DEPARTMENT OF APPLIED BIOLOGY & CHEMICAL TECHNOLOGY 46 Email cong.ma@polyu.edu.hk Qualification BSc (China Pharmaceutical University) PhD (Ecole Polytechnique) Postdoc (Massachusetts Institute of Technology) ORCID ID 0000-0001-9245-0356 Dr MA Cong Associate Professor Research Overview AI-assisted drug design We are using cutting-edge AI technology to design small molecules and peptides for drug discovery research Drug discovery & development We are focusing on protein-protein interactions to discover new antimicrobial, antiviral and anticancer drug candidates with minimized drug resistance for further development Organic chemistry methodology We are interested in developing novel methods to synthesize pharmaceutically important structures using commodity chemicals under environmentally friendly conditions. These methods can be very useful for the chemical and pharmaceutical industry Representative Publications • Int. J. Mol. Sci. 2023, 24, 339 • Bioorg. Chem. 2022, 124, 105863 • Org. Lett. 2021, 23, 6164-6168 • J. Med. Chem. 2020, 63, 7695-7720 • Bioorg. Chem. 2019, 92, 103203 • Eur. J. Med. Chem. 2019, 178, 214-231 • Biochemistry 2017, 56, 5049-5052 Patents • N-Substituted oseltamivir derivatives with antimicrobial activity (WO2020259471A1, CN114286817A, US20220306592A1) • Compounds with antimicrobial activity (WO2020001321A1, CN112638909A, US20220388953A1) • Compounds with antimicrobial activity (WO2019138323A1, CN111971271A, EP3737664A1, US20200347010A1, JP2021510143A) Awards and Achievements • Global Innovation Award, TechConnect World Innovation Conference & Expo., 2019 • Honorary Key Technology Partner Visiting Fellow, University of Technology Sydney, 2019 • Faculty Early Career Research Award, University of Newcastle, 2015 • International Postdoctoral Research Fellowship, L’X & MIT, 2009 • EGIDE Postgraduate Research Fellowship, French Ministry of Foreign Affairs, 2005
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