School of Optometry 眼科視光學院
Home About Us What's New Subscribe eNewsletter Contact Us My School 繁體 简体 Text Only Print
About us
Message from Head of School
Vision & Mission
Our People
Academic Staff
Affiliate Faculty Members
Honorary & Adjunct Professor
Visiting Staff & Academic Visitors
Optometry Clinic Staff
Research Staff
Research Students
Our Research
About us > Our People > Research Students > Mr. YANG Xiayin
Our People
Mr. Chunghim SO | Mr. Dong LIANG | Mr. Milan RAI | Ms. Jing ZHANG | Ms. Shuwen JIA | Ms. Wing Yan LAU | Ms. Yingkun CUI | Ms Jingfang Jennifer BIAN | Mr Shashi Kant CHAUDHARY | Ms Meng CHENG | Mr Ka Wai Jimmy CHEUNG | Ms Hang I Christie LAM | Ms Hoi Lam LI | Ms Sonal Aswin VYAS | Mr Kin Ken WAN | Ms Biyue GUO | Ms Li PAN | Ms Qi TAN | Mr Mezbah UDDIN | Ms Rong LI | Ms. Yuanyuan LIANG | Ms Anqi LYU | Mr Ying Hon SZE | Ms Qin WANG | Ms Hanyu ZHANG | Ms Wei YANG | Ms Mei ZHAO | Ms Yajing YANG | Ms Fangyu XU | Mr Sung Hei Jimmy TSE | Ms. Seen Hang CHAN | Mr. CHAN Kin Ho | Ms. AYERAKWAH Patience Ansomah | Mr. SO Ching | Mr. CATRAL Kirk Patrick Carreon | Mr. LIU Zhengji | Mr. LU Daqian | Ms. QIU Chunting | Mr. YANG Xiayin

Mr. YANG Xiayin

Mr. YANG Xiayin
PhD Student

ORCiD 0000-0002-5229-3509

Title of project:
Longitudinal assessment of optic nerve neurodegeneration using rodent models of demyelinating optic neuritis

Demyelinating optic neuritis is an inflammatory condition on optic nerves and common in East Asian populations. It happens in different pathological conditions, for example, neuromyelitis optica spectrum disorder or multiple sclerosis. The current immunosuppressive therapies cannot provide a good visual outcome in a part of patients with demyelinating optic neuritis. Consequently, it may result in irreversible impairment of vision. The pathophysiology of demyelinating optic neuritis still remains unclear currently. The laboratory and clinical investigations of this disease in Asian populations, and especially in Chinese people, are needed.

In this project, we try to have a better understanding and observation in development of demyelinating optic neuritis based on the novel rodent models, and monitor the longitudinal structural changes in axonal injury in demyelinating optic neuritis using optical coherence tomography and electrophysiological techniques. This study will provide an ideal platform for follow-up studies on the characteristics, pathogenesis and new therapeutic development in relation to optic neuritis.