Chan BD, Chan WL, Lo WS, Mak NK, Lung ML, Lung HL, Tsao SW, Taylor GS, Bian ZX, Tai WCS, Law GL, Wong WT, Cobb SL, Wong KL. EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein-Barr virus.Nature Biomedical Engineering. 2017; 1(4): 0042.
  • Long N. J. Wong WT. "The Chemistry of Molecular Imaging". Indianapolis (IN): Wiley; 2015 (Editor)
  • Wong WT Jin J., "Upconversion Nanoparticles for Bioimaging Application", The Rare Earth Elements, Edited by D.A. Atwood, 2012 Wiley.
  • Wong WT, K.W.Y. Chan "Gadolinium Complexes as MRI Contrast Agents for Diagonsis", Rare Earth Coordination Chemistry-Fundamentals and Applications, Edited by C.H. Huang, 2010 Wiley.
  • Wong WT "Compounds Containing Bonds between Fe and Other Transition Metals, Group 11, 12 elements", Comprehensive Organometallic Chemistry III, Edited by R.H. Crabtree and D.M.P. Mingos, 2006 Elsevier.
  • Wong WT "Heterometallic Ru/Os Containing Compounds", Comprehensive Organometallic Chemistry III, Edited by R.H. Crabtree and D.M.P. Mingos, 2006 Elsevier.

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