A Novel Drug helps Suppressing Tumor Growth
A novel and natural-source based synthetic drug (83b1) was shown to suppress tumor growth via targeting an oncoprotein PPARδ which produces the carcinogenic products COX-2 and PGE2.
83b1 with novel composition can target on a known cancer oncoprotein with no exiting drugs which were intended to do the same. Moreover, the existing data showed low toxicity on non-tumor cells and normal mice which offers a very good opportunity with high potential to be developed as a new anti-cancer agent.
The invention has been recently granted with US and China patents which were licensed to a drug company with the continuous search for sublicensees. Moreover, the potential action of 83b1 to suppress PGE2 production will also offer another opportunity to explore it as a novel antiinflammatory agent.