ORCID ID
SCOPUS ID研究概述
Our research encompasses both basic and applied studies focused on the design and development of innovative therapeutics and diagnostic tools, integrating chemical, biological, and computational approaches.
學歷
- Bachelor of Science in Medicinal Chemistry, China Pharmaceutical University
- Master of Science in Molecular Chemistry, École polytechnique
- Doctor of Philosophy in Chemistry, École polytechnique
- Massachusetts Institute of Technology
專業資格
- Licensed Pharmacist (China)
- Registered Pharmacist (Australia)
Academic and Professional Experience
- Standing Committee Member, Pharmaceutical Engineering Committee of Guangdong Pharmaceutical Association (2024 - Present)
- Assessment Panel Member, Hong Kong Science & Technology Park (2024 - Present)
- Member, Chinese Chemical Society (2019 - Present)
- Member, American Chemical Society (2016 - Present)
- Member, American Society of Microbiology (2016 - Present)
- Director, Marshall Research Centre for Medical Microbial Biotechnology, PolyU (2025 - Present)
- Faculty Award For Outstanding Achievement for Impact to Industry, PolyU (2024)
- Departmental Excellence Award (Research Impact), PolyU (2023)
- Winner of Science Breakthrough of the Year in the Category of Science Start-ups, Falling Walls Foundation, Germany (2023)
- Global Innovation Award, TechConnect World Innovation Conference & Expo, USA (2019)
- Honorary Visiting Fellowship, University of Technology Sydney, Australia (2019)
- Faculty Early Career Research Award, University of Newcastle, Australia (2015)
- Ma C. Nickel Catalyzed Beta-Arylation/Benzylation of 2'-Hydroxy-Chalcone. US Patent App No. 63/738,847
- Ma C, Chan PK-s, Yang X, Chan WY, Ye J. N-Substituted oseltamivir derivatives with antimicrobial activity. US Patent 12378208
- Ma C. In vitro detection method of protein-protein interactions, assay kit, and applications. CN Patent ZL201811388110.4
- Ko BCB, Ma C, Zhang Y, Chen Y, Zhang Y. CTCF transcription factor inhibitors and applications. CN Patent ZL201910562893.1
- Ma C. Compounds with Antimicrobial Activity. U.S. Patent App No. 17/250,178
- Ma C, Yang X. Compounds with Antimicrobial Activity. CN Patent ZL201980007063.0; US Patent 11479529; EP Patent 3737664; JP Patent 7450887
- Liu, T.; Kan, C. H.; Zheng, Y.; Tsang, T. F.; Liu, Y.; Tsang, M. W.; Fang, H.; Lam, L. Y.; Yang, X.; Ma, C. Development of triaryl antimicrobials by scaffold hopping from an aminopropanol hit targeting bacterial RNA polymerase-NusG interactions. Journal of Enzyme Inhibition and Medicinal Chemistry 2025, 40, 2543923. DOI: 10.1080/14756366.2025.2543923
- Lam, L. Y.; Ma, C. Transition-Metal Free Photocatalytic Synthesis of Acylsulfonamides. Organic Letters 2025, 27, 4732–4736. DOI: 10.1021/acs.orglett.5c01129
- Zheng, Y.; Kan, C. H.; Tsang, T. F.; Liu, Y.; Liu, T.; Tsang, M. W.; Lam, L. Y.; Yang, X.; Ma, C. Discovery of Inhibitors Targeting Protein–Protein Interaction between Bacterial RNA Polymerase and NusG as Novel Antimicrobials. Journal of Medicinal Chemistry 2024, 67, 16556–16575. DOI: 10.1021/acs.jmedchem.4c01386
- Xu, P.; Ma, C. Scalable deoxygenative alkynylation of alcohols via flow photochemistry. Communications Chemistry 2024, 7, 276. DOI: 10.1038/s42004-024-01363-4
- Lam, L. Y.; Chan, K. H.; Ma, C. Copper-Catalyzed Synthesis of Functionalized Aryl Sulfonamides from Sodium Sulfinates in Green Solvents. The Journal of Organic Chemistry 2022, 87, 8802–8810. DOI: 10.1021/acs.joc.2c00777
- Lam, L. Y.; Ma, C. Chan–Lam-Type C–S Coupling Reaction by Sodium Aryl Sulfinates and Organoboron Compounds. Organic Letters 2021, 23, 6164–6168. DOI: 10.1021/acs.orglett.1c02299
- Ye, J.; Chu, A. J.; Harper, R.; Chan, S. T.; Shek, T. L.; Zhang, Y.; Ip, M.; Sambir, M.; Artsimovitch, I.; Zuo, Z.; Yang, X.; Ma, C. Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors. Journal of Medicinal Chemistry 2020, 63, 7695–7720. DOI: 10.1021/acs.jmedchem.0c00520
- Liu, Y.; Lam, L. Y.; Ye, J.; Blanchard, N.; Ma, C. DABCO-promoted Diaryl Thioether Formation by Metal-catalyzed Coupling of Sodium Sulfinates and Aryl Iodides. Advanced Synthesis & Catalysis 2020, 362, 2326–2331. DOI: https://doi.org/10.1002/adsc.202000221
- Qiu, Y.; Chan, S. T.; Lin, L.; Shek, T. L.; Tsang, T. F.; Barua, N.; Zhang, Y.; Ip, M.; Chan, P. K.-s.; Blanchard, N.; Hanquet, G.; Zuo, Z.; Yang, X.; Ma, C. Design, synthesis and biological evaluation of antimicrobial diarylimine and –amine compounds targeting the interaction between the bacterial NusB and NusE proteins. European Journal of Medicinal Chemistry 2019, 178, 214–231. DOI: https://doi.org/10.1016/j.ejmech.2019.05.090.
- Yang, X.; Ming Jing, L.; Yeung, A.; Lewis, P.; Chan, P.; Ip, M.; Ma, C. First-In-Class Inhibitor of Ribosomal RNA Synthesis with Antimicrobial Activity against Staphylococcus Aureus. Biochemistry 2017, 56. DOI: 10.1021/acs.biochem.7b00349
