Stigmatization is associated with many negative health behaviors and outcomes. Stigma itself is a multilevel, group-based phenomenon and is most amenable to a correspondingly multimodal research perspective. A key deficit of stigma research is the lack of a coherent model of culture. As well, much of the research that does incorporate culture is based on Asian immigrant populations in Western cultures. By contrast, research on the cultural, psychological, and communicative underpinnings of health stigma in Asia is severely lacking. In this seminar, I will address evidence recently collected in two ongoing research projects based in Hong Kong and Australia and in Hong Kong, Australia, and the Philippines, respectively. Quantitative arms with 1031 and 1413 participants, respectively, followed up by interviews with approximately 90 informants across the studies provide rich sources of data. This presentation will focus on differences across cultures in perceptions of stigmatized health conditions and will particularly examine the role of the construct of moralization in these processes. As well, time permitting, I will cover some of the cultural differences we found in willingness to communicate stigmatization.