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Molecular and Cellular Engineering

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To study the influence of mechanical forces on gene expression by changing nuclear mechanics and epigenetics with applications in cancer, stem cells, and immune responses. To identify and to understand the niche factors that govern stem cells fate, and drive them towards osteoblastic and/or chondrogenic lineages for tissue repair. To study ion channels in reproductive, airway and bone health and diseases, and in particular the development of ion channels into molecular targets for biomedical engineering approaches in the diagnosis/treatment of related human diseases. To develop microscale and nanoscale technologies with the ultimate goal of generating tissue-engineered organs and controlling cell behaviors for addressing clinical problems. To develop nanoparticle based theranostics (therapeutic diagnostics) capable of imaging, drug delivery and monitoring the therapeutic responses in single platform, enabling targeted cancer therapy and stem cell tracking.

 

Faculty members in this research area:
  • Dr Thomas Lee
  • Dr Youhua Tan
  • Dr Chunyi Wen
  • Prof Mo Yang
  • Dr. Sharon Y.C. RUAN
  • Dr. Xin ZHAO
 

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