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Dr Jingyu SHI

Dr Jingyu SHI

Research Assistant Professor

Biography

Dr SHI Jingyu is currently a Research Assistant Professor (RAP) in the Department of Biomedical Engineering (BME) at The Hong Kong Polytechnic University (PolyU). She received her B.Eng degree in Polymer Materials and Engineering from Sichuan University (SCU) in 2012. She received her M.Phil. and Ph.D. degrees in Biomedical Engineering from The Hong Kong Polytechnic University in 2015 and 2018, respectively. From 2021 to 2023, she served as a postdoctoral fellow at the Hong Kong Polytechnic University under the RGC Postdoctoral Fellowship Scheme (PDFS) 2022/23. Dr Shi's research focuses on developing novel nanomaterial-based nanoprobes and advanced biosensing technologies to achieve highly sensitive and specific detection of biomarkers in complex samples and cells. She is also working on the development of theranostic nanobiocomposites that enable bioimaging-guided precision therapy. In her current research, she is interested in exploring the potential of combinations of nanomaterials and exosomes in immunotherapy. She has published more than 16 papers (including one ESI highly cited paper) in SCI journals, such as ACS Nano, Biosensors & Bioelectronics, ACS Applied Materials & Interfaces, Sensors and Actuators B-Chemical, Journal of Materials Chemistry B, Droplet, Biomicrofluidics, etc.

Education and Academic Qualifications

  • Ph.D. in Biomedical Engineering, The Hong Kong Polytechnic University
  • M.Phil. in Biomedical Engineering, The Hong Kong Polytechnic University
  • B.Eng. in Polymer Materials and Engineering, Sichuan University

Academic and Professional Experience

  • Research Assistant Professor, Department of Biomedical Engineering, The Hong Kong Polytechnic University, 01/2024 – Current
  • Postdoctoral Fellow, Department of Biomedical Engineering, The Hong Kong Polytechnic University, 2021 – 2023

Research Interests

  • Nanomaterials
  • Exosomes
  • Biosensing
  • Theranostics

Research Output

  1. J.Y. Shi, Y. Zhang, Y.D. Fan, Y. Liu, M. Yang, Recent advances in droplet-based microfluidics in liquid biopsy for cancer diagnosis, Droplet, 2024, e92.
  2. J.Y. Shi, Y. Zhang, M. Yang*, Recent development of microfluidics-based platforms for respiratory virus detection, Biomicrofluidics, 2023, 17(2), 024104.
  3. M.T. Au#, J.Y. Shi#, Y.D. Fan, J.G. Ni, C.Y. Wen, M. Yang, Nerve growth factor-targeted molecular theranostics based on molybdenum disulfide nanosheet coated gold nanorods (MoS2-AuNR) for osteoarthritis pain, ACS Nano, 2021, 15, 7, 11711–11723. (#Co-first author)
  4. J.Y Shi, J. Lyu, F. Tian, M. Yang*, A fluorescence turn-on biosensor based on graphene quantum dots (GQDs) and molybdenum disulfide (MoS2) nanosheets for epithelial cell adhesion molecule (EpCAM) detection, Biosensors & Bioelectronics, 2017, 93, 182–188.
  5. J.Y. Shi, F. Tian, J. Lyu, M. Yang, Nanoparticle based fluorescence resonance energy transfer (FRET) for biosensing applications, Journal of Materials Chemistry B, 2015, 3, 6989-7005. (Mostly downloaded paper)
  6. J.Y. Shi, C.Y. Chan, Y.T. Pang, W.W. Ye, F. Tian, J. Lyu, Y. Zhang, M. Yang, A fluorescence resonance energy transfer (FRET) biosensor based on graphene quantum dots (GQDs) and gold nanoparticles (AuNPs) for the detection of mecA gene sequence of Staphylococcus aureus, Biosensors & Bioelectronics, 2015, 67, 595–600. (“Highly Cited Paper” in Essential Science Indicators (ESI)) (top 1% of the academic field of Chemistry)
  7. J.Y. Shi, J.B. Guo, G.X. Bai, C.Y. Chan, X. Liu, W.W. Ye, J.H. Hao, S. Chen, M. Yang*, A Graphene Oxide based Fluorescence Resonance Energy Transfer (FRET) Biosensor for Ultrasensitive Detection of Botulinum Neurotoxin A (BoNT/A) Enzymatic Activity, Biosensors & Bioelectronics, 2015, 65 238-244.
  8. C.Y. Chan, J.Y. Shi, Y.D. Fan, M. Yang, A microfluidic flow-through chip integrated with reduced graphene oxide transistor for influenza virus gene detection, Sensors and Actuators B- Chemical, 2017, 251, 927-933.
  9. W.W. Ye, J.Y. Shi, C.Y. Chan, Y. Zhang, M. Yang, A nanoporous membrane based impedance sensing platform for DNA sensing with gold nanoparticle amplification, Sensors and Actuators B-Chemical, 2014, 193, 877-882.

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