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Dr Chui Wa Christina Poon
PolyU Scholars Hub

Dr Poon Chui-wa, Christina

Research Assistant Professor

Education and Academic Qualifications

  • Bachelor of Science, The University of Leeds
  • Master of Philosophy, The Chinese University of Hong Kong
  • Doctor of Philosophy, The Chinese University of Hong Kong

Research Overview

The focus of my research area is to study the use and underlying mechanisms of Chinese herbal medicine and the active ingredients for improving musculoskeletal health and the management of aging-related diseases.

Research Interests

  • Chinese herbal medicine
  • Osteoporosis
  • Sarcopenia
  • Bone and mineral metabolism
  • Aging-related diseases

Achievements

  1. Li WX, Qin XH, Poon CCW, Wong MS, Feng R, Wang J, Lin FH, Sun YL, Liu SF, Wang YJ and Zhang Y (2021). Vitamin D/Vitamin D Receptor Signaling Attenuates Skeletal Muscle Atrophy by Suppressing Renin-Angiotensin System. Journal of Bone and Mineral Research. doi: 10.1002/jbmr.4441.
  2. Zhou L, Poon CCW*, Wong KY, Cao S, Dong X, Zhang Y and Wong MS (2021). Icariin ameliorates estrogen-deficiency induced bone loss by enhancing IGF-I signaling via its crosstalk with non-genomic ERα signaling. Phytomedicine. 82:153413. doi: 10.1016/j.phymed.2020.153413.
  3. Zhou L, Poon CCW*, Wong KY, Cao S, Yu W, Dong X, Lee WY, Zhang Y and Wong MS (2019). Prenylflavonoid Icariin Induces Estrogen Response Element-Independent Estrogenic Responses in a Tissue-Selective Manner. Journal of the Endocrine Society. 4(2):bvz025. doi: 10.1210/jendso/bvz025.
  4. Wong MS, Poon CCW, Zhou LP and Xiao HH (2019). Natural Products as Potential Bone Therapies. Handbook of experimental pharmacology. doi: 10.1007/164_2019_322.
  5. Ho MX, Poon CCW*, Wong KC, Qiu ZC and Wong MS (2018). Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERα Signaling. Frontiers in Pharmacology. 9:474. doi: 10.3389/fphar.2018.00474.
  6. Poon CCW, Li RWS, Seto SW, Kong SK, Ho HP, Hoi MP, Lee SMY, Ngai SM, Chan SW, Leung GPH and Kwan YW (2015). In vitro vitamin K2 and 1α,25-dihydroxyvitamin D3 combination enhances osteoblasts anabolism of diabetic mice. European Journal of Pharmacology. 2015; 767: 30-40. doi: 10.1016/j.ejphar.2015.09.048.
  7. Poon CCW, Seto SW, Au ALS, Zhang Q, Li RWS, Lee WYW, Leung GPH, Kong SK, Yeung JHK, Ngai SM, Ho HP, Lee SMY, Chan SW and Kwan YW (2010). Mitochondrial monoamine oxidase A-mediated hydrogen peroxide generation enhances 5-hydroxytryptamine-induced contraction of rat basilar artery. British Journal of Pharmacology. 161:1086-1098. doi: 10.1111/j.1476-5381.2010.00941.x.

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