The University Research Facility in Life Sciences (ULS) is organising a Distinguished Lecture on Super-resolution Fluorescence Microscopy by Prof. LI Dong, xinghua chair professor, new cornerstone investigator at school of life science, Tsinghua University.
Prof. Li pioneered the development of advanced imaging systems, including high numerical aperture total internal reflection structured illumination microscopy (TIRF SIM, Science 2015 grazing incidence SIM (GI SIM, Cell 2018), 3D-SIM, nonlinear SIM, high speed lattice light sheet microscopy, and 3D high spatiotemporal resolution biomechanics microscopy. Complementing these hardware innovations, Prof. Li’s group also developed cutting edge algorithmic tools, such as the deep Fourier channel attention network (Nat Methods 2021, 2025) and the rationalized deep learning (rDL) architecture (Nat Biotech 2023, 2025). These advances enable the investigation of fragile and rapidly evolving subcellular bioprocesses with ultrahigh spatiotemporal resolution, facilitating unprecedented long term, multi colour imaging.
In this lecture, Prof. Li will report their latest advances of how to synergize the developments in both optical front end and algorithmic back-end methodology to address these challenges and apply them to a wide variety of fragile and rapid evolving subcellular bioprocesses at ultra-high spatiotemporal resolution for unprecedented long time, multi-colour imaging. Details of the Distinguished Lecture are as follows:
Date: 21 October, 2025 (Tuesday)
Time: 3:00 pm to 4:15 pm
Venue: Y716, Lee Shau Kee Building (Y Core), PolyU
Lecture title: Pushing the envelope of super-resolution microscopy for sustained live imaging of rapid subcellular processes
Online registration: https://forms.office.com/r/kqRDhLV3NJ
Should you have any enquiries, please contact Dr. Shuqi Zhang (Tel.: 3400 8923, shuqi.zhang@polyu.edu.hk) or Dr. Idy Ho (Tel.: 34008985, idyht.ho@polyu.edu.hk).
