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About us > Our Research > Publications > Representative Publications on Myopia > 2009-2013
Our Research
Representative Publications on Myopia | Representative Publications on the Ageing Eye | Other Publications


Title Authors
Corneal shapes of Chinese emmetropes and myopic astigmats aged 10 to 45 years. Optometry and Vision Science 2013;90(11):1259-1266 Leung TW, Lam AKC, Kee CS
Prevalence of myopia-related retinal changes among 12-18 year old Hong Kong Chinese high myopes. Ophthalmic Physiol Opt 2013;33:652-60.
Cheng SC, Lam CS, Yap MK
Myopia control using toric orthokeratology (To-See Study). Invest Ophthalmol Vis Sci 2013;54:6510-7.
Chen C, Cheung SW, Cho P
Cytotoxicity of rigid gas-permeable lens care solutions. Clin Exp Optom 2013;96:467-71.
Choy CK, Cho P, Boost MV
Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error. American Journal of Human Genetics 2013;93,264-277.
Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJM, Barathi VA, Liao J, Hysi PG, Bailey-Wilson JE, St. Pourcain B, Kemp JP, McMahon G, Timpson, NJ, Evans DM, Montgomery GW, Mishra A, Wang YX, Wang JJ, Rochtchina E, Polasek O, Wright AF, Amin N, Van Leeuwen EM., Wilson JF, Pennell CE, Van Duijn CM., De Jong PTVM, Vingerling JR., Zhou X, Chen P, Li R, Tay WT, Zheng Y, Chew M, Burdon KP, Craig JE, Iyengar SK, Igo RP, Lass JH, Chew EY, Haller T, Mihailov E, Metspalu A, Wedenoja J, Simpson CL, Wojciechowski R, Höhn R, Mirshahi A, Zeller T, Pfeiffer N, Lackner KJ, Bettecken T, Meitinger T, Oexle K, Pirastu M, Portas L, Nag A, Williams KM, Yonova-Doing E, Klein R, Klein BE, Hosseini SM, Paterson AD, Makela KM, Lehtimaki T, Kahonen M, Raitakari O, Yoshimura N, Matsuda F, Chen LJ, Pang CP, Yip SP, Yap MKH, Meguro A, Mizuki N, Inoko H, Foster PJ, Zhao JH, Vithana E., Tai ES, Fan Q, Xu, L, Campbell H, Fleck B, Rudan I, Aung T, Hofman A, Uitterlinden AG, Bencic G, Khor CC, Forward H, Pärssinen O, Mitchell P, Rivadeneira F, Hewitt AW, Williams C, Oostra BA, Teo YY, Hammond CJ, Stambolian D, Mackey DA, Klaver CCW, Wong TY, Saw SM and Baird PN
High myopia-partial reduction orthokeratology (HM-PRO): Study design. Cont Lens Anterior Eye 2013;36:164-70.
Charm J, Cho P
A novel missense mutation in the NYX gene associated with high myopia. Ophthalmic Physiol Opt 2013;33:346-53.
Yip SP, Li CC, Yiu WC, Hung WH, Lam WW, Lai MC, Ng PW, Fung WY, Chu PH, Jiang B, Chan HH, Yap MK
Astigmatism and its role in emmetropization. Exp Eye Res 2013;1-7.
Kee CS
High Myopia-Partial Reduction Ortho-k: A 2-Year Randomized Study. Optom Vis Sci 2013;90:530-9.
Charm J, Cho P
On the shoulders of a giant: his legacy will live on. Ophthalmic Physiol Opt 2013;33:193-5.
Wildsoet CF, Nickla DL, Guggenheim JA, Logan NS
An introduction to point-counterpoint articles. Ophthalmic Physiol Opt 2013;33:354. Wildsoet C, Nickla DL, Guggenheim J, Logan NS
Disruption of the centrifugal visual system inhibits early eye growth in chicks. Invest Ophthalmol Vis Sci 2013;54:3632-43.
Dillingham CM, Guggenheim JA, Erichsen JT
Coordinated genetic scaling of the human eye: shared determination of axial eye length and corneal curvature. Invest Ophthalmol Vis Sci 2013;54:1715-21.
Guggenheim JA, Zhou X, Evans DM, Timpson NJ, McMahon G, Kemp JP, St Pourcain B, Northstone K, Ring SM, Fan Q, Wong TY, Cheng CY, Khor CC, Aung T, Saw SM, Williams C
Association mapping of the high-grade myopia MYP3 locus reveals novel candidates UHRF1BP1L, PTPRR, and PPFIA2. Invest Ophthalmol Vis Sci 2013;54:2076-86.
Hawthorne F, Feng S, Metlapally R, Li YJ, Tran-Viet KN, Guggenheim JA, Malecaze F, Calvas P, Rosenberg T, Mackey DA, Venturini C, Hysi PG, Hammond CJ, Young TL
Improving Interobserver Variation in Corneal Sublayer Pachymetry Using ConfoScan4 With Z Ring. Eye Contact Lens 2013;39:214-9.
Wong YZ, Lam AK
Relative peripheral refraction in children: twelve-month changes in eyes with different ametropias. Ophthalmic Physiol Opt 2013;33:283-93.
Lee TT, Cho P
Prevalence of papillary changes and folliculosis of the palpebral conjunctiva in asymptomatic Chinese children. Cont Lens Anterior Eye 2013;36:62-5.
Chan KY, Cho P, Chan YY, Cheung SW, Swann PG
Validity of axial length measurements for monitoring myopic progression in orthokeratology. Invest Ophthalmol Vis Sci 2013;54:1613-5.
Cheung SW, Cho P
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet 2013;45:314-318.
Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Hohn R, Macgregor S, Hewitt AW, Nag A, Cheng CY, Yonova-Doing E, Zhou X, Ikram MK, Buitendijk GH, McMahon G, Kemp JP, ST Pourcain B, Simpson CL, Makela KM, Lehtimaki T, Kahonen M, Paterson AD, Hosseini SM, Wong HS, Xu L, Jonas JB, Parssinen O, Wedenoja J, Yip SP, Ho DW, Pang CP, Chen LJ, Burdon KP, Craig JE, Klein BEK, Klein R, Haller T, Metspalu A, Khor CC, Tai ES, Aung T, Vithana E, Tay WT, Barathi VA, Consortium for Refractive Error and Myopia (CREAM), Chen P, Li R, Liao J, Zheng Y, Ong RT, Doring A, The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Research Group, Evans DM, Timpson NJ, Verkerk AJMH, Meitinger T, Raitakari O, Hawthorne F, Spector TD, Karssen LC, Pirastu M, Murgia F, Ang W, Wellcome Trust Case Control Consortium 2 (WTCCC2), Mishra A, Montgomery GW, Pennell CE, Cumberland PM, Cotlarciuc I, Mitchell P, Wang JJ, Schache M, Janmahasathian S, Igo JR RP, Lass JH, Chew E, Iyengar SK, The Fuchs' Genetics Multi-Center Study Group, Gorgels TG, Rudan I, Hayward C, Wright AF, Polasek O, Vatavuk Z, Wilson JF, Fleck B, Zeller T, Mirshahi A, Muller C, Uitterlinden AG, Rivadeneira F, Vingerling JR, Hofman A, Oostra BA, Amin N, Bergen AA, Teo YY, Rahi JS, Vitart V, Williams C, Baird PN, Wong TY, Oexle K, Pfeiffer N, Mackey DA, Young TL, van Duijn CM, Saw SM, Bailey-Wilson JE, Stambolian D, Klaver CC, Hammond CJ
Daily disposable lenses: The better alternative. Cont Lens Anterior Eye 2013;36:4-12.
Cho P, Boost MV
Full correction and undercorrection of myopia evaluation trial: design and baseline data of a randomized, controlled, double-blind trial. Clin Exp Ophthalmol 2013;41(4):329-338. Li SM, Li SY, Liu LR, Guo JY, Chen W, Wang NL, Millodot M.
Clinical evaluation of the L80 autorefractometer. Clin Exp Optom 2012;95(1):66-71. Shneor E, Millodot M, Avraham O, Amar S, Gordon-Shaag A.
Investigating the relationship between UMODL1 gene polymorphisms and high myopia: a case-control study in Chinese. BMC Med Genet 2012;13:64. Zhu MM, Yap M, Ho DW, Fung WY, Ng PW, Gu YS, Yip SP
Repeatability of relative peripheral refraction in untreated and orthokeratology-treated eyes. Optom Vis Sci 2012;89:1477-86. Lee TT, Cho P
Retardation of Myopia in Orthokeratology (ROMIO) Study: A 2-Year Randomized Clinical Trial. Invest Ophthalmol Vis Sci 2012;53:7077-85. Cho P, Cheung SW
Global flash multifocal electroretinogram: early detection of local functional changes and its correlations with optical coherence tomography and visual field tests in diabetic eyes. Doc Ophthalmol 2012;125:123-35. Lung JC, Swann PG, Wong DS, Chan HHL
Comparison of contamination rates of designs of rigid contact lens cases. Optom Vis Sci 2012;89:E1030-4. Boost MV, Shi G, Cho P
Myopia progression in children is linked with reduced foveal mfERG response. Invest Ophthalmol Vis Sci 2012:5320-25. Ho WC, Kee CS, Chan HH
Clinical performance of an orthokeratology lens fitted with the aid of a computer software in Chinese children. Cont Lens Anterior Eye 2012;35:180-4.  Chan KY, Cheung SW, Cho P 
Repeatability of corneal biomechanical measurements in children wearing spectacles and orthokeratology lenses. Ophthalmic Physiol Opt 2012;32:349-54.  Hon Y, Cheung SW, Cho P, Lam AK 
Characteristics of astigmatism as a function of age in a Hong Kong clinical population. Optom Vis Sci 2012;89:984-92.  Leung TW, Lam AK, Deng L, Kee CS 
Temporal interactive response is resistant to cloudy ocular media in the slow double-stimulation multifocal electroretinogram. Br J Ophthalmol 2012;96:1012-7.  Ho WC, Chu PH, Ng YF, Tong PP, Woo VC, Chan HH  
Association of High Myopia with Crystallin Beta A4 (CRYBA4) Gene Polymorphisms in the Linkage-Identified MYP6 Locus. PLoS One 2012;7:e40238. Ho DW, Yap MK, Ng PW, Fung WY, Yip SP
Myopic Children Have Central Reduction in High Contrast Multifocal ERG Response, While Adults Have Paracentral Reduction in Low Contrast Response. Invest Ophthalmol Vis Sci 2012;53:3695-702.   Ho WC, Kee CS, Chan HH  
Toric orthokeratology for highly astigmatic children. Optom Vis Sci 2012;89:849-55.   Chen CC, Cheung SW, Cho P 
Do fenestrations affect the performance of orthokeratology lenses? Optom Vis Sci 2012;89:401-10. Cho P, Chan B, Cheung SW, Mountford J  
Nidek ConfoScan 4 (z-ring) measurements over soft contact lenses. Eye Contact Lens 2012;38:80-5.  Chan KY, Cheung SW, Cho P
Association of IGF1 gene haplotypes with high myopia in Chinese adults. Arch Ophthalmol 2012;130:209-16. Mak JY, Yap MK, Fung WY, Ng PW, Yip SP  
UPDG: Utilities package for data analysis of Pooled DNA GWAS. BMC Genet 2012;13:1.  Ho DW, Yap M, Yip SP 
Cytotoxicity and effects on metabolism of contact lens care solutions on human corneal epithelium cells. Clin Exp Optom 2012;95:198-206.  Choy CK, Cho P, Boost MV 
Corneal parameters of six- to 12-year-old Chinese children. Clin Exp Optom 2012;95:160-5.  Chan KY, Cheung SW, Cho P 
Effects of hemiretinal form deprivation on central refractive development and posterior eye shape in chicks. Vision Res 2012;55:24-31.  Chu CH, Deng L, Kee CS
Prevalence of myopia among Hong Kong Chinese schoolchildren: changes over two decades. Ophthalmic Physiol Opt 2012;32:17-24.  Lam CS, Lam CH, Cheng SC, Chan LY 
Amoebicidal effects of contact lens disinfecting solutions. Optom Vis Sci 2012;89:44-51.  Boost MV, Shi GS, Lai S, Cho P 
Visual outcome of Soflens Daily Disposable and Soflens Daily Disposable for Astigmatism in subjects with low astigmatism. Clin Exp Optom 2012;95:43-7.  Cho P, Cheung SW, Charm J 
Toric orthokeratology for high myopic and astigmatic subjects for myopic control. Clin Exp Optom 2012;95:103-8.  Chen C, Cho P
Sign-dependent changes in retinal electrical activity with positive and negative defocus in the human eye. Vision Res 2012;52:47-53.  Ho WC, Wong OY, Chan YC, Wong SW, Kee CS, Chan HH
Interocular symmetry in myopic anisometropia. Optom Vis Sci 2011;88:1454-62. Vincent SJ, Collins MJ, Read SA, Carney LG, Yap MK
Genotyping performance assessment of whole genome amplified DNA with respect to multiplexing level of assay and its period of storage. PLoS ONE 2011;6:e26119.  Ho DWH, Yiu WC, Yap MKH, Fung WY, Ng PW, Yip SP 
Characterisation of Cl transporter and channels in experimentally induced myopic chick eyes. Clin Exp Optom 2011;94:528-35.  Zhang H, Wong CL, Shan SW, Li KK, Cheng AK, Lee KL, Ge J, To CH, Do CW 
The effect of hydrogel and silicone hydrogel contact lenses on the measurement of intraocular pressure with rebound tonometry. Cont Lens Anterior Eye 2011;34:260-5.  Zeri F, Calcatelli P, Donini B, Lupelli L, Zarrilli L, Swann PG 
Influence of corneal astigmatism, corneal curvature and meridional differences on corneal hysteresis and corneal resistance factor. Clin Exp Optom 2011;94:418-24.  Wong YZ, Lam AKC 
Graded competing regional myopic and hyperopic defocus produce summated emmetropization set points in chick. Invest Ophthalmol Vis Sci 2011;52:8056-62. Tse DY, To CH
Corneal sublayer thickness measurements with the Nidek ConfoScan 4 (z Ring). Optom Vis Sci 2011;88:E1240-4. Chan KY, Cheung SW, Lam AK, Cho P
Contamination risk of reusing daily disposable contact lenses. Optom Vis Sci 2011;88:1409-13. Boost M, Poon KC, Cho P
Evaluation of proteoglycan gene polymorphisms as risk factors in the genetic susceptibility to high myopia. Invest Ophthalmol Vis Sci 2011;52:6396-403.   Yip SP, Leung KH, Ng PW, Fung WY, Sham PC, Yap MK 
Prevalence of diabetic retinopathy in patients with recently diagnosed diabetes mellitus. Clin Exp Optom 2011;94:371-5.   Lee KM, Sum WM  
Adherence of acanthamoeba to lens cases and effects of drying on survival. Optom Vis Sci 2011;88:703-7.  Boost M, Shi GS, Cho P 
A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population. Mol Vis 2011;17:810-21.  Yip SP, Leung KH, Fung WY, Ng PW, Sham PC, Yap MK 
A novel instrument for logging nearwork distance. Ophthalmic Physiol Opt 2011;31:137-44.  Leung TW, Flitcroft DI, Wallman J, Lee TH, Zheng Y, Lam CS, Kee CS 
Systematic Investigation of the Relationship between High Myopia and Polymorphisms of the MMP2, TIMP2, and TIMP3 Genes by a DNA Pooling Approach. Invest Ophthalmol Vis Sci 2011;52:3893-900.  Leung KH, Yiu WC, Yap MK, Ng PW, Fung WY, Sham PC, Yip SP 
Heritability of ocular component dimensions in chickens: genetic variants controlling susceptibility to experimentally induced myopia and pretreatment eye size are distinct. Invest Ophthalmol Vis Sci 2011;52:4012-20.  Chen YP, Prashar A, Erichsen JT, To CH, Hocking PM, Guggenheim JA 
Selective breeding for susceptibility to myopia reveals a gene-environment interaction. Invest Ophthalmol Vis Sci 2011;52:4003-11.  Chen YP, Hocking PM, Wang L, Povazay B, Prashar A, To CH, Erichsen JT, Feldkaemper M, Hofer B, Drexler W, Schaeffel F, Guggenheim JA
Corneal volume measures for monitoring contact lens induced corneal swelling: a pilot study. Clin Exp Optom 2011;94:93-97.  Lam AK, Wong YZ, Cheng SY 
PAX6 Haplotypes Are Associated with High Myopia in Han Chinese. PLoS One 2011;6:e19587.  Jiang B, Yap MK, Leung KH, Ng PW, Fung WY, Lam WW, Gu YS, Yip SP 
Impairment of retinal adaptive circuitry in the myopic eye. Vision Res 2011;51:367-75. Ho WC, Ng YF, Chu PH, Fong YY, Yip KS, Kee CS, Chan HH  
Forward and backward adaptive effects in global flash multifocal electroretinogram stimulation. Clin Exp Optom 2011;94:259-67.  Chu PH, Ng YF, Chan HH 
Bifocal lens control of myopic progression in children. Clin Exp Optom 2011;94:24-32.  Cheng D, Woo GC, Schmid KL
Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese. J Zhejiang Univ Sci B 2010;11:836-41.  Yu YS, Wang LL, Shen Y, Yap MK, Yip SP, Han W 
Discontinuation of orthokeratology and myopic progression. Optom Vis Sci 2010;87:1053-6.   Lee TT, Cho P 
Correctable visual impairment among people with diabetes in Hong Kong. Clin Exp Optom 2010;93:453-57.  Fung MMY, Yap MKH, CHENG KKY 
Retinal thickness in myopic and non-myopic eyes. Ophthalmic and Physiological Optics 2010;30:776-84. Cheng SCK, Lam CSY, Yap MKH
Factors affecting accuracy in the Developmental Eye Movement Test measurement for Cantonese-speaking children. Clin Exp Optom 2010;93:341-48. Pang PC, Lam CS, Woo GC 
The Developmental Eye Movement (DEM) test and Cantonese-speaking children in Hong Kong SAR, China. Clin Exp Optom 2010;93:213-23.   Pang PC, Lam CS, Woo GC  
Effects of luminance combinations on the characteristics of the global flash multifocal electroretinogram (mfERG). Graefes Arch Clin Exp Ophthalmol 2010;248:1117-25.  Lung JC, Chan HH 
Relationship between corneal topographical changes and subjective myopic reduction in overnight orthokeratology: a retrospective study. Clin Exp Optom 2010;93:237-42.     Chan B, Cho P, Mountford J  
Alternating monovision contact lens wear arrested fast progressing myopia. Clinical & Refractive Optometry 2010;21:38-41. Lo P, Tse DY, Lam CSY, To CH 
New applications in the corneal topography system. Expert Rev Ophthalmol 2010;5:115-17.  Lam A
Randomized trial of effect of bifocal and prismatic bifocal spectacles on myopic progression: two-year results. Arch Ophthalmol 2010;128:12-9. Cheng D, Schmid KL, Woo GC, Drobe B
Sex, eye size, and the rate of myopic eye growth due to form deprivation in outbred white leghorn chickens. Invest Ophthalmol Vis Sci 2010;51:651-7. Chen YP, Prashar A, Hocking PM, Erichsen JT, To CH, Schaeffel F, Guggenheim JA
Posterior corneal curvature change and recovery after 6 months of overnight orthokeratology treatment. Ophthal Physiol Opt 2010;30:274-80. Chen D, Lam AKC, Cho P
Practitioners' analysis of contact lens practice in Hong Kong. Cont Lens Anterior Eye 2010;33:104-11.    Charm J, Cheung SW, Cho P 
Do multipurpose contact lens disinfecting solutions work effectively against non-FDA/ISO recommended strains of bacteria and fungi? Ophthalmic Physiol Opt 2010;30:12-9. Boost M, Lai S, Ma C, Cho P  
Fitting kids with contact lenses. Contact Lens Spectrum 2009  Cho P, Cheung SW 
Non-compliance and microbial contamination in orthokeratology. Optom Vis Sci 2009; 86: 1227-1234 (2009) Cho P, Boost M, Cheng R
Rivers and mountains may change, human nature does not! (traditional Chinese saying). Cont Lens Anterior Eye 2009; 32: 155-156 (2009) Cho P, Boost M
Effect of cycloplegia on axial length and anterior chamber depth measurements in children. Clin Exp Optom 2009; 92: 476-481 (2009) Cheung SW, Chan R, Cheng RC, Cho P
Toric orthokeratology: a case report. Clin Exp Optom 2009; 92: 387-391 (2009)  Chan B, Cho P, de Vecht A 
TGFB1 as a susceptibility gene for high myopia: a replication study with new findings. Arch Ophthalmol 2009; 127: 541-548 (2009) Zha Y, Leung KH, Lo KK, Fung WY, Ng PW, Shi MG, Yap MK, Yip SP
Thyroid disease induced diplopia. Clin Exp Optom 2009; 92: 30-33 (2009) Law KM, Woo GC
Monochromatic aberrations of the human eye and myopia. Clin Exp Optom, Vol. 92, pp. 304-312(2009) 


A pilot study on the corneal biomechanical changes in short-term orthokeratology. Ophthal Opt, Vol. 29, pp. 464-471 (2009) CHEN D., LAM A.K.C., CHO P.
Soft contact lens cleaning: rub or no-rub? Ophthalmic Physiol Opt, Vol. 29, pp.49-57 (2009) CHO P., CHENG S.Y., CHAN W.Y., YIP W.K.
Reliability and repeatability of the Pentacam on corneal curvatures. Clin Exp Optom, Vol. 92, pp. 110-118 (2009) CHEN D., LAM A.K.C.