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Cancer

Subject Coordinators:

Prof. Jing CAI

Prof. Michael YING

Prof. Shea-ping YIP

 

Sub-thematic areas:

Molecular mechanisms of cancer for diagnosis and treatment

Dr Marco TAM

Email: marco-shing-yau.tam @polyu.edu.hk

 

Targeting signaling pathways in tumor microenvironment for cancer treatment

Dr Alvin MA

Email: alvin.ma@polyu.edu.hk

 

1. Molecular mechanism of leukemogenesis

2. Developing zebrafish model of human leukemia

3. High throughput durg screening for novel target therapuetic agents of luekemia

Prof. Benjamin YUNG

Email: ben.yung@polyu.edu.hk

 

 

Dr Chien-ling HUANG

Email: cl.huang@polyu.edu.hk

 

(1) Role of Long Non-coding RNAs in Myeloproliferative Neoplasms and Myeloid Malignancies (2) Mechanisms in Regulating Drug Resistance of Chronic Myeloid Leukaemia

Dr Helen LAW

Email: helen.law@polyu.edu.hk

 

Carcinogensis and radiosensitivity of colorectal cancer

The role of autophagy

Dr Lawrence CHAN

Email: wing.chi.chan@polyu.edu.hk

 

Bioinformatics, role of microRNAs in cancer.

Dr Liang-ting LIN

Email: lt.lin@polyu.edu.hk

 

Cancer signaling cascade responding to radiation therapy; non-coding RNA (lncRNA and miRNA) regulation in cancer therapy; microenvironmental changes in photothermal therapy.

Prof. Shea-ping YIP

Email: shea.ping.yip@polyu.edu.hk

 

 

 

 

 

Discovery of biomarkers for cancer diagnosis

Dr Helen LAW

Email: helen.law@polyu.edu.hk

 

Molecular and epigenetic markers related to carcinogenesis and autophagy

Prof. Benjamin YUNG

Email: ben.yung@polyu.edu.hk

 

 

Dr Cesar WONG

Email: cesar.wong@polyu.edu.hk

 

To develop novel panel of biomarkers for disease detection, monitoring and therapeutic drug response.

 

 

Immune regulation of cancer progression and therapy

Dr Marco TAM

Email: marco-shing-yau.tam @polyu.edu.hk

 

Immune evasion of colorectal cancer

Dr Chien-ling HUANG

Email: cl.huang@polyu.edu.hk

 

JAK2-PDL1 Axis in Immune Regulation of Myeloproliferative Neoplasms

 

 

Development of imaging techniques for cancer diagnosis

Dr Helen LAW

Email: helen.law@polyu.edu.hk

 

Ultrasound, Computed Tomography, Magnetic Resonance Imaging and Nuclear medicine for cancer diagnosis

Dr Jung Sun YOO

Email: jungsun.yoo@polyu.edu.hk

 

Dr.Yoo's group focuses on development of in vivo imaging techniques using the power of light to revolutionize clinical practice in cancer diagnosis. We are interested in development of novel fluorescence molecular imaging technologies and multimodal imaging strategies for intraoperative guidance, diagnosis, and prognostication of cancer. Current projects include development of spectral reflectance imaging system to visualize peripheral nerves during cancer surgry and single cell resolution pharmacokinetic and pharmacodynamic imaging of nanomedicine to treat cancer.

Dr Lawrence CHAN

Email: wing.chi.chan@polyu.edu.hk

 

AI application in cancer imaging, radiomics.

Prof. Michael YING

Email: michael.ying@polyu.edu.hk

 

Ultrasound diagnosis of head and neck cancers and their associated metastases; Computer-aided diagnosis of cancers

 

 

Development of cancer treatment approaches

Dr Marco TAM

Email: marco-shing-yau.tam @polyu.edu.hk

 

Development of individualized radiotherapy and biological target; Development of novel treatment approaches against metastasis

Prof. Jing CAI

Email: jing.cai@polyu.edu.hk

 

Image-guided radiation therapy, MRI-guided radiation therapy, 4D imaging techniques, artifitial intelligence applications in radiation therapy, functional imaging, novel treatment techniques

Dr Liang-ting LIN

Email: lt.lin@polyu.edu.hk

 

Photoacoustic imaging-guided photothermal therapy; Image-guided nanoparticle treatments; radiosensitizing agents

 

Radiation Dosimetry and Protection

Dr Marco TAM

Email: marco-shing-yau.tam @polyu.edu.hk

 

Dosimetric evaluation of rectal cancer radiotherapy techniques, Natural and artificial radiation protection

Prof. Jing CAI

Email: jing.cai@polyu.edu.hk

 

Functional avoidance radiation therapy, smart wearble devices for radiation dosiemtry and protection

 

Monitoring and predicting cancer treatment outcomes

Dr Marco TAM

Email: marco-shing-yau.tam @polyu.edu.hk

 

Monitoring of tumor microenvironment for predicting cancer treatment outcomes

Dr Alvin MA

Email: alvin.ma@polyu.edu.hk

 

The use of autophagy in leukemia diagnosis and prognosis

Prof. Benjamin YUNG

Email: ben.yung@polyu.edu.hk

 

 

Dr Chien-ling HUANG

Email: cl.huang@polyu.edu.hk

 

Novel Molecular Assay for Monitoring Minimal Residual Disease in Chronic Myeloid Leukaemia

Dr Cesar WONG

Email: cesar.wong@polyu.edu.hk

 

To develop Big Data in disease re-classification and risk prediction

To study novel anti-cancer drug response using mouse models

Dr Helen LAW

Email: helen.law@polyu.edu.hk

 

Molecular and epigenetic markers related to carcinogenesis and autophagy

Prof. Jing CAI

Email: jing.cai@polyu.edu.hk

 

Radiomics, radiation therapy resposne assessment and prediction

 

Dr Lawrence CHAN

Email: wing.chi.chan@polyu.edu.hk

 

Responsiveness of cancer treatment

Dr Liang-ting LIN

Email: lt.lin@polyu.edu.hk

 

Molecular imaging - protein-protein interaction, nanoparticle and exosome tracking, bio-distribution and pharmacokinetics; exosome constitution analysis for cancer prognosis.

Prof. Michael YING

Email: michael.ying@polyu.edu.hk

 

Ultrasound monitoring of treatment responses; Ultrasound assessment of post-radiotherapy complications; Computer-aided assessment

Dr Shara Lee

Email: shara.lee@polyu.edu.hk

 

Prof. Shea-ping YIP

Email: shea.ping.yip@polyu.edu.hk

 

 

Management of cancer treatment side-effects

Dr Marco TAM

Email: marco-shing-yau.tam @polyu.edu.hk

 

Management of rectal cancer radiotherapy side effects

Dr Shara Lee

Email: shara.lee@polyu.edu.hk

 

Use of photobiomodulation (BPM)/low-level laser therapy for the management of radiation-induced dermatitis and oral mucositis.