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Dr Chunyi Wen
Open Platform for University Scholars

Dr Chunyi Wen

Associate Professor

Exploits an east-meets-west approach for the discovery of anti-ageing formula

Biography

Dr. Wen obtained his Bachelor’s degree in Medicine and Surgery from West China School of Medicine and practiced in West China Hospital, a top-ranked hospital in China. Later, he completed his postgraduate training in the Department of Orthopaedics and Traumatology of The University of Hong Kong and The Chinese University of Hong Kong, and received Master of Medical Science and Doctor of Philosophy degrees, respectively. Under the auspices of China Medical Board and Health and Medical Research Fund, Dr. Wen received further training in Department of Orthopaedic Surgery at Johns Hopkins University in U.S.A, and Kennedy Institute of Rheumatology, University of Oxford.

In his early research career, Dr. Wen focused on the molecular mechanism and clinical implications of the age-related skeletal disorders such as osteoarthritis and osteoporosis. He, for the first time, discovered endothelin-1, a known vasoconstrictor, in the pathogenesis of subchondral bone disturbance and osteoarthritis. This work lays a solid foundation for vascular etiology of OA, and opens a new avenue for OA prevention and treatment. After joining PolyU BME, Dr. Wen connects orthopedic surgeons with biomedical engineers to develop a novel artificial intelligence-based precision medicine approach in a unique southern Chinese knee osteoarthritis patients cohort. With a newly established smart ageing hub in PolyU BME, Dr. Wen dreams to extend his work from hospital, clinic setting to the community service.

Research Interests

  • Cellular Senescence and Skeletal Aging
  • Precision Medicine for Skeletal Ageing
  • Data-driven Community-based Bone and Joint Healthcare Revolution

Academic and Professional Experiences

  • Assistant Professors, Department of Biomedical Engineering, Hong Kong Polytechnic University, Sep 2016 – current
  • Research Assistant Professor, Interdisciplinary Division of Biomedical Engineering, Hong Kong Polytechnic University, Jun 2015 – Sep 2016
  • Visiting scientist, Department of Orthopaedic surgery, School of Medicine, Johns Hopkins University, Baltimore, United States of American, Aug 2011 – Jan 2012
  • Honorary Assistant Professor, Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Mar 2010 – Mar 2017
  • Postdoctoral Fellow, Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Nov 2009 – Jun 2015
  • Doctor of Philosophy, Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Aug 2004 – Jan 2009
  • Master of Medical Science (Orthopedic Surgery), Faculty of Medicine, The University of Hong Kong, Aug 2003 – Jul 2004
  • Resident trainee in the Western China Hospital, affiliated hospital of West China School of Medicine, China (Top Ten Hospital in China, 2012~2013), Aug 2002 – Jul 2003
  • MB.BS, West China School of Medicine, Sichuan University, China, Aug 1997 – Jul 2002
  • Medical License issued by the Ministry of Health of People’s Republic of China

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