The Role of Corneal Parameters During Myopia Development
The myopic (short-sighted) population has been increasing worldwide over recent decades, the global prevalence was projected to reach 50% in 2050 (Holden et al., 2016). Myopia can cause irreversible ocular damages that can lead to blindness, making myopia a public health concern that urges preventive measures. However, the mechanism of myopization is not fully understood, and therefore, both the prediction of myopia progression and the design of personalized treatments are difficult in clinical practice.
The cornea is the major refractive component of human eyes, accounting for nearly two-thirds of the total refractive power, this has made the cornea one of the potential factors influencing myopia progression. The cornea is also the site of action for orthokeratology, which is shown to be an effective myopia control regimen in randomized clinical trials. A comprehensive understanding of corneal geometry and optics is, hence, potentially beneficial to unravel the mechanism behind myopia progression, and to the optometric practice of myopia control.