Assistant Professor
Parco Siu photo
Parco Ming-Fai SIU

  • CBiol MIBiol, 2006

  • PhD, Exercise Physiology minor in Molecular Biology, West Virginia University School of Medicine, 2005

  • MPhil, Exercise Physiology, The Chinese University of Hong Kong, 2001

  • BSc(Hons), Biology, The Hong Kong University of Science and Technology, 1999

  • Brief Outline of Experience and Posts Held
    2006 - Present

    Assistant Professor, Department of Health Technology and Informatics

    The Hong Kong Polytechnic University

    2005 - 2006

    Research Fellow, Beth Israel Deaconess Medical Center

    Harvard Medical School

    Research Interests
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  • Muscle Biology and Neuromusculoskeletal Science
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  • Exercise Science and Sports Medicine
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  • Cellular, Tissue and Genetic Engineering
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  • Oxidative Stress, Cell Death and Apoptosis
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  • Muscle Wasting Cachexia, Aging Sarcopenia, Spaceflight, Neuromuscular Disorder, Heart Disease/Failure
    Service to Professional & Scientific Bodies, Membership of Professional & Learned Societies
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  • Invited Conference Session Chair, "Muscle: Cellular and Molecular Mechanisms", American College of Sports Medicine 53rd Annual Meeting, Denver CO, 2006 Jun
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  • Invited Symposium Speaker, "The Role of Apoptosis and Aging in Skeletal Muscle", American College of Sports Medicine 53rd Annual Meeting, Denver CO, 2006 Jun
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  • Invited Seminar Speaker, "The Role of Apoptosis in Muscle Remodeling", Department of Kinesiology,

    University of Massachusetts, Amherst MA, 2006 Apr

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  • Invited Journal Reviewer: FASEB Journal, American Journal of Physiology - Regulatory, Integrative Comparative Physiology, 2005 -
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  • Laboratory Safety Officer, Beth Israel Deaconess Medical Center, Harvard Medical School, 2005 - 2006
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  • Guest Speaker, "Muscle Properties, Muscle Stem Cell and Resistance Training", Physical Fitness Association of Hong Kong China, Hong Kong, 2004 Jan

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  • Guest Speaker, "Diabetes Mellitus and Exercise", Physical Fitness Association of Hong Kong China, Hong Kong,

    2004 Jan

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  • Guest Speaker, "Antioxidant and Exercise", Physical Fitness Association of Hong Kong China, Hong Kong, 2003 Dec
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  • Member, Institute of Biology (MIBiol), 2006 -

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  • Member, American Heart Association (AHA), 2005 -
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  • Member, American Physiological Society (APS), 2003 -
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  • Member, Society for Free Radical Biology and Medicine (SFRBM), 2003 -

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  • Member, Society for Experimental Biology and Medicine (SEBM), 2003 - 2006
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  • Member, American College of Sports Medicine (ACSM), 2001 -

    Awards
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  • Gravitational Physiology Award for Beginning Investigator, American Physiological Society, 2006
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  • Young Investigator Award, Society for Experimental Biology and Medicine, 2005
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  • National Student Research Award, American College of Sports Medicine, 2005
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  • 1st Place Poster Presenter and 2nd Place Oral Presenter Awards, Annual Van Liere Research Convocation,

    West Virginia University School of Medicine, 2005

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  • Outstanding PhD Student Award, West Virginia University School of Medicine, 2004 and 2005
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  • Award of Madam Yeung Choi Lau Memorial Scholarship, The Chinese University of Hong Kong, 2001
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  • Dean List Award, The Hong Kong University of Science and Technology, 1998
    Representative Publications (Journal Articles, Book Chapters, Monographs and Conference Papers; Total: 51)

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  • Siu PM and Alway SE. Deficiency of the Bax gene attenuates denervation-induced apoptosis. Apoptosis, 11(6): 967-981, 2006.

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  • Pistilli EE, Siu PM, and Alway SE. Molecular regulation of apoptosis in fast plantaris muscles of aged rats. Journal of Gerontology: Biological Sciences, 61(3): 245-255, 2006.
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  • Siu PM and Alway SE. Aging alters the reduction of pro-apoptotic signaling in response to loading-induced hypertrophy. Experimental Gerontology, 41(2): 175-188, 2006.
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  • Siu PM, Pistilli EE, Murlasits Z, and Alway SE. Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats. Journal of Applied Physiology, 100(3): 907-916, 2006.
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  • Alway SE, Siu PM, Murlasits Z, and Butler DC. Muscle hypertrophy models: applications for research on aging (Invited review paper). Canadian Journal of Applied Physiology, 30(5): 591-624, 2005.

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  • Siu PM, Pistilli EE, Ryan MJ, and Alway SE. Aging sustains the hypertrophy-associated elevation of apoptotic suppressor X-linked inhibitor of apoptosis protein (XIAP) in skeletal muscle during unloading. Journal of Gerontology: Biological Sciences, 60(8): 976-983, 2005.

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  • Siu PM and Alway SE. Subcellular responses of p53 and Id2 in fast and slow skeletal muscles in response to stretch-induced overload. Journal of Applied Physiology, 99(5): 1897-1904, 2005.
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  • Siu PM and Alway SE. Age-related apoptotic responses to stretch-induced overload in quail slow-tonic skeletal muscle. American Journal of Physiology: Cell Physiology, 289(5): C1105-1113, 2005.
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  • Siu PM, Pistilli EE, and Alway SE. Apoptotic responses to hindlimb suspension in gastrocnemius muscles from young adult and aged rats. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 289(4): R1015-1026, 2005.

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  • Siu PM, Bryner RW, Murlasits Z, and Alway SE. Response of XIAP, ARC, and FLIP apoptotic suppressors to 8-weeks of treadmill running in rat heart and skeletal muscle. Journal of Applied Physiology, 99(1): 204-209, 2005.

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  • Siu PM and Alway SE. Activated mitochondrial apoptotic signalling in denervated rat skeletal muscle. Journal of Physiology, 565: 309-323, 2005.
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  • Siu PM and Alway SE. Id2 and p53 participate in apoptosis during unloading-induced muscle atrophy. American Journal of Physiology: Cell Physiology, 288(5): C1058-1073, 2005.
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  • Siu PM, Pistilli EE, Butler DC, and Alway SE. Aging influences the cellular and molecular responses of apoptosis to skeletal muscle unloading. American Journal of Physiology: Cell Physiology, 288(2): C338-349, 2005.

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  • Siu PM, Bryner RW, Martyn JK, and Alway SE. Apoptotic adaptations from exercise training in skeletal and cardiac muscles. FASEB Journal 18(10): 1150-1152, 2004.

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  • Siu PM, Donley DA, Bryner RW, and Alway SE. Myogenin and oxidative enzyme gene expression levels are elevated in rat soleus muscles after endurance training. Journal of Applied Physiology 97(1): 277-285, 2004.
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  • Siu PM and Wong SH. Use of glycemic index: effects on feeding patterns and exercise performance (Review paper). Journal of Physiological Anthropology and Applied Human Science 23(1): 1-6, 2004.
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  • Siu PM, Wong SH, Morris JG, Lam CW, Chung PK, and Chung S. Effect of frequency of carbohydrate feedings on recovery and subsequent run. Medicine and Science in Sports and Exercise 36(2): 315-323, 2004.
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  • Siu PM, Donley DA, Bryner RW, and Alway SE. Response of citrate synthase expression and enzymatic activity to endurance training in skeletal and cardiac muscles. Journal of Applied Physiology 94(2): 555-560, 2003.