DEPARTMENT OF APPLIED BIOLOGY & CHEMICAL TECHNOLOGY 44 Email xiuyuan.li@polyu.edu.hk Qualification BSc (Massachusetts Institute of Technology) PhD (Stanford University) ORCID ID 0000-0002-3970-8183 Dr LI Xiuyuan Ted Assistant Professor Presidential Young Scholar Research Overview Our research focuses on the development of strategies to visualize and modulate neural activities. We aim to: (1) develop probes to record activity history of neurons in live animals that can be later read to provide brain-wide information (2) design small-molecule-, protein-, and nucleic acid-based tools to modulate brain states with high spatial and temporal resolution Patent • “Use of Intercellular Protein Fibers to Record Cellular Events”, Cohen AE, Lin D, Li X and Kim D, pending approval, 2023 Representative Publications • Nat. Biotechnol., 2023, 41, 631 • Science, 2021, 374, 729 • J. Am. Chem. Soc., 2020, 142, 14933 • Biochemistry, 2018, 57, 6201 • J. Am. Chem. Soc., 2018, 140, 6518 • ACS Cent. Sci. 2016, 2, 14 • Chembiochem., 2014, 15, 713 • J. Am. Chem. Soc., 2010, 132, 8774
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