耆年健康

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主要研究員:
梁綺雯教授(教授)
雷逸華博士(副教授)
謝敏儀博士(副教授)
關耀祖博士(助理教授)
林清博士(助理教授)
張詩琪博士(助理教授)
賴錦玉博士(榮譽教授)
重點研究
過去十五年,研究團隊重點研究如何關顧認知障礙人士及其照顧者。我們識別及推廣最佳實踐,以關顧輕度認知障礙人士,認知障礙症患者,及其照顧者(護理助理員)的健康需要。
認知障礙人士的健康狀況和護理需要
研究團隊識別專為認知障礙人士而設的干預措施並試驗其效果。我們與香港園藝協會 (譯名) 合作進行一項探索性研究,評估園藝療法對認知障礙症患者的情緒和行為的初步影響(關耀祖博士)。研究並擴展至以護養院體弱和體弱前期長者為對象(關耀祖博士)。
健康識能研究—認知障礙症健康識能
促進健康和公共教育的第一步是了解市民對認知障礙症的認識水平及尋求資訊以支援認知障礙症患者的意願。在柬埔寨、菲律賓、斐濟、內地和香港五個地方分別進行以人口為基礎的調查,以了解市民的認知障礙症健康識能水平(梁綺雯教授)。研究結果有助各國政府制定相關政策和方法,教育公眾如何支援認知障礙症患者及其護理助理員。
賴錦玉博士及其團隊進行了一項Cochrane論文回顧,題為 “關顧有行為問題認知障礙症患者的特殊護理部門”。結果顯示認知障礙症患者的護理應正常化(以特殊護理部門關顧認知障礙症患者的益處不顯著)。賴博士的論文受國際研究人員引用共97次。此外,賴博士有關懷緬療法的研究也影響全球和本地的照護實踐。
干預方案研究—支持關顧認知障礙症患者
團隊進行一系列研究以評估為認知障礙症患者設計的干預方案是否可行及有效。我們測試了穴位按壓對紓緩認知障礙症患者躁動和壓力的成效(關耀祖博士和賴錦玉博士),並指出音樂律動干預適用於中度認知障礙症患者(張詩琪博士)。此外,我們觀察疼痛情況,進行一系列有關認知障礙症患者疼痛管理的研究,探討方案的可行性和可接受程度後才制訂全面的 “觀察及管理疼痛方案”。在2014年,團隊以患有晚期嚴重認知障礙症院友為對象,在17間護養院進行隨機對照試驗。研究證明“觀察及管理疼痛方案”的成效(雷逸華博士及賴錦玉博士)。
[R1] Lai, C.K.Y., Ho, L., Kwan, R.Y.C., Fung, C., & Mak, Y.W. (2016). An exploratory study on the effect of horticultural therapy for adults with intellectual disabilities. Journal of Therapeutic Horticulture, 26(2), 3-15.
[R2] Lai, C.K.Y., Kwan, R.Y.C., Lo, S.K.L., Fung, C.Y., Lau, J.K., & Tse, M.M.Y. (2018). Effects of horticulture on frail and pre-frail nursing home residents: a randomized controlled trial. JAMDA, doi: 10.1016/j.jamda.2018.04.002 (Impact Factor: 5.775)
[R5] Liu, J.Y.W. & Lai, L.K.C. (2014). Implementation of an observational pain management protocol to improve pain management for long-term institutionalized older care home residents with dementia: study protocol for a cluster-randomized controlled trial.BMC. Trials,15:78. doi:10.1186/1745-6215-15-78. [Impact factor: 1.969; Citation 13]
[R6] Lai CK, Chi I, Kaywer-Jones J. (2004). A randomized controlled trial of a specific reminiscence approach to promote the well-being of nursing home residents with dementia. International Psychogeriatriacs, 16(1), 33-49. doi: 10.1017/s1041610204000055.
[R7] Lai CKY, Yeung JHM, Mok V, Chi I. Special care units for dementia individuals with behavioural problems (Review). Cochrane Library. Cochrane Database of Systematic Review 2009, Issue 4. Art. No.: CD006470. DOI: 10.1002/14651858.CD006470.pub2.https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD006470.pub2/epdf/abstract
[R8] Leung, A. Y. M., Molassiotis, A., Zhang, J., Deng, R., Liu, M., Van, I. K., Leung, I. S. H., Loke Yuen, A. (2020). Dementia literacy in the Greater Bay Area of China: Challenges and opportunities.International Journal of Environmental Research and Public Health (IJERPH). Special Issue: Health literacy and Equity, 17(7),2511.https://doi.org/10.3390/ijerph17072511(Impact Factor: 2.468)
[R9] Leung, A. Y. M., Leung, S. F., Ho, G.W.K., Bressington, D., Molassiotis, A., Lam, C., Ligot, J., Valdez, L. P., Lazalita, A., Chhit, S., Chou, P., Valimaki, M. (2019). Dementia literacy in Western Pacific Countries: A mixed-method study.International Journal of Geriatric Psychiatry,1-11. doi: 10.1002/gps.5197 (Impact Factor: 3.141)
1. 主要影響
根據賴錦玉博士的研究工作,Haslam及其研究小組(2010)提出在護養院以緬懷療法作為認知障礙症患者的“社會治療”,並進一步探討療法中哪些是關鍵及使院友得益的必須包括部分[S1]。賴博士的研究貢獻在於促進整合分析認知刺激療法如何影響認知。(《柳葉刀》認知障礙症預防,干預和照護委員會,2017年)[S2],並促成制定認知刺激療法的指引和建議。梁綺雯教授及其團隊全面審核了認知障礙症的評估和診斷。該回顧論文刊登於《香港醫學雜誌》(Hong Kong Medical Journal,2019年12月) 並獲選為香港醫學專科學院的持續醫學教育/持續專業發展教材,使至少700名院士和其他非院士接受相關的認知障礙症治療培訓。
2. 影響服務
賴錦玉博士、關耀祖博士及其團隊制定園藝治療方案,在研討會上公布成效後,獲得博愛醫院護理安老院採用 [S3]。園藝治療方案在三間護養院推行,成為常規活動,包括:楊晉培護理安老院、博愛醫院戴均護理安老院、以及博愛醫院賽馬會護理安老院。每間護養院把某角落改為小花園,每天由十名院友照顧植物。張詩琪博士和賴錦玉博士的音樂律動方案以89名照顧者和86名長者社區中心的職員為對象。九間長者社區中心採用方案,共有804名認知障礙症患者在中心參加了音樂律動活動。團隊以巡廻路演和講座方式宣傳音樂律動的成效,共接觸了1,191名公眾。到2018年3月,相關的電子書錄得80次下載。團隊在2018年獲135萬港元資助把方案轉化為可實踐形式。捐款協助我們培訓了140名義工,90名照顧者和75名中心職員,使75個家庭受惠。此外,八間護養院採用了雷逸華博士的 “觀察疼痛方案” ,133名院友和340名照顧員得益。
為在本地實踐緬懷療法,賴錦玉博士舉辦工作坊培訓了275人(85名大學生,160名社會工作者/護士和30名長者)。參加者完成培訓後在社區長者中心提供緬懷治療服務。
3. 影響社會
以上研究引起政府官員和服務提供者注意。香港政府廣播電台邀請我們向社區廣播述說團隊的研究成果:在2018年我們參與製作了26集節目,1,200名網上課程註冊學生和十萬名公眾收聽(梁綺雯教授,雷逸華博士,關耀祖博士,以及張詩琪博士)。這26集節目的內容都是有關團隊的認知障礙研究,如:認識認知障礙症狀,用科技為輕度認知障礙長者解決日常生活問題,按壓處理老年認知障礙症狀(長者躁動),預防認知障礙症,認知障礙症患者照顧,使用靜觀干預來管理認知障礙症患者照顧者的壓力[S4]。
4. 影響政策
世界衛生組織委託團隊在西太平洋國家展開了認知障礙症識能水平的研究調查。此外,我們另一項目是研究內地大灣區的認知障礙症識能水平(梁綺雯教授)。研究結果有助各國制訂政策和認知障礙症服務。廣東省政府認同研究結果並支持團隊於2019-2020年在珠海、香港和澳門分別舉辦各種提升公眾認識認知障礙症的教育計劃。此外,25個老年護理學單位組成聯盟以促進珠海的認知障礙症護理,並由梁綺雯教授擔任聯盟的顧問。香港政府於2020年委託團隊進行一個顧問研究,以評估照顧者的需要和服務,以助制定相關政策(梁綺雯教授)。
S1. Haslam C, Haslam SA, Jetten J, Bevins A, Ravenscroft S. et al. (2010). The social treatment: The benefits of group interventions in residential care settings. Psychology and Aging, 25(1), 157-167. DOI:10.1037/a0018256
S2. https://www.nari.net.au/files/files/documents/lancet_commission.pdf
S3. The Newsletter of the Hong Kong Association of Horticultural Therapy (p.18):http://www.hkath.org/wp-content/uploads/2018/06/HKATH-newsletter-issue-12.pdf
S4. A link showing the recording of the episodes in Radio 5, Hong Kong:https://www.rthk.hk/radio/radio5/programme/elderly_selfmanagement
S5. Leung, A. Y. M. (2019 Feb 24-26). The 2nd Guangdong-Hong Kong-Macao Greater Bay Area Health Cooperation Conference. Health Commission of Guangdong Province, Food and Health Bureau of the Government of Hong Kong SAR, Health Bureau of Macao SAR Government, and Shenzhen Municipal People’s Government. Shenzhen, China. The project ‘Promoting dementia literacy in Zhuhai and Hong Kong’ was selected as the listed project.
S6. Lam, K., Chan, W. S. Y., Luk, J. K. H., Leung, A. Y. M.* (2019). Assessment and diagnosis of dementia: A review for primary health care professionals.Hong Kong Medical Journal, 25(6),473-82.https://doi.org/10.12809/hkmj198073(Impact Factor: 1.588).https://www.hkmj.org/system/files/cme1912.pdf
在學研究生
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- mining.liang@connect.polyu.hk
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校外資助計畫
Effects of Facebook-based bibliotherapy on improving the wellbeing of informal caregivers of people with dementia: a pilot randomized controlled trial
Investigators Name:
PI: Dr Shan Shan WANG
Co-I: Prof. Yee Man LEUNG, Dr Sze Ki CHEUNG, Ms Ka Yu WONG, Mr Sze Him LEUNG
Funding Scheme/ Source of Funding: NICHE Research Grant
Total Grant: HK$120,000
Commencement Date: 14-Feb-22
The Effects of a Hybrid Face-To-Face and Online Mode of Delivering a Mindfulness-Based Dementia Caregiving Programme for Family Caregivers of Persons with Dementia: A Randomized Controlled Trial
Investigators Name:
PI: Dr Pui Kin KOR
Funding Scheme/ Source of Funding: RGC Early Career Scheme
Total Grant: HK$785,120
Commencement Date: 1-Jan-22
Background
Dementia is a worldwide public health priority affecting over 50 million people. Demanding caregiving tasks and uncertainty about the progression of the disease invariably leads to high levels of stress in family caregivers of people with dementia (PWD), consequently posing a threat to their health and dyadic relationship. In various studies, mindfulness-based interventions (MBI) demonstrated promising results on reducing stress. However, a few limitations were noted. First, previous MBIs required the involvement of a qualified interventionist with rigorous training in mindfulness (e.g., 2–3 years), which would impede popularization of the use of mindfulness. Second, the high-intensity training (e.g., 26 hours over 8 weeks in a Mindfulness-based Stress Reduction Programme) that was involved would not be cost-effective enough to accommodate the increasing number of caregivers. Also, caregivers who are heavily engaged in caring tasks will encounter difficulty in attending face-to-face training programmes. Lastly, the MBIs were not tailor-made for dementia caregiving, so the teaching was not linked with caregiving components (e.g., how to respond mindfully to the behavioural problems of the care-recipient). It is necessary to develop a simplified mindfulness programme for caregivers of PWD that can be delivered flexibly by non-mindfulness professionals and integrated with caregiving contents.
Objective
To investigate the effectiveness of a hybrid face-to-face and online mode of delivering a Mindfulness-Based Dementia Caregiving Programme (MBDCP) for reducing stress in family caregivers of PWD.
Methods
In this two-arm, randomized controlled trial, 290 family caregivers of PWD will be recruited and randomized to either the intervention group, receiving the 6-session (1.5 hours each) MBDCP programme over 6 weeks; or the control group, receiving a brief education programme on dementia. The 1st, 2nd, and 6th sessions and the 3rd, 4th, and 5th sessions will be delivered face-to-face and online respectively in both arms. The outcomes will be measured immediately post-intervention (T1) and at the 6-month follow up (T2), and compared with the baseline (T0). They include perceived stress (primary outcome), depressive symptoms, the positive aspect of caregiving, caregiving burden, dyadic relationship, level of mindfulness, the heart rate variability of the caregivers, and the neuropsychiatric symptoms of the care-recipients. A Generalized Estimating Equation will be performed to assess the effects of time, group, and time-group interaction on all outcome measurements. This study will be a pioneering interventional study on adopting brief mindfulness training (MBDCP) with a hybrid delivery approach to reduce the stress in family caregivers of PWD.
Effectiveness of a dyadic pain management program for community-dwelling older adults with chronic pain: a cluster randomized controlled trial
Investigators Name:
PI: Dr Mun Yee Mimi TSE
Co-I: Prof. Sheung Mei NG, Dr Vivian LOU
Funding Scheme/ Source of Funding: Health and Medical Research Fund (HMRF)
Total Grant: HK$1,499,254
Commencement Date: 1-Dec-21
Objective: To evaluate the effectiveness of a Dyadic pain management program (DPM) in reducing pain and psychological health symptoms, improving pain self-efficacy, quality of life, and physical function in older adults.
Hypothesis: DPM is more effective in reducing pain and psychological health symptoms, improving pain self-efficacy, quality of life, and physical function among older adults than the usual care, upon completion of the DPM (week 8) and over time (week 16).
Design and subjects: Clustered randomized controlled trial with neighborhood elderly centers (NEC) as cluster; 150 dyads (one older adults and his/her caregiver as one dyad) will be recruited from 22 NEC clusters. Each NEC will be randomly allocated to experimental group (receive DPM), control group (receive usual care and pain management pamphlet).
Study instruments: Brief Pain Inventory; Pain Self-Efficacy Questionnaire; Short Form Health Survey-12; Depression, anxiety & stress; Caregiver Burden Inventory; 6-minute walk test and process evaluation.
Intervention: DPM, each session includes exercise, interactive pain management education, practices on non-drug techniques and using a WhatsApp group to encourage home-based exercise and practice of non-drug methods.
Outcome measures: Pain intensity, pain self-efficacy, perceived health-related quality of life and experience in participating DPM, to be collected at baseline (T0), week 8 (T1), and week 16 (T2).
Data analysis: Multilevel regression and/or Generalized Estimating Equation will be used for within-group and between- group comparisons.
Expected results: Significant reduction in pain and enhancement in pain-related parameters, enforcing dyadic pain management models in elderly care.
Using a web-based mind-body intervention program for reducing stress in family caregiver of frail older people in mainland China: an intervention protocol development
Investigators Name:
PI: Dr Pui Kin KOR
Funding Scheme/ Source of Funding: 鄭州悅來蘋果酒店有限公司
Total Grant: HK$20,000
Commencement Date: 1-Aug-21
Development and validation of a holistic health literacy scale for family caregivers of older people
Investigators Name:
PI: Dr Pui Kin KOR
Co-I: Dr Ching LAM, Dr Hong LEE, Dr Yee Man Angela LEUNG, Dr Yat Wa Justina LIU, Ms Ka Ching LEE
Funding Scheme/ Source of Funding: NICHE Research Grant
Total Grant: HK$142,591
Commencement Date: 1-Jan-21
Evaluation of the filtering efficiency, fit rate and mask usability of two newly developed N95 respirators
Investigators Name:
PI: Dr Ching LAM
Co-I: Ms Suk Ki HO, Miss Ka Yan KO, Mr Kam Hung LAI, Ms Wing Yee NG, Dr Kwai Ping Lorna SUEN, Dr Yiu Wan YIP
Funding Scheme/ Source of Funding: Vannex International Ltd
Total Grant: HK$543,720
Commencement Date: 5-Nov-20
Establishment of testing laboratory and investigation of the trends of quality of filtering facemask during and after the COVID-19
Investigators Name:
PI: Dr Ching LAM
Co-I: Ms Suk Ki HO, Prof. Chi Wai KAN, Miss Ka Yan KO, Dr Kit Hang SIU, Dr Kwai Ping Lorna SUEN
Funding Scheme/ Source of Funding: Hip Seng Quality Advancement Centre Company Limited
Total Grant: HK $4,722,000
Commencement Date: 1-Oct-20
Disinfection and reuse of face masks in community setting during COVID-19 epidemic: An experimental study design
Investigators Name:
PI: Dr Ching LAM
Co-I: Dr Kwai Ping Lorna SUEN, Dr Kit Hang SIU
Funding Scheme/ Source of Funding: New World Construction Company Limited
Total Grant: HK$350,020
Commencement Date: 1-Aug-20
Investigation of Happiness Index and its Explanatory Model in Hong Kong: Repeated Cross-sectional Studies
Investigators Name:
PI: Dr Ching LAM
Co-I: Dr Sze Ki CHEUNG, Dr Hok Man HO, Ms Cho Nga SIU
Funding Scheme/ Source of Funding: Wofoo Foundation Limited
Total Grant: HK$300,000
Commencement Date: 31-Mar-20
Effectiveness of the Nurse-led Support Programme Using a Mobile Application Versus Telephone Advice on Patients at Risk of Coronary Heart Disease - A Pilot Randomized Controlled Trial
Investigators Name:
PI: Dr Mi Ling Eliza WONG
Co-I: Dr Shuk Yee KO, Dr Ching LAM, Dr Lap Yip Larry LEE, Dr Yee Man Angela LEUNG, Dr Yin Ping LEUNG
Funding Scheme/ Source of Funding: Nam Kee Noodle Foundation Ltd
Total Grant: HK $270,000
Commencement Date: 1-Mar-20
The study aims to compare the effects of a nurse-led support programme using a mobile application versus telephone advice on clients at risk of coronary heart disease .
Methods
A multi-centre, single-blinded, randomized controlled trial will be conducted. 60 clients diagnosed as being at risk of CHD, able to use a smart phone will be randomized into the App Support Programme (ASP) group or the Telephone Support (TS) group. All participants will receive usual medical treatment as prescribed by doctors . The ASP group will receive an app whereas the TS group will receive telephone support provided by the nurse for 20 minutes bi-weekly. The self-developed mobile app will support clients in managing their health problems and lifestyle. It is comprised of: (1) a knowledge health platform, (2) a membership area for individual health measures and exercise records, (3) a Chest Pain – Things to Do List, and (4) an individual reminder and measure feedback system.
Health outcomes will be collected at baseline (T0), 1 months (T1), 3 months (T2). The primary outcome is: Self-efficacy and self-management behaviour. Secondary outcomes are: (i) ED and hospitalization frequency; (ii) Physiological health profile and cardiovascular functional endurance; (3) total amount of exercise; (4) perceived stress level; and (6) quality of life.
Data analysis: A Generalized Estimating Equations model will be used to assess differential changes in all outcome variables.
Significance:
Coronary heart disease (CHD) is a major chronic disease around the world and in Hong Kong, and secondary prevention is important to reduce the impact of CHD and to slow its progression via early detection and treatment. Strategies to improve secondary care and support have become a priority of government health policies and healthcare strategies in Hong Kong and many other countries.
This pilot study will examine the feasibility of the main RCT study by using the app; identify any recruitment, implementation of intervention and logistic issues arising from the recruitment, intervention and follow-ups. It can also provide the preliminary finding for sample size calculation for the main RCT.
Investigation of Happiness Index in the Guangdong-Hong Kong-Macau Greater Bay Area in Southern China: Three Phases Study
Investigators Name:
PI: Dr Ching LAM
Co-I: Dr Sze Ki CHEUNG, Dr Yun GAO, Dr Ning LAU, Dr Yim Wah MAK, Dr Mun Yee Mimi TSE, Ms Janny XIE, Prof. Ying ZHOU
Funding Scheme/ Source of Funding: Shih Wing Ching Foundation Limited
Total Grant: HK$75,000
Commencement Date: 1-Mar-20
Virtual Reality Motor-cognitive Training for Older People with Cognitive Frailty
Investigators Name:
PI: Dr Yiu Cho KWAN
Co-I: Dr Nai Kuen FONG, Prof. Claudia Kam Yuk LAI, Dr Yat Wa Justina LIU, Ms Shuk Kan Olive SIN, Dr Jing QIN
Funding Scheme/ Source of Funding: Innovation and Technology Fund for Better Living
Total Grant: HK$2,537,500
Commencement Date: 1-Jan-20
Introduction
Cognitive frailty is an at-risk state of dementia. Motor-cognitive training is effective to promote cognitive and physical function. However, the ecological validity of conventional motor-cognitive training is questionable. Virtual reality (VR) aims to increase the extent of effect transfer from a lab setting to the daily living settings. However, the effect and ecological validity of the virtual reality-based motor-cognitive training in older people with cognitive frailty is unknown.
The objectives of this study are to examine the effects of the VR motor-cognitive training on:
1. cognitive function,
2. frailty syndrome,
3. physical activity level in daily living, and
4. life-space in daily living
Methods
A wait-list multi-centred randomized controlled trial will be employed. Subjects will be randomized into either the intervention group or control group in 1:1 ratio. Subjects will be recruited in the community settings in the elderly community centres. Eligibility criteria include 1) age ≥ 60 years, 2) community-dwelling, 3) cognitive frailty, 4) no dementia, & 5) functional level at outdoor walker level. In the intervention group, the subjects receive VR motor-cognitive training which lasts for eight weeks, provides two sessions per week, and provides 30 minutes per session. In the control group, the subjects receive usual care provided by the elderly community centres (e.g., unsupervised ergometer cycling, board games). Outcome measures include 1) cognitive function as measured by Montreal Cognitive Assessment, 2) frailty as measured by Fried Frailty Phenotype scale, 3) physical activity as measured by actigraph, and 4) life-space as measured by GPS lodger. We aim to recruit 648 subjects in not-less-than six community elderly centres. Data collection will be conducted at baseline (T0) and the week immediately after the intervention (T1). Data will be analysed by using IBM SPSS version 25.0. ANOVA will be used to estimate the interaction-group, between-group, and within-group effects on the outcomes. Principle of intention-to-treat analysis will be adopted to interpret the results. Missing data will be replaced by the last observed values.
Significance
If the intervention is effective, there is going to be a brand new community-based training for community-dwelling older people with cognitive frailty to reduce their cognitive frailty, so as their risk of dementia.
Good Dyadic Relationship between Couple with One Having Mild Cognitive Impairment: a Q-methodology
Investigators Name:
PI: Dr Sze Ki CHEUNG
Co-I: Dr Daniel Thomas BRESSINGTON, Dr Hok Man HO, Dr Wing Ka Grace HO
Funding Scheme/ Source of Funding: NICHE Research Grant
Total Grant: HK $111,000
Commencement Date: 1-Oct-19
A Multicentre Randomized Controlled Trial of the Effectiveness of a Lifestyle Intervention Programme Using Mobile Application Vs Booklet for Adults with Metabolic Syndrome
Investigators Name:
PI: Dr Mi Ling Eliza WONG
Co-I: Dr Yee Man Angela LEUNG, Dr Yin Ping LEUNG
Funding Scheme/ Source of Funding: Health and Medical Research Fund (HMRF)
Total Grant: HK $1,254,142
Commencement Date: 1-Jul-19
Aims The study aims to compare the effect of a lifestyle intervention programme (LIP) using mobile application (MetS app) vs using booklet for MetS adults living in the community.
Methods A multi-site randomized controlled trial (RCT) with three arms, namely, MetS app group (Group A), booklet group (Group B), and control group (group C). Two hundred and sixty four subjects will be recruited from community centers and randomized into either one arm. Inclusion criteria are those MetS adult, able to use a smart phone. Group a participants will receive a 30-minute educational session and a MetS app while Group B will receive same educational session and a MetS booklet and the control group receive a placebo booklet only. The MetS app or booklet, has been well developed by the team with the support of internal grant, aims to support MetS individual’s self- monitoring and record of health measures (body weight, blood pressure, waist circumference) and exercise. The primary outcomes of this study include the body weight and total physical exercise (GSLTPAQ). The secondary outcomes include cardiometablolic risk factors, cardiovascular endurance, self-efficacy for exercise (SEE) and stress level (PSS-10). Data will be collected at baseline (T1), 4 week (T2) and week 12 (T3) and week 20 (T4). SPSS and Generalized Estimating equations (GEE) model will be employed for data analysis.
Significance This study will provide empirical evidence and inform about the effective way to enhance patient’s self-management of MetS, exercise sustainability that will be beneficial to clients’ health.
Effectiveness of a Peer-Led Pain Management Program in Relieving Chronic Pain and Enhancing Pain Self-Efficacy Among Older Adults: Clustered Randomized Controlled Trial
Investigators Name:
PI: Dr Mun Yee Mimi TSE
Co-I: Dr Xue BAI, Dr Hong LEE, Dr Raymond See-kit LO, Dr Sheung Mei Shamay NG
Funding Scheme/ Source of Funding: Health and Medical Research Fund (HMRF)
Total Grant: HK $1,044,390
Commencement Date: 3-Jul-18
Effects of a Modified Mindfulness-based Cognitive Therapy for Family Caregivers of People with Dementia in Stress Reduction: a Pilot Randomized Controlled Trial
Investigators Name:
PI: Mr Pui Kin KOR
Co-I: Dr Yat Wa Justina LIU, Prof. Wai Tong CHIEN
Funding Scheme/ Source of Funding: Sigma Theta Tau International
Total Grant: HK $39,150
Commencement Date: 1-Jun-18
Partnership with the Community to Improve the Psychosocial Well-being of People with Dementia or Mild Cognitive Impairment, and their Caregivers with Music Interventions: an Effectiveness-Implementation Cluster Randomized Clinical Trials
Investigators Name:
PI: Dr Sze Ki CHEUNG
Co-I: Mr Daniel LAI, Miss Yuen Wah HO, Prof. Claudia Kam Yuk LAI
Funding Scheme/ Source of Funding: Ho Cheung Shuk Yuen Charitable Foundation
Total Grant: HK $1,354,502
Commencement Date: 1-Feb-18
Evaluation of an Individualized Exercise Programme Plus Behavioural Change Enhancement Strategies for Managing General Fatigue in Community-Dwelling Frail Older People: A Cluster-Randomized Controlled Trial.
Investigators Name:
PI: Dr Yat Wa Justina LIU
Co-I: Dr Parco Ming-fai SIU, Prof. Wai Tong CHIEN, Prof. Keith HILL
Funding Scheme/ Source of Funding: General Research Fund
Total Grant: HK $853,463
Commencement Date: 1-Jan-18
Project on Medication Adherence and Health Literacy - Part 2
Investigators Name:
PI: Dr Yee Man Angela LEUNG
Co-I: Dr Tak Yin LAU, Dr Yat Wa Justina LIU, Ms Shuk Man Sylvia TING
Funding Scheme/ Source of Funding: Hong Kong Housing Society
Total Grant: HK $100,000
Commencement Date: 18-Sep-17
Objectives: This project is the extension of the previous study (MAHL). It aims to compare the effect of verbal advice with the effect of comic books on medication adherence and health literacy among older residents in the 15 public estates in Hong Kong, and to develop a protocol for home-based nursing counselling in medication adherence and assess its implementation.
Methods: This is a three-phase multi-site study with pre-and-post measures. Phase 1 consists of two 45-minute home visits to each older resident by Mediation Use Supportive Team (MUST) team members. A designated protocol will be developed to guide the MUST team members’ action/health education. Phase 2 consists of another two 45-minute home visits in which health literacy skills training and clarification of the misunderstanding of drug labels, appointment sheets and use of common drugs will be included. A comic book will used. Phase 3 consists of 3-hour contacts (two 1-hour home visits, phone counselling and whatsapp messaging) by an experienced nurse. We will reach 300-350 older residents in Phase 1 and Phase 2 respectively, while 25 older residents in Phase 3. Measures include medication knowledge and compliance scale (MKCS) and Chinese Health Literacy Scale for Chronic Care (CHLCC).
Significance of the study: This study provides evidence of the use of verbal advice, comic books, and home-based nursing counselling in medication compliance and health literacy.
Promoting Mental Health Literacy in Aging: Identifying Depressive Symptoms Through Photos
Investigators Name:
PI: Dr Yee Man, Angela LEUNG
Co-I: Dr Pui Hing CHAU, Ms Angel Fung-man CHAN, Ms Wai Ming TAM, Prof. Wai Tong CHIEN
Funding Scheme/ Source of Funding: Health Care & Promotion Fund (Seed Funding)
Total Grant: HK $493,863
Commencement Date: 1-May-17
Background: Many older adults experience loneliness and depression but they do not often express their feelings, particularly in Chinese population.
Aim: This project aims to promote older adults’ mental well-being and develop their capacity to seek for mental health advices. Design: This is a community-based participatory project encouraging older participants to take photos to share and express their feelings. Their mental health issues will be explored and discussed in meetings with their community workers. These older adults will then be supported to seek for advices on mental health promotion.
Subjects: A total of 460 older adults will be guided by 46 community workers to take photos in the neighbourhood and share their feelings.
Significance: This project contributes to better understanding of mental health issues in older adults, enhancing psychosocial support and health seeking for promotion of mental health/well-being. Participants’ quality of life will be assessed to evaluate its effect.
Genetic Analysis of Alzheimer's Disease in Hong Kong (Sub-account of 5-ZJL7)
Investigators Name:
Rep Co-PI: Dr Yee Man Angela LEUNG
Co-PI: Dr Lok Ting LAU
Co-I: Dr David DAI, Dr Yiu Cho KWAN
Funding Scheme/ Source of Funding: Donation from Individuals
Total Grant: HK $165,663
Commencement Date: 6-Mar-17
Objectives: This study aims to validate genetic variants in APOE gene that are associated with the risk of late-onset Alzheimer’s disease in Hong Kong, perform whole-exome search for genetic variants that are associated with the risk of late-onset Alzheimer’s disease in Hong Kong, and identify factors or lifestyle associated with genetic variants.
Method: We will recruit 300 local Chinese persons, 100 with clinically diagnosed with AD, 100 with mild cognitive impairment and 100 with normal cognition. A comprehensive health survey will be conducted by trained research assistants. The environmental and psychosocial factors associated with AD and cognitive frailty will be included in the survey. Buccal swab samples will be collected and DNA will be extracted.
Significance of the study: The findings of the study will inform us the genetic variants in persons with late-onset of Alzheimer’s disease and the factors associated with these genetic variants.
Project on Medication Adherence and Health Literacy
Investigators Name:
PI: Dr Yee Man Angela LEUNG
Co-I: Dr Yat Wa Justina LIU
Funding Scheme/ Source of Funding: Hong Kong Housing Society
Total Grant: HK $99,475
Commencement Date: 15-Sep-16
Objectives: This project aims to assess the effect of comic books on medication adherence and health literacy among older residents in the 15 public estates in Hong Kong.
Methods: This is a multi-site study with pre-and-post measures. Phase 1 consists of two 45-minute home visits to each older resident by Mediation Use Supportive Team (MUST) team members. Phase 2 consists of another two 45-minute home visits in which health literacy skills training and clarification of the misunderstanding of drug labels, appointment sheets and use of common drugs will be made via a comic book. Measures include medication knowledge and compliance scale (MKCS) and Chinese Health Literacy Scale for Chronic Care (CHLCC).
Significance of the study: This study provides evidence of the use of comic books in medication compliance and health literacy.
Collaboration Proposal for Pain and Related Situations among Frail Older Adults in Yan Chai Hospital: a Cross-sectional Study
Investigators Name:
PI: Dr Mun Yee Mimi TSE
Co-I: Mr Yiu Cho KWAN
Funding Scheme/ Source of Funding: Yan Chai Hospital
Total Grant: HK $120,000
Commencement Date: 24-Aug-16
Background: Aging is a worldwide issue. Higher prevalence of pain and frailty are found in ageing population while pain and frailty may negatively influence the psychosocial well-being of older adults. However, few studies explore the association between pain, frailty and psychosocial well-being of older adults in Hong Kong.
Aim and objective: To investigate pain and pain-related situations among frail older adults, and to explore the relationship between pain, frailty and psychosocial well-being among older adults.
Design: Cross-sectional study.
Setting: Hospital and Geriatric Day Rehabilitation Center.
Sample: 360 participants will be recruited based on convenience sampling.
Measurements: Abbreviated Mental Test 10 will be used to assess the cognitive status of participants for screening. The pain situation and psychosocial well-being will be measured by Brief Pain Inventory - Chinese version and The World Health Organization Quality ofLife-BREF (WHOQOL-BREF) for cognitive intact participants while Abbey Pain Scale and The Quality of Life-Alzheimer's Disease (QOL-AD) are for cognitive impaired participants or those who cannot verbalize. A questionnaire about demographic data and pain-related situations, Fried Frailty Index and FRAIL scale for measuring frailty, and Subjective Happiness Scale - Chinese version for measuring psychological well-being will be adopted for all participants.
Data analysis: Kruskal-Wallis ANOVA will be used to test the differences in pain sitnations of participants who arc divided into three groups of frailty, robust, pre-frail and frail. Linear correlation will be analysed using Chi-square for QOL-AD and pain, and Pearson test for WHOQOL-BREF and pain. To compare the psychosocial well-being of three groups of frailty, ANOVA will be used for Snbjeetive Happiness Scale, Chi-square for QOL-AD, and Kruskal-Wallis ANOVA for WHOQOL-BREF.
Expected outcome: Positive association between pain and frailty, negative associations between pain and psychosocial well-being, and between frailty and psychosocial well-being of older adults are expected. Significance of study: The findings will lay the foundation for designing more effective rehabilitation programme for older adults in Hong Kong.
Changing The Way We Prevent Diabetes: The Use of Mobile Application
Investigators Name:
PI: Dr Yee Man Angela LEUNG
Funding Scheme/ Source of Funding: Health Care and Promotion Fund
Total Grant: HK $281,720
Commencement Date: 15-Apr-16
Background: Mobile application has been proven to be a valuable method to increase adults’ health awareness.
Aim: This project aims to promote diabetes risk self-assessment and lifestyle modification with the use of electronic devices.
Design: A longitudinal design with a 3-month intervention for the high-risk persons of diabetes.
Subjects: A total of 2,500 persons aged 40 to 70 will be approached and invited to use the HKU Diabetes Risk Score (HKU DRS) app. Among these, 300 high-risk persons will be invited to join the 3-month phone intervention. Mobile applications will be used to record participants’ lifestyle. Graphs shown in the app (such as diabetes risk level, energy consumption per day) and health advices in the app and phone calls will serve as facilitators to lifestyle change.
Significance: This project contributes to empower individuals to change lifestyle with the support of electronic technology and reduce the chance the progression to diabetes.
A Study to Review Clinical Practice Issues of the Aged Homes of the Yuen Yuen Institute to Enhance Quality Residential Care
Investigators Name:
PI: Prof. Kam Yuk LAI
Co-I: Dr Wai Yung KWONG, Dr Yat Wa Justina LIU, Mr Pui Kin KOR, Mr Yiu Cho KWAN, Ms Lai Ping LEE
Funding Scheme/ Source of Funding: The Yuen Yuen Institute Social Service Department
Total Grant: HK $496,447
Commencement Date: 15-May-15
Background: In the specifications in the Call for Tender, the Social Service Department of the Yuen Yuen Institute (YYI) indicated three main practice issues that were to be examined. Consequently, this study focus on these three special aspects of long-term residential care, namely falls and fall prevention, restraint reduction, and infection control practice review.
The objectives of this study included: (i) To review the YYI’S existing practices in the YYH and YYC&A in the following three aspects of care: (a) Prevention of falls (b) Restraint policy (Least Restraint Policy), and (c) Infection control practices (ii) To propose recommendations for the standardization of existing policies for the two subvented homes.
Healthy Living Programme (HLP): Diet, Drug and Fall Prevention for Community-dwelling Frail Older Adults
Investigators Name:
PI: Dr Mun Yee Mimi TSE
Co-I: Ms Sin Man HEUNG
Funding Scheme/ Source of Funding: Pentecostal Church of Hong Kong
Total Grant: HK $150,000
Commencement Date: 15-Dec-14
The Effect of Horticultural Therapy (HT) for Frail Older People in Residential Care
Investigators Name:
PI: Prof. Kam Yuk LAI
Co-I: Dr Mun Yee Mimi TSE, Mr Jordan LAU, Mr Yiu Cho KWAN, Ms Ka Lai Shirley LO
Funding Scheme/ Source of Funding: Pok Oi Hospital
Total Grant: HK $376,908
Commencement Date: 1-Jul-14
A Project of Music Intervention for People with Dementia and Their Family Caregivers
Investigators Name:
PI: Prof. Kam Yuk LAI
Co-I: Dr Daphne S.K. CHEUNG, Dr Jacqueline HO
Funding Scheme/ Source of Funding: Ho Cheung Shuk Yuen Charitable Foundation
Total Grant: HK $1,093,455
Commencement Date: 15-May-14
Counseling Service and Research Study in End of Life Care and Advance Care Planning
Investigators Name:
PI: Dr Wai Yung KWONG
Co-I: Dr Tak Yin LAU, Prof. Mei Che PANG
Funding Scheme/ Source of Funding: Haven of Hope Christian Service
Total Grant: HK $312,000
Commencement Date: 10-Apr-14
The study aims to examine the effectiveness of implementing advance care in caregivers. 25 patients were recruited to answer quality of life and patient satisfaction questionnaire, while 14 caregivers were recruited to answer quality of care and quality of death questionnaire. Collected data was analyzed both in quantitative and qualitative way. Result showed no statistical significant effect on psychological and physical improvement of patients and caregivers across three prognostic windows (days, weeks, months). However, the case-based analysis could reveal the gradual improvement of patients and caregivers in various aspects, thus brought out the importance of advance care planning implementation to end of life care.
PRACTICE IMPLICATION: Eight workshops were conducted for staffs training nursing students learning. Advance care planning was introduced through presenting research finding, discussing cases, and practicing the use of instruments. One evidence-based practice guideline was also completed for staffs to facilitate the initiation of sensitive conversations in the future work.
Implementation of Observational Pain Management Protocol to Improve Pain Management for Long-term Institutionalized Older Care Home Residents with Dementia: A Randomized Controlled Trial
Investigators Name:
PI: Dr Yat Wa Justina LIU
Funding Scheme/ Source of Funding: RGC Early Career Scheme
Total Grant: HK $669,000
Commencement Date: 1-Jan-14
An Exploratory Study on the Effect of Horticultural Therapy for Mentally Handicapped Adults
Investigators Name:
PI: Prof. Kam Yuk LAI
Co-I: Dr Yim Wah MAK, Mr Yiu Cho KWAN, Ms Connie FUNG
Funding Scheme/ Source of Funding: Hong Kong Association of Therapeutic Horticulture Limited
Total Grant: HK $50,000
Commencement Date: 1-Jul-13
The Spending Habits of Silver Market Population
Investigators Name:
PI: Dr Mun Yee Mimi TSE
Co-I: Dr Wing Cheung Eric TAM
Funding Scheme/ Source of Funding: Senior Citizen Home Safety Association
Total Grant: HK $385,200
Commencement Date: 15-Jun-13
Standardization of an Acupressure Protocol for Managing Agitation in Nursing Home Residents with Dementia: A Pilot Study
Investigators Name:
PI: Mr Yiu Cho KWAN
Co-I: Prof. Kam Yuk LAI
Funding Scheme/ Source of Funding: Sigma Theta Tau International
Total Grant: HK $38,031
Commencement Date: 1-May-13
Subject population: The agitated nursing home residents with dementia.
Research design: Quasi-experimental: time series design with multiple groups. Instruments: Cohen-Mansfield Agitation Inventory (CMAI) for agitation, enzyme-link immunosorbent assay (ELIZA) for salivary cortisol (as a marker of stress).
Procedure: 24 participants will be sampled from the target population by convenience sampling. Samples will be evenly assigned into eight groups which consist of two dosage factors of the intervention (ie. frequency and duration). Subjects in each group will receive acupressure at various dosages as specified by the study group. For example, in group G1-2, the subject will receive the acupressure once a day for two week. The outcomes (ie. agitation and stress) will be measured repeatedly over time (maximally eight weeks) at a fixed interval until the stability of the outcomes resume, which indicates that the acupressure effect is weaned off. For the agitation, it will be measured by CMAI weekly from the commencement day of the acupressure until the agitation level resumes stability after the completion of the acupressure. For the stress, it will be measured by salivary cortisol every three days. The measurement will start 6 days before the commencement day of acupressure until the salivary cortisol level resumes stability after the completion of the acupressure.
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