Research at FAST

43 Representative Publications • Jiang L , Lung HL, Huang T, Lan R, Zha S, Chan LS, Thor W, Tsoi TH, Chau HF, Boreström C, Cobb SL, Tsao SW, Bian ZX, Law GL, Wong WT, Tai WCS, Chau WY, Du Y, Tang LHX, Chiang AKS, Middeldorp JM, Mak NK, Long NJ, Wong KL. Reactivation of Epstein Barr virus by a dual-responsive fluorescent EBNA1-targeting agent with zinc-chelating function. PNAS 2019 ;116:26614-24 • Clough TJ # , Jiang L # , Wong KL, Long NJ. Ligand design strategies to increase stability of gadolinium-based MRI contrast agents. Nature Communications 2019 ;10:1420 • Boltersdorf T, Ansari J, Senchenkova EY, Jiang L , Coogan M, Gavins FNE, Long NL. Development, characterisation and in vitro evaluation of lanthanide- based FPR2/ALX-targeted imaging probes. Dalton Transactions 2019 ;48:16764-75 • Jiang L , Xie C, Lung HL, Lo KW, Law GL, Mak NK, Wong KL. EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers. Theranostics 2018 ;8:5307-5319 Dr JIANG Lijun Research Assistant Professor Research Areas Research interests include the design and development of responsive luminescent probes for specific biological targets and their underlying mechanism studies, as well as the ligand design strategies for stable gadolinium-based MRI contrast agents. Qualification MSc (Wuhan) PhD (HKBU) ORCID ID 0000-0002-6499-9760 • Jiang L , Lan R, Huang T, Chan CF, Li H, Lear S, Zong J, Wong WY, Lee MML, Chan BD, Chan WL, Lo WS, Mak NK, Lung ML, Lung HL, Tsao SW, Taylor GS, Bian ZX, Tai WCS, Law GL, Wong WT, Cobb SL, Wong KL. EBNA1- targeted probe for the imaging and growth inhibition of tumours associated with the Epstein-Barr virus. Nature Biomedical Engineering 2017 ;1:0042 • Jiang L , Lau LL, Li H, Chan CF, Lan R, Chan WL, Lau TCK, Tsao SW, Mak NK, Wong KL. EBNA1 specific lumines cence small molecules for imaging and inhibition of latently EBV-infected tumor cells. Chemical Communications 2014 ;50:6517-19 Patent • “Therapeutic inhibitor for EBV-associated tumor with tailor responsive optical imaging”. US Patent, US010137115 Department of Applied Biology & Chemical Technology Department of Applied Biology & Chemical Technology