Professor
Shea-ping YIP photo
Shea-ping YIP

  • PhD (University College London) 1997 Human Genetics
  • MPhil (Hong Kong Polytechnic) 1992 Immunogenetics
  • FIBMS (by examination; specialist subject Haematology) 1988
  • HC(MLT) (HKU) 1985 Medical Laboratory Technology
  • ODip (Hong Kong Polytechnic) 1980 Medical Laboratory Science
  • Brief Outline of Experience and Posts Held
    2005 - Professor, Department of Health Technology and Informatics, PolyU
    Feb 2000 - 2005 Associate Professor, Biomedical Science Section, School of Nursing, PolyU
    Oct 1992 - Jan 2000 Assistant Professor/Lecturer (College of Degree Studies), Biomedical Science Section, Department of Nursing & Health Sciences, PolyU
    Oct 1990 - Sept 1992 Lecturer, Department of Health Sciences, Hong Kong Polytechnic
    July 1987 - Nov 1990 Medical Technologist, United Christian Hospital, Hong Kong
    Jan 1987 - July 1987 Acting Medical Technologist, United Christian Hospital, Hong Kong
    Sept 1980 - Jan 1987 Medical Laboratory Technician II, United Christian Hospital, Hong Hong
    Research Interests
    Genetic variation: its detection, application and significance in relation to human health-related conditions. Genetic analysis of complex diseases, pharmacogenomics and molecular diagnostics
    Service to Professional & Scientific Bodies, Consultancies
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  • External examiners of research postgraduate degrees (1 PhD & 3 MPhil)
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  • Reviewer for journals (Blood, British Journal of Haematology, BMC Genetics, Clinical Chemistry, Journal of Biomedicine and Biotechnology, Journal of Medical Genetics, Molecular Biology and Evolution and Vox Sanguinis,)
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  • Chairman, Examination Syllabus Subcommittee, Examination Committee of Medical Laboratory Technologists Board, HK (Jun 2006 - Jun 2006)
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  • Member, Credential and Training Subcommittee, Registration Committee of Medical Laboratory Technologisits Board, HK (Jun 2006 - Jun 2006)
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  • Founding Council Member & Academic Secretary, Hong Kong Society of Molecular Diagnostic Sciences Ltd (2003 - present)
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  • Member, Scientific Subcommittee, Ninth International Conference on Myopia held on 10-14 Nov 2002 in Hong Kong/Guangzhou.
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  • Member, Organizing Committee, Joint Symposium on Frontiers of Medical Genetics Research, jointly hosted by the Hong Kong Medical Genetics Society and Department of Nursing and Health Sciences (PolyU), 8 Sept 2001, Hong Kong.
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  • Member, Scientific and Medical Advisory Committee, Retina Hong Kong (Nov 1999-present)
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  • Member, Organizing Committee, the Second Hong Kong Medical Genetics Conference, 15-17 Oct 1999, Hong Kong.
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  • Member, Scientific Subcommittee under the Organizing Committee for the 21st World Congress of Medical Technology (Sept 1992 - July 1994)
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  • Deputy Panel Head, Haematology & Serology Specialty in the Hong Kong Medical Technology Association Quality Assurance Program (1991-Sept 94); Member (Sept 95 - Sept 96 & Nov 97 - present)
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  • Member, Panel of Examiners in Haematology, Examination Committee, Medical Laboratory Technologists Board, Supplementary Medical Professions Council (1990-present).
    Awards and Patents
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  • Commonwealth Academic Staff Scholarship (Sept 1994 to Sep 1997)
    This was awarded by the Commonwealth Scholarship Commission in the United Kingdom for full-time PhD studies in Human Genetics at the University College London, University of London, UK
    Representative Publications (Journal Articles, Book Chapters, Monographs and Conference Papers; Total: 95)
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  • Yip SP, Choi PS, El-Zawahri MM, Luqmani Y. ABO blood group in Kuwaitis: detailed allele frequency distribution and identification of novel alleles. Transfusion 2005 (re-submitted
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  • Jim JJT, Noponen-Hietala N, Cheung KMC, Ott J, Karppinen J, Sahraravand A, Luk KDK, Yip SP, Sham PC, Song YQ, Leung JCY, Cheah KSE, Ala-Kokko L, Chan D. The trp2 allele of collagen IX is an age-dependent risk factor for the development and severity of intervertebral disc degeneration. Spine 2005 (in press).
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  • Yip SP, Fung LF, Lo STH. Rapid detection of Southeast Asian -thalassaemia mutations by non-isotopic multiplex PCR-SSCP. Genet Test 2004; 8: 104-108.
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  • Han W, Yip SP, Wan J, Yap MKH. Using denaturing HPLC for SNP discovery and genotyping, and establishing the linkage disequilibrium pattern for the all-trans-retinol dehydrogenase (RDH8) gene. J Hum Genet 2004;49:16-23.
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  • Yip SP, Pun SF, Leung KH, Lee SY. Rapid simultaneous genotyping of five common Southeast Asian -thalassemia mutations by multiplex minisequencing and denaturaing HPLC. Clin Chem 2003; 49: 1656-1659
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  • Yip SP, Leung KH, Lin CK. Extent and distribution of linkage disequilibrium around the SLC11A1 locus. Genes Immun 2003; 4: 212-221
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  • Yip SP, Lee SY, To SST, Wong ML. An improved real-time PCR assay for homogeneous multiplex genotyping of four CYP2C9 alleles with hybridization probes. Clin Chem 2003; 49: 2109-2111
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  • Yip SP, Chee KY, Chan PY, Chow EYD, Wong HF. Molecular genetic analysis of para-Bombay phenotypes in Chinese: a novel non-functional FUT1 allele is identified. Vox Sang 2002; 83: 258-262
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  • Yip SP. Sequence variation at the human ABO locus. Ann Hum Genet 2002; 66: 1-27.
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  • Yip SP. Single-tube multiplex PCR-SSCP analysis distinguishes seven common ABO alleles and readily identifies new alleles. Blood 2000; 95: 1487-1492
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  • Yip SP, Lovegrove JU, Rana NA Hopkinson DA, Whitehouse DB. Mapping recombination hotspots in human phosphoglucomutase (PGM1). Hum Mol Genet 1999; 8: 1699-1706
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  • Yip SP, Putt W, Hopkinson DA, Whitehouse DB. Identification and characterization of polymorphisms in human phosphoglucomutase (PGM1). Ann Hum Genet 1999; 63: 129-140
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  • Yip SP, Hopkinson DA, Whitehouse DB. Improvement of SSCP analysis by use of denaturants. BioTechniques 1999; 27: 20-24
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  • Yip SP, Choy WL, Chan CW, Choi CH. The absence of a B allele in acquired B blood group phenotype confirmed by a DNA based genotyping method. J Clin Pathol 1996; 49: 180-181