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Mr. Chunghim SO | Mr. Dong LIANG | Mr. Milan RAI | Ms. Jing ZHANG | Ms. Shuwen JIA | Ms. Wing Yan LAU | Ms. Yingkun CUI | Ms Jingfang Jennifer BIAN | Mr Shashi Kant CHAUDHARY | Ms Meng CHENG | Mr Ka Wai Jimmy CHEUNG | Mr Kai Yip CHOI | Ms Hang I Christie LAM | Ms Hoi Lam LI | Ms Sonal Aswin VYAS | Mr Kin Ken WAN | Ms Biyue GUO | Ms Li PAN | Ms Qi TAN | Mr Mezbah UDDIN | Mr Bing Yuan KONG | Ms Rong LI | Ms. Yuanyuan LIANG | Ms Anqi LYU | Mr Ying Hon SZE | Ms Qin WANG | Ms Hanyu ZHANG | Ms Wei YANG | Ms Mei ZHAO | Ms Yajing YANG | Ms Fangyu XU | Mr Sung Hei Jimmy TSE | Ms. Seen Hang CHAN

Ms Jingfang Jennifer BIAN

Ms Jingfang Jennifer BIAN
PhD Student (Part-time)

ORCiD 0000-0003-0464-1705
Author ID (Scopus) 57201059638

Title of project:
Proteomics in Lens Induced Myopic (LIM) Mammalian Model

A complete picture of molecular events involving myopic development remains obscure. Previous studies support the hypothesis that biochemical cascades in myopic eye growth flow from the retina to the sclera. However, most of the previous studies focused mainly on the single target approach which generated limited biochemical information on the interaction among multiple candidates. Mass spectrometric (MS)-based proteomics approach has been proven to be a powerful approach to study global protein expressions in complex biological samples. Some differential protein expressions have also been reported in previous proteomic work using avian myopia model.

This project aims to identify and quantify retinal protein expressions during early emmetropisation and myopia development using guinea pig model based on the next generation proteomics approach combining with sophisticated bioinformatics. The data generated from this mammalian myopia model will be more relevant to understand the complicated biochemical pathways in human myopia.