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Dr S.W. Shan
Open Platform for University Scholars

Dr Samantha SHAN

Research Assistant Professor


Dr Samantha SW Shan obtained her Bachelor’s degree in Biochemistry from The Chinese University of Hong Kong (CUHK). After completing her undergraduate studies, she obtained her PhD degree in the Department of Anatomy in CUHK (which is now under the School of Biomedical Science). Following this, she spent about four years as a Postdoctoral Fellow in the Sunnybrook Health Science Centre, an affiliated hospital of University of Toronto, Canada, where she was involved in microRNA studies associated with hepatocellular carcinoma in microRNA-transgenic mice. Her work was very well received in conference presentations and resulted in a number of publications in high impact journals, including Nature Cell Biology, FASEB Journal and the Journal of Cell Science. Prior to joining The Hong Kong Polytechnic University, she has worked as a laboratory director in a private cord blood bank in Hong Kong for three years. Dr Shan joined School of Optometry as a Research Fellow in 2014 and is currently a Research Assistant Professor in the School.

Dr Shan has more than ten year’s local and overseas experience in molecular research. She is proficient in adopting both genomic and proteomic approaches in her work. Dr Shan’s research interest is the pathophysiology of glaucoma. Her research is attempting to unravel the mechanisms of aqueous humor secretion, outflow facility, and intraocular pressure (IOP). Her research associated with ocular health has been published in international journals including Investigative Ophthalmology and Vision Science, Scientific Reports, Journal of Proteomics, J. Proteome Research and Oxidative Medicine and Cellular Longevity.

Research Interests

  • Mechanism of aqueous humor formation, outflow facility and IOP regulation
  • MicroRNAs on outflow facility
  • DNA methylation of potential candidates on outflow facility and IOP regulation

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