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Dr Danyue Zhao Daisy
Open Platform for University Scholars

Dr Zhao Danyue, Daisy

Assistant Professor

Education and Academic Qualifications

  • PhD, The University of Hong Kong
  • Bachelor (Hons.), Hong Kong Baptist University
  • Postdoctoral Associate, Rutgers - The State University of New Jersey, New Brunswick

Professional Qualifications

  • Postdoctoral Associate, Rutgers - The State University of New Jersey, New Brunswick
  • PhD, The University of Hong Kong
  • Bachelor (Hons.), Hong Kong Baptist University

Research Overview

We are interested in studying the interactions between bioactive phytochemicals and gut microbiota, and the novel approaches to extend the bioefficacy of phytochemicals in disease prevention.

Academic and Professional Experiences

  • Member of The American Society for Nutrition
  • Member of The Metabolomics Society
  • Member of The Institute of Food Technologists (IFT) 
  • Member of The International Society for Nutraceuticals and Functional Foods

Research Interests

  • Polyphenols
  • Phytonutrients
  • Gut Microbiota
  • Probiotics
  • Metabolomics
  • Mass Spectrometry
  • Natural Product Chemistry
  • Precision Nutrition


  • ASN Postdoctoral Research Award, American Society for Nutrition, Nutrition 2019, Baltimore, MD, USA.
  • ASN Travel Award - Dietary Bioactive Component Research Interest Section, Nutrition 2019, Baltimore, MD, USA.
  • Metabolomics Society Early Career Travel Award for Metabolomics 2018, the 14th Annual International Conference of the Metabolomics Society, Seattle, WA, USA.
  • Li Po Chun Charitable Trust Fund Postgraduate Scholarship2015, Hong Kong Li Po Chun Charitable Trust Fund, Hong Kong.
  • FereidoonShahidi Fellowship Award 2015, The International Society for Nutraceuticals and Functional Foods, Wuxi, China.
  • Scholastic Award of The Year 2012, Hong Kong Baptist University, Hong Kong.
  1. Yuan, B., Zhao, D.*, Lyu W., Yin Z., Kshatriya, D., Bello, N.T., Simon, J.E., and Wu, Q.* Development and validation of a micro-QuEChERS method with high-throughput enhanced matrix removal followed with UHPLC-QqQ-MS/MS for analysis of raspberry ketone-related phenolic compounds in adipose tissues. Talanta (2021); 235; 122716. (*Corresponding author)
  2. Zhao, D.; Yuan, B.; Kshatriya, D.; Polyak, A.; Simon, J.E., Wu, Q.L. & Bello, N.T. (2020). Influence of diet-induced obesity on the bioavailability and metabolism of raspberry ketone (4-(4-hydroxyphenyl)-2-butanone) in mice. Molecular Nutrition and Food Research, 64, 1900907.
  3. Wang, J., Zhao, D., Tiano, S., Esteban-Fernández, A., Yuan, B., Smith, C., Brathwaite, J., Jlayer, Z., Wu, Q., Simon, J.E., Trageser, K.J., Pasinetti, G.M. (2020). Prophylactic effect of flavanol rich preparation metabolites in promoting resilience to a mouse model of social stress. Translational Psychiatry, 10, 183.
  4. Westfall, S., Caracci F., Zhao D., Wu, Q.L., Frolinger, T., Simon, J.E., Pasinetti, G.M. (2020). Microbiota metabolites modulate the T helper 17 to regulatory T cell (Th17/Treg) imbalance promot-ing resilience to stress-induced anxiety-and depressive-like behaviors. Brain, Behavior, and Immunity, in press (Available online 21 October 2020).
  5. Ho, L.(#1); Zhao, D.(#1); Ono, K.; Ruan, K.; Mogno, I.; Tsuji, M.; Carry, E.; Brathwaite, J.; Sims, S.; Frolinger, T.; Westfall, S.; Mazzola, P.; Simon, J.E.; Wu, Q.L.; Faith, J. & Pasinetti, G.M. (2019). Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity. The Journal of Nutritional Biochemistry, 64, 170-181.
  6. Zhao, D.; J.; Simon, J.E. & Wu, Q.L. (2019). A Critical Review on Grape Polyphenols for Neuroprotection: Strategies to Enhance Bioefficacy. Critical Reviews in Food Science and Nutrition, 4, 597-625.
  7. Carry, E.(#1); Zhao, D.(#1); Faith, J.; Ho, L.; Villani, T.; Patel, H.; Pasinetti, G.M.; Simon, J.E. & Wu, Q.L. (2018). Development and validation of a gas chromatography-triple quadruple mass spectrometry method for quantification of microbial phenolic acid metabolites derived from grape flavanols. Journal of Pharmaceutical and Biomedical Analysis, 159, 374-383.
  8. Zhao, D.; Yuan, B.; Carry, E.; Pasinetti, G.M.; Ho, L.; Faith, J.; Mogno, I.; Simon, J.E. & Wu, Q.L. (2018). Development and validation of an ultra-high performance liquid chromatography/triple quadrupole mass spectrometry method for analyzing microbial-derived grape polyphenol metabolites. Journal of Chromatography B, 1099, 34-45.
  9. Ou, J.; Huang, J.; Zhao, D.; Du, B.; Wang, M. (2018). Protective effect of rosmarinic acid and carnosic acid against streptozotocin-induced oxidation, glycation, inflammation and microbiota imbalance in diabetic rats. Food & Function, 9, 851-860.
  10. Zhao, D. & Shah, N.P. (2016). Synergistic administration of lactic acid bacteria and black tea enhances polyphenols bioavailability and relieves D-galactose induced oxidative stress in mice via modulating glutathione-related enzymes. The Journal of Nutritional Biochemistry, 38, 116 – 124.
  11. Zhao, D. & Shah, N.P. (2016). Synergistic application of black tea extracts and lactic acid bacteria in protecting human colonocytes against oxidative damage. Journal of Agricultural and Food Chemistry,64, 2238–2246.
  12. Zhao, D. & Shah, N.P. (2015). Tea and soybean extracts in combination with milk fermentation inhibit growth and enterocyte adherence of selected foodborne pathogens. Food Chemistry, 180, 306-316.

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