AP Seminar - Drug Screening on Digital Microfluidics for Cancer Precision Medicine
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Date
19 Aug 2025
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Organiser
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Time
14:00 - 15:30
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Venue
BC301, 3/F, Wing BC, PolyU Map
Speaker
Prof. Yanwei Jia
Summary
Digital Microfluidics (DMF) is a cutting-edge technology for manipulating individual droplets on-chip based on the phenomenon of electro-wetting on dielectric (EWOD). The utilization of electrical signal for droplet control in DMF eliminates the bulky external pumps and valves in traditional channel-based microfluidics, making DMF an ideal system for disease diagnostics with limited amount of biopsy samples. In this talk, I will introduce our recent progress in the development of digital microfluidics for drug screening on DMF for cancer precision medicine, including 3D microstructures for single-cell drug screening, electro-jetting for wide ranged flexible drug dispensing, single and combinational drug screening on-chip, cancer diagnosis based on single-cell impedance sensing on integrated circuit (IC) chip, and drug screening of primary tumor cells on chip for precision medicine. All these investigations have paved the way for automatic digital microfluidic systems for precision medicine in the future.
Keynote Speaker
Prof. Yanwei Jia
Associate Professor
State Key Laboratory of Analog and Mixed-Signal VLSI, Institute of Microelectronics
University of Macau
Dr. Yanwei Jia received the Ph.D. degree in physics from National University of Singapore and the postdoctoral training in biology at Brandeis University in the US. She is currently an associate professor at the State Key Laboratory of Analog and Mixed-Signal of VLSI, Institute of Microelectronics at University of Macau. Her research interests lie in the multidisciplinary fields of digital microfluidics and its applications in biomedicine. She has authored or co-authored more than 60 referred journal papers and filed over 20 national and international patents. She is also a co-founder of a start-up company, ProMedicine Technology in China.
