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2014 年 04 月 22 日
Seminar - MEMS and Microfluidics Research at HKUST by Dr. Yi-Kuen Lee
Date: 22 April 2014 (Tuesday)
 
Time: 11:00 am – 12:00 pm
 
Venue:EF305, The Hong Kong Polytechnic University
Abstract:
 
MEMS and Microfluidics have been rapidly developing in new frontiers of medical diagnostics, optofluidics, nanofluidics and agribiotechnology. In the past decades, the applications of these devices gradually change from conventional sensor applications to biohazard detection systems, in-vitro medical diagnostics systems & implantable medical devices for hospital and home care and pharmaceutical industry. In this presentation, we will also discuss several representative and unique MEMS and microfluidic devices developed at HKUST including micro chaotic mixers and their application in early cancer diagnostics, Giant Electrorheological Fluid-based microfluidics, micro electroporation & micro electroendocytosis chips, the discovery and screening of traditional Chinese medicine using closed-loop feedback control and micro thermal heat transfer and flow sensors. In addition, we also developed the corresponding theoretical and numerical modeling and simulations (Biased Reptation Model with Electrosmosis for Micro/nanoelectrophoresis of large DNA molecules, hyperelastic electromechanical continuum model for single-cell electroporation) to facilitate the optimization of devices’ design and performance.
 
Bio-sketch:
 
Dr. Yi-Kuen Lee received his BS degree in Bio-Industrial Mechatronics Engineering Department, National Taiwan University (NTU) in 1992. He received his MS degree in the Institute of Applied Mechanics, NTU in 1995. After finishing two-year military service, he went to US and obtained Ph.D. degree in Mechanical Engineering with Major in MEMS (joint program between ME and EE at UCLA) under the guidance of Prof Chih-Ming Ho (member of Academia Sinica and US NAE) at UCLA in 2001. He was an Assistant Professor from 2001 to 2007 at HKUST. He received substantiation and was promoted to Associate Professor in 2007. He was a Visiting Associate at Caltech in 2011. He has published two book chapters, 42 refereed journal papers and 76 refereed international conference papers. His current research topics include microfluidics for enumeration of Circulation Tumor Cells (CTCs) for cancer diagnostics, microchips for DNA transfection, micro/nano heat transfer, micro/nano electrophoresis for large DNA molecules, MEMS sensors for environmental monitoring and energy-efficiency building. He was the co-founder of the annual Nano/Micro Engineered and Molecular Systems (IEEE NEMS) conferences since 2006; Technical Program Committee (TPC) member of IEEE MEMS 2007, Kobe, Japan; TPC member of IEEE Nano 2007; TPC member of APCOT 2008, 2010 & 2012, TPC member of IEEE NEMS 2009, 2010, 2011 & 2012, IEEE Transducers 2009 & 2011. He is also the Chair for the 5th International Workshop on Innovation and Commercialization of Micro & Nano Technologies (ICMAN 2011), Shenzhen, 5-8 Nov 2011. He is the President of Hong Kong Society of Theoretical and Applied Mechanics since March 2014.

Date: 22 April 2014 (Tuesday)

Time: 11:00 am – 12:00 pm

Venue:EF305, The Hong Kong Polytechnic University

Abstract:

MEMS and Microfluidics have been rapidly developing in new frontiers of medical diagnostics, optofluidics, nanofluidics and agribiotechnology. In the past decades, the applications of these devices gradually change from conventional sensor applications to biohazard detection systems, in-vitro medical diagnostics systems & implantable medical devices for hospital and home care and pharmaceutical industry. In this presentation, we will also discuss several representative and unique MEMS and microfluidic devices developed at HKUST including micro chaotic mixers and their application in early cancer diagnostics, Giant Electrorheological Fluid-based microfluidics, micro electroporation & micro electroendocytosis chips, the discovery and screening of traditional Chinese medicine using closed-loop feedback control and micro thermal heat transfer and flow sensors. In addition, we also developed the corresponding theoretical and numerical modeling and simulations (Biased Reptation Model with Electrosmosis for Micro/nanoelectrophoresis of large DNA molecules, hyperelastic electromechanical continuum model for single-cell electroporation) to facilitate the optimization of devices’ design and performance.

Bio-sketch:

Dr. Yi-Kuen Lee received his BS degree in Bio-Industrial Mechatronics Engineering Department, National Taiwan University (NTU) in 1992. He received his MS degree in the Institute of Applied Mechanics, NTU in 1995. After finishing two-year military service, he went to US and obtained Ph.D. degree in Mechanical Engineering with Major in MEMS (joint program between ME and EE at UCLA) under the guidance of Prof Chih-Ming Ho (member of Academia Sinica and US NAE) at UCLA in 2001. He was an Assistant Professor from 2001 to 2007 at HKUST. He received substantiation and was promoted to Associate Professor in 2007. He was a Visiting Associate at Caltech in 2011. He has published two book chapters, 42 refereed journal papers and 76 refereed international conference papers. His current research topics include microfluidics for enumeration of Circulation Tumor Cells (CTCs) for cancer diagnostics, microchips for DNA transfection, micro/nano heat transfer, micro/nano electrophoresis for large DNA molecules, MEMS sensors for environmental monitoring and energy-efficiency building. He was the co-founder of the annual Nano/Micro Engineered and Molecular Systems (IEEE NEMS) conferences since 2006; Technical Program Committee (TPC) member of IEEE MEMS 2007, Kobe, Japan; TPC member of IEEE Nano 2007; TPC member of APCOT 2008, 2010 & 2012, TPC member of IEEE NEMS 2009, 2010, 2011 & 2012, IEEE Transducers 2009 & 2011. He is also the Chair for the 5th International Workshop on Innovation and Commercialization of Micro & Nano Technologies (ICMAN 2011), Shenzhen, 5-8 Nov 2011. He is the President of Hong Kong Society of Theoretical and Applied Mechanics since March 2014.