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Professor
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Shea-ping YIP
PhD (University College London) 1997
Human Genetics
MPhil (Hong Kong Polytechnic) 1992 Immunogenetics
FIBMS (by examination; specialist subject Haematology) 1988
HC(MLT) (HKU) 1985 Medical Laboratory Technology
ODip (Hong Kong Polytechnic) 1980 Medical Laboratory Science
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Brief Outline of Experience and Posts Held |
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2005 - |
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Professor, Department of Health Technology and Informatics, PolyU |
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Feb 2000 - 2005 |
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Associate Professor, Biomedical Science Section, School of
Nursing, PolyU |
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Oct 1992 - Jan 2000 |
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Assistant Professor/Lecturer (College of Degree
Studies), Biomedical Science Section, Department of Nursing & Health
Sciences, PolyU |
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Oct 1990 - Sept 1992 |
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Lecturer, Department of Health Sciences, Hong Kong Polytechnic |
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July 1987 - Nov 1990 |
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Medical Technologist, United Christian Hospital, Hong Kong |
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Jan 1987 - July 1987 |
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Acting Medical Technologist, United Christian Hospital, Hong
Kong |
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Sept 1980 - Jan 1987 |
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Medical Laboratory Technician II, United Christian Hospital,
Hong Hong |
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| Research Interests |
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Genetic variation: its detection, application and significance
in relation to human health-related conditions. Genetic analysis of complex
diseases, pharmacogenomics and molecular diagnostics |
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Service to Professional & Scientific Bodies, Consultancies
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External examiners of research postgraduate degrees
(1 PhD & 3 MPhil) |
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Reviewer for journals (Blood, British Journal
of Haematology, BMC Genetics, Clinical Chemistry, Journal of Biomedicine
and Biotechnology, Journal of Medical Genetics, Molecular Biology and Evolution
and Vox Sanguinis,) |
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Chairman, Examination Syllabus Subcommittee, Examination
Committee of Medical Laboratory Technologists Board, HK (Jun 2006 - Jun
2006) |
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Member, Credential and Training Subcommittee,
Registration Committee of Medical Laboratory Technologisits Board, HK (Jun
2006 - Jun 2006) |
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Founding Council Member & Academic Secretary,
Hong Kong Society of Molecular Diagnostic Sciences Ltd (2003 - present) |
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Member, Scientific Subcommittee, Ninth International
Conference on Myopia held on 10-14 Nov 2002 in Hong Kong/Guangzhou. |
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Member, Organizing Committee, Joint Symposium
on Frontiers of Medical Genetics Research, jointly hosted by the Hong Kong
Medical Genetics Society and Department of Nursing and Health Sciences (PolyU),
8 Sept 2001, Hong Kong. |
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Member, Scientific and Medical Advisory Committee,
Retina Hong Kong (Nov 1999-present) |
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Member, Organizing Committee, the Second Hong
Kong Medical Genetics Conference, 15-17 Oct 1999, Hong Kong. |
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Member, Scientific Subcommittee under the Organizing
Committee for the 21st World Congress of Medical Technology (Sept 1992 -
July 1994) |
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Deputy Panel Head, Haematology & Serology
Specialty in the Hong Kong Medical Technology Association Quality Assurance
Program (1991-Sept 94); Member (Sept 95 - Sept 96 & Nov 97 - present) |
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Member, Panel of Examiners in Haematology, Examination
Committee, Medical Laboratory Technologists Board, Supplementary Medical
Professions Council (1990-present). |
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| Awards and Patents |
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Commonwealth Academic Staff Scholarship (Sept
1994 to Sep 1997)
This was awarded by the Commonwealth Scholarship Commission in the United
Kingdom for full-time PhD studies in Human Genetics at the University College
London, University of London, UK
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Representative Publications (Journal Articles, Book Chapters, Monographs and Conference Papers; Total: 95)
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Yip SP, Choi PS, El-Zawahri MM, Luqmani Y. ABO
blood group in Kuwaitis: detailed allele frequency distribution and identification
of novel alleles. Transfusion 2005 (re-submitted |
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Jim JJT, Noponen-Hietala N, Cheung KMC, Ott J,
Karppinen J, Sahraravand A, Luk KDK, Yip SP, Sham PC, Song YQ, Leung JCY,
Cheah KSE, Ala-Kokko L, Chan D. The trp2 allele of collagen IX is an age-dependent
risk factor for the development and severity of intervertebral disc degeneration.
Spine 2005 (in press). |
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Yip SP, Fung LF, Lo STH. Rapid detection of Southeast Asian
-thalassaemia mutations by non-isotopic multiplex PCR-SSCP. Genet Test 2004;
8: 104-108. |
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Han W, Yip SP, Wan J, Yap MKH. Using denaturing
HPLC for SNP discovery and genotyping, and establishing the linkage disequilibrium
pattern for the all-trans-retinol dehydrogenase (RDH8) gene. J Hum Genet
2004;49:16-23. |
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Yip SP, Pun SF, Leung KH, Lee SY. Rapid simultaneous genotyping
of five common Southeast Asian -thalassemia mutations by multiplex minisequencing
and denaturaing HPLC. Clin Chem 2003; 49: 1656-1659 |
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Yip SP, Leung KH, Lin CK. Extent and distribution
of linkage disequilibrium around the SLC11A1 locus. Genes Immun 2003; 4:
212-221 |
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Yip SP, Lee SY, To SST, Wong ML. An improved real-time
PCR assay for homogeneous multiplex genotyping of four CYP2C9 alleles with
hybridization probes. Clin Chem 2003; 49: 2109-2111 |
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Yip SP, Chee KY, Chan PY, Chow EYD, Wong HF. Molecular genetic
analysis of para-Bombay phenotypes in Chinese: a novel non-functional FUT1
allele is identified. Vox Sang 2002; 83: 258-262 |
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Yip SP. Sequence variation at the human ABO locus. Ann Hum
Genet 2002; 66: 1-27. |
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Yip SP. Single-tube multiplex PCR-SSCP analysis distinguishes
seven common ABO alleles and readily identifies new alleles. Blood 2000;
95: 1487-1492 |
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Yip SP, Lovegrove JU, Rana NA Hopkinson DA, Whitehouse DB.
Mapping recombination hotspots in human phosphoglucomutase (PGM1). Hum Mol
Genet 1999; 8: 1699-1706 |
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Yip SP, Putt W, Hopkinson DA, Whitehouse DB. Identification
and characterization of polymorphisms in human phosphoglucomutase (PGM1).
Ann Hum Genet 1999; 63: 129-140 |
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Yip SP, Hopkinson DA, Whitehouse DB. Improvement of SSCP analysis
by use of denaturants. BioTechniques 1999; 27: 20-24 |
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Yip SP, Choy WL, Chan CW, Choi CH. The absence of a B allele
in acquired B blood group phenotype confirmed by a DNA based genotyping
method. J Clin Pathol 1996; 49: 180-181 |
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