日期：2017 年 06 月 21 日 ( 星期三)
Time：11:00 am – 12:00 pm
A new concept, bio-functionalization of metallic biomaterials, is proposed for future development of metallic biomaterials that are generally applied for medical devices by using their load-bearing abilities. This creative idea can be realized through continuous release of a specially alloyed biofunctional metal element from surfaces of the alloy in body environment, which has been well verified to be possible by both in vitro and in vivo experimental evidences on the newly developed Cu-bearing metals as well as biodegradable magnesium based metals, indicating that a trace amount of Cu released from the Cu-bearing metals could have obvious bio-functions of antimicrobials, reduction of in-stent restenosis (ISR), and even promoting early osteogenesis, and that degradation of magnesium based metals in body environment could promote new bone formation, and even have strong antibacterial ability and reduce survival of bone tumor cells due to the local enhancement of both pH and Mg ions concentration. Satisfied load-bearing ability with special biofunction for a metallic biomaterial will bring higher application values for metal implants. This is an attractive direction for research and development with many challenges, and the final target will be much beneficial to the majority of patients.
Prof. Yang is the Division Head and Professor of Specialized Materials and Devices at the Institute of Metal Research (IMR) of Chinese Academy of Science (CAS). He received his MS and PhD degree at IMR, CAS in 1985 and1989, respectively. Prof. Yang is the Chair of Metallic Biomaterials Branch, Chinese Biomaterials Association, leading the largest team on novel metallic biomaterials research and applications in China. He is a Fellow of Biomaterials Science & Engineering (FBSE), International Union of Societies for Biomaterials Science & Engineering. He is also visiting professors of China University of Science & Technology, Northeast University, Nanjing University of Technology, and China Medical University.