Dr Ng Cheuk-chi

Academic Staff

Research Assistant Professor

Y824-05
+852 3400 2609
cheuk-chi.a.ng@polyu.edu.hk

Research Overview

Our research interests lie in mass spectrometry, proteomics, chemical biology, and information technology, and the integration of these areas for interdisciplinary research, such as data storage using peptides and proteins and developing a peptide library for protein binding and drug development.

Research Interests

Achievements

Yao, Z. P.; Zhou, Y.; Ng, C. C.; Liu, C. X. Data storage using proteins. PCT application No. PCT/CN2023/108347 (filed 20/07/2023)
Yao, Z.; Ng, C. C. A.; Lau, C. M.; Tam, W. M. Sequencing data-encoded peptides from tandem mass spectra. EU patent No. EP 4261826 (granted 05/03/2025); US non-provisional patent application No. 18/297,685 (filed 10/04/2023); CN patent application No.: P24143CN00 (filed 10/04/2023)
Yao, Z. P.; Ng, C. C. A.; Lau, F. C. M.; Tam, W. M. Data storage using peptides. US patent No. 11,315,023 (granted 26/04/2022); EU patent No. EP 3776557 (granted 29/01/2025); CN patent No. ZL 201880094641.4 (granted 07/02/2025)
Yao, Z. P.; Ng, C. C. A.; Yin, H. D. Data storage using peptides. US continuation-in-part patent No. 11,302,421 B2 (granted 12/04/2022)
Yao, Z. P.; Ng, C. C. A.; Ng, T. T.; Li, S. Edible oil analysis system and method. US patent No. 10,859,552 (granted 08/12/2020)

Luo, X., Ng, C. C. A., Lam, H. H. N., Yao, Z.-P. Advances in protein sequencing: Techniques, challenges and prospects. Trends Anal. Chem., 2025, under review
Ng, C. C. A., Zhou, Y., Yao, Z.-P. Algorithms for de-novo sequencing of peptides by tandem mass spectrometry: A review. Anal. Chim. Acta, 2023, 1268, 341330
Ng, C. C. A., Tam, W. M., Yin, H., Wu, Q., So, P.-K., Wong. M. Y. M., Lau, F. C. M., Yao, Z.-P. Data storage using peptide sequences. Nat. Commun., 2021, 12, 4242
Ng, T. T.; Li, S. Y.; Ng, C. C. A.; So, P. K.; Wong, T. F.; Li, Z. Y.; Chan, S. T.; Yao, Z.-P. Establishment of a spectral database for classification of edible oil. Food Chem., 2018, 252, 335–342
Kundu, M.; Ng, C. C. A.; Petrovykh, D. Y.; Liu, L. Nickel foam supported mesoporous MnO2 nanosheet arrays with superior lithium storage performance. Chem. Commun., 2013, 49, 8459-8461
Ng, C. C. A.; Magenau, A.; Ngalim, S. H.; Ciampi, S.; Chockalingham, M.; Harper, J. B.; Gaus, K.; Gooding, J. J. Using an electrical potential to reversibly switch surfaces between two states for dynamically controlling cell adhesion. Angew. Chem., 2012, 124, 7826–7830
James, M.; Darwish, T. A.; Ciampi, S.; Sylvester, S. O.; Zhang, Z.; Ng, A.; Gooding, J. J.; Hanley, T. L. Nanoscale condensation of water on self-assembled monolayers. Soft Matter, 2011, 7, 5309-5318
Ng, C. C. A.; Le Saux, G.; Chockalingam, M.;Ciampi, S.; Harper, J. B.; Gooding, J. J. Preparation of thiol-terminated monolayers on silicon(100) surfaces using thioacetyl-protected alkynethiol. 2010 International Conference on Nanoscience and Nanotechnology (ICONN), 2010, 244-247
Ng, C. C. A.; Ciampi, S.; Harper, J. B.; Gooding, J. J. Antifouling behaviour of silicon surfaces modified with self-assembled monolayers containing both ethylene glycol and charged moieties. Surf. Sci., 2010, 604, 1388-1394
Ng, A.; Ciampi, S.; James, M.; Harper, J. B.; Gooding, J. J. Comparing the reactivity of alkynes and alkenes on silicon (100). Langmuir, 2009, 25, 13934-13941