Our microbiome laboratory introduces Hong Kong's first Simulator of Human Intestinal Microbial Ecosystem (SHIME). No similar instruments available in Hong Kong, SHIME is fully automated and controlled by computer. It allows direct comparison of different treatments (microbiota, placebo vs treatment, etc.) and could be designed specifically depending on the type of person (such as baby, adult or elderly). It is an ideal system to test harmful and infectious agents.
SHIME has its broad applications such as short-term screening for drugs, microbiome analyses, absorption and bioavailability, host response, strain characterization and pathogen-host interaction.